Clinical and echocardiographic correlates of elevated troponin in amyloid light-chain cardiac amyloidosis

American Journal of Cardiology

Volumn 110, Issue 8, 2012, Pages 1180-1184

  Apridonidze, Teimuraz ^a   Steingart, Richard M ^a   Comenzo, Raymond L ^b   Hoffman, James ^c   Goldsmith, Yuliya ^d   Bella, Jonathan N ^e   Landau, Heather ^a   Liu, Jennifer E ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID A PROTEIN; BRAIN NATRIURETIC PEPTIDE; TROPONIN I;

ADULT; ARTICLE; BIOCHEMISTRY; CARDIAC PATIENT; CEREBROVASCULAR ACCIDENT; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE CLEARANCE; ECHOCARDIOGRAPHY; FEMALE; FLOW RATE; HAZARD RATIO; HEART AMYLOIDOSIS; HEART BEAT; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HUMAN; LIGHT CHAIN; MAJOR CLINICAL STUDY; MALE; MORPHOLOGY; MORTALITY; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; SURVIVAL; UNIVARIATE ANALYSIS;

AGED; AMYLOIDOSIS; BIOLOGICAL MARKERS; BIOPSY; CARDIOVASCULAR DISEASES; CHI-SQUARE DISTRIBUTION; ECHOCARDIOGRAPHY, DOPPLER; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PROPORTIONAL HAZARDS MODELS; SURVIVAL RATE; TROPONIN;

EID: 84866734222     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2012.05.061     Document Type: Article

References (26)

1. W.C. Roberts, B.F. Waller Cardiac amyloidosis causing cardiac dysfunction: analysis of 54 necropsy patients Am J Cardiol 52 1983 137 146
2. N.J. Bahlis, H.M. Lazarus Multiple myeloma-associated AL amyloidosis: is a distinctive therapeutic approach warranted? Bone Marrow Transplant 38 2006 7 15
3. R.A. Kyle, M.A. Gertz Primary systemic amyloidosis: clinical and laboratory features in 474 cases Semin Hematol 32 1995 45 59
4. R.A. Kyle, M.A. Gertz, P.R. Greipp, T.E. Witzig, J.A. Lust, M.Q. Lacy, T.M. Therneau Long-term survival (10 years or more) in 30 patients with primary amyloidosis Blood 93 1999 1062 1066
5. A. Dispenzieri, R.A. Kyle, M.A. Gertz, T.M. Therneau, W.L. Miller, K. Chandrasekaran, J.P. McConnell, M.F. Burritt, A.S. Jaffe Survival in patients with primary systemic amyloidosis and raised serum cardiac troponins Lancet 361 2003 1787 1789
6. G. Palladini, C. Campana, C. Klersy, A. Balduini, G. Vadacca, V. Perfetti, S. Perlini, L. Obici, E. Ascari, G.M. D'Eril, R. Moratti, G. Merlini Serum N-terminal pro-brain natriuretic peptide is a sensitive marker of myocardial dysfunction in AL amyloidosis Circulation 107 2003 2440 2445
7. J.B. Selvanayagam, P.N. Hawkins, B. Paul, S.G. Myerson, S. Neubauer Evaluation and management of the cardiac amyloidosis J Am Coll Cardiol 50 2007 2101 2110
8. R.L. Comenzo How I treat amyloidosis Blood 114 2009 3147 3157
9. D. Lebovic, J. Hoffman, B.M. Levine, H. Hassoun, H. Landau, Y. Goldsmith, M.S. Maurer, R.M. Steingart, A.D. Cohen, R.L. Comenzo Predictors of survival in patients with systemic light-chain amyloidosis and cardiac involvement initially ineligible for stem cell transplantation and treated with oral melphalan and dexamethasone Br J Haematol 143 2008 369 373
10. L. Cueto-Garcia, G.S. Reeder, R.A. Kyle, D.L. Wood, J.B. Seward, J. Naessens, K.P. Offord, P.R. Greipp, W.D. Edwards, A.J. Tajik Echocardiographic findings in systemic amyloidosis: spectrum of cardiac involvement and relation to survival J Am Coll Cardiol 6 1985 737 743
11. A.L. Klein, L.K. Hatle, C.P. Taliercio, J.K. Oh, R.A. Kyle, M.A. Gertz, K.R. Bailey, J.B. Seward, A.J. Tajik Prognostic significance of Doppler measures of diastolic function in cardiac amyloidosis A Doppler echocardiography study Circulation 83 1991 808 816
12. R.A. Kyle, P.R. Greipp, W.M. O'Fallon Primary systemic amyloidosis: multivariate analysis for prognostic factors in 168 cases Blood 68 1986 220 224
13. C. Tei, K.S. Dujardin, D.O. Hodge, R.A. Kyle, A.J. Tajik, J.B. Seward Doppler index combining systolic and diastolic myocardial performance: clinical value in cardiac amyloidosis J Am Coll Cardiol 28 1996 658 664
14. M.A. Gertz, R. Comenzo, R.H. Falk, J.P. Fermand, B.P. Hazenberg, P.N. Hawkins, G. Merlini, P. Moreau, P. Ronco, V. Sanchorawala, O. Sezer, A. Solomon, G. Grateau Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004 Am J Hematol 79 2005 319 328
15. R.M. Lang, M. Bierig, R.B. Devereux, F.A. Flachskampf, E. Foster, P.A. Pellikka, M.H. Picard, M.J. Roman, J. Seward, J.S. Shanewise, S.D. Solomon, K.T. Spencer, M.S. Sutton, W.J. Stewart Chamber Quantification Writing Group, American Society of Echocardiography's Guidelines and Standards Committee, European Association of Echocardiography Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology J Am Soc Echocardiogr 18 2005 1440 1463
16. W.J. Manning, D.I. Silverman, S.E. Katz, P.S. Douglas Atrial ejection force: a noninvasive assessment of atrial systolic function J Am Coll Cardiol 22 1993 221 225
17. R.V. Cantwell, R.J. Aviles, J. Bjornsson, R.S. Wright, W.K. Freeman, J.K. Oh, J.D. Hoyer, S. Markovic, A.S. Jaffe Cardiac amyloidosis presenting with elevations of cardiac troponin I and angina pectoris Clin Cardiol 25 2002 33 37
18. W.L. Miller, R.S. Wright, C.G. McGregor, A. Dispenzieri, J.P. McConnell, M.F. Burritt, A.S. Jaffe Troponin levels in patients with amyloid cardiomyopathy undergoing cardiac transplantation Am J Cardiol 88 2001 813 815
19. I.S. Syed, J.F. Glockner, D. Feng, P.A. Araoz, M.W. Martinez, W.D. Edwards, M.A. Gertz, A. Dispenzieri, J.K. Oh, D. Bellavia, A.J. Tajik, M. Grogan Role of cardiac magnetic resonance imaging in the detection of cardiac amyloidosis JACC Cardiovasc Imaging 3 2010 155 164
20. R. Capone, E.A. Amsterdam, D.T. Mason, R. Zelis Systemic amyloidosis, functional coronary insufficiency, and autonomic impairment Ann Intern Med 76 1972 599 603
21. P. Kinnunen, O. Vuolteenaho, H. Ruskoaho Mechanisms of atrial and brain natriuretic peptide release from rat ventricular myocardium: effect of stretching Endocrinology 132 1993 1961 1970
22. G. Takemura, Y. Takatsu, K. Doyama, H. Itoh, Y. Saito, M. Koshiji, F. Ando, T. Fujiwara, K. Nakao, H. Fujiwara Expression of atrial and brain natriuretic peptides and their genes in hearts of patients with cardiac amyloidosis J Am Coll Cardiol 31 1998 745 765
23. M. Nordlinger, B. Magnani, M. Skinner, R.H. Falk Is elevated plasma B-natriuretic peptide in amyloidosis simply a function of the presence of heart failure? Am J Cardiol 96 2005 982 984
24. A. Dispenzieri, M.A. Gertz, R.A. Kyle, M.Q. Lacy, M.F. Burritt, T.M. Therneau, P.R. Greipp, T.E. Witzig, J.A. Lust, S.V. Rajkumar, R. Fonseca, S.R. Zeldenrust, C.G. McGregor, A.S. Jaffe Serum cardiac troponins and N-terminal pro-brain natriuretic peptide: A staging system for primary systemic amyloidosis J Clin Oncol 22 2004 3751 3757
25. A.V. Kristen, J.B. Perz, S.O. Schonland, U. Hegenbart, P.A. Schnabel, J.H. Kristen, H. Goldschmidt, H.A. Katus, T.J. Dengler Non-invasive predictors of survival in cardiac amyloidosis Eur J Heart Fail 9 2007 617 624
26. D. Bellavia, P.A. Pellikka, G.B. Al-Zahrani, T.P. Abraham, A. Dispenzieri, C. Miyazaki, M. Lacy, C.G. Scott, J.K. Oh, F.A. Miller Independent predictors of survival in primary systemic (Al) amyloidosis, including cardiac biomarkers and left ventricular strain imaging: an observational cohort study J Am Soc Echocardiogr 23 2010 643 652