Brain-derived neurotrophic factor levels in women with postpartum affective disorder and suicidality

Neurochemical Research

Volumn 37, Issue 10, 2012, Pages 2229-2234

  Pinheiro, Ricardo Tavares ^a   Pinheiro, Karen Amaral Tavares ^a   Da Cunha Coelho, Fábio Monteiro ^a   De Ávila Quevedo, Luciana ^a   Gazal, Marta ^a   Da Silva, Ricardo Azevedo ^a   Giovenardi, Márcia ^b   Lucion, Aldo Bolten ^b   De Souza, Diogo Onofre ^c   Portela, Luis Valmor ^c   Oses, Jean Pierre ^a  

^a CATHOLIC UNIVERSITY OF PELOTAS   (Brazil)

^b UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Postpartum affective disorder; Serum brain derived neurotrophic factor (BDNF); Suicidality

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; ARTICLE; CROSS-SECTIONAL STUDY; DEPRESSION; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LIFE EVENT; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MANIA; MATERNAL DISEASE; MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW; MIXED MANIA AND DEPRESSION; MULTIVARIATE ANALYSIS; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; POSTPARTUM AFFECTIVE DISORDER; PRIORITY JOURNAL; PUERPERIUM; SUICIDAL BEHAVIOR;

ADULT; BRAIN-DERIVED NEUROTROPHIC FACTOR; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LINEAR MODELS; MIDDLE AGED; MOOD DISORDERS; POSTPARTUM PERIOD; PREGNANCY; SUICIDAL IDEATION;

EID: 84866728800     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-012-0851-9     Document Type: Article

References (26)

1. Kelly E, Sharma V (2010) Diagnosis and treatment of postpartum bipolar depression. Expert Rev Neurother 10:1045-1051
2. aan het Rot M, Mathew SJ, Charney DS (2009) Neurobiological mechanisms in major depressive disorder. CMAJ 3:180-183
3. Pinheiro RT, da Silva RA, Magalhães PV, Horta BL, Pinheiro KA (2008) Two studies on suicidality in the postpartum. Acta Psychiatr Scand 118:160-163
4. Lindahl V, Pearson JL, Colpe L (2005) Prevalence of suicidality during pregnancy and the postpartum. Arch Womens Ment Health 8:77-87
5. Dwivedi Y (2009) Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatr Dis Treat 5:433-434
6. Krishnan V, Nestler EJ (2008) The molecular neurobiology of depression. Nature 455:894-902
7. Stein DJ, Daniels WMU, Savitz J, Harvey BH (2008) Brainderived neurotrophic factor: hypothesis of psychopathology. CNS Spectr 13:945-949
8. Tsai SJ (2005) Possible involvement of the BDNF-dependent pathway in treatment emergent suicidality or decreased response to antidepressants. Med Hypotheses 65:942-946
9. Dwivedi Y (2010) Brain-derived neurotrophic factor and suicide pathogenesis. Ann Med 42:87-96
10. Kim YK, Lee HP, Won SD, Park EY, Lee HY, Lee BH, Lee SW, Yoon D, Han C, Kim DJ, Choi SH (2007) Low plasma BDNF is associated with suicidal behavior in major depression. Prog Neuropsychopharmacol Biol Psychiatry 31:78-85
11. Pandey GN, Ren X, Rizavi HS, Conley RR, Roberts RC, Dwivedi Y (2008) Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims. Int J Neuropsychopharmacol 11:1047-1061
12. Grillo RW, Ottoni GL, Leke R, Souza DO, Portela LV, Lara DR (2007) Reduced serum BDNF levels in schizophrenic patients on clozapine or typical antipsychotics. J Psychiatr Res 41:31-35
13. Machado-Vieira R, Dietrich MO, Leke R, Cereser VH, Zanatto V, Kapczinski F, Souza DO, Portela LV, Gentil V (2007) Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode. Biol Psychiatry 61:142-144
14. Amorim P (2000) Mini Internacional Neuropsychiatric Interview (MINI): validação de entrevista breve para diagnóstico de transtornos mentais. Rev Bras Psiquiatr 22:106-115
15. Savoia MG (1999) Escalas de eventos vitais e de estratégias de enfrentamento (coping)/life events and coping scales. Rev Psiquiatr Clin 26:57-67
16. Chen B, Dowlatshahi D, Macqueen GM, Wang JF, Young LT (2001) Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 50:260-265
17. Lee BH, Kim YK (2011) Potential peripheral biological predictors of suicidal behavior in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 35:842-847
18. Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN (2003) Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 60:804-815
19. Karege F, Vaudan G, Schwald M, Perroud N, La Harpe R (2005) Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res 136:29-37
20. Erickson KI, Prakash RS, Voss MW, Chaddock L, Heo S, McLaren M, Pence BD, Martin SA, Vieira VJ, Woods JA, McAuley E, Kramer AF (2010) Brain-derived neurotrophic factor is associated with age-related decline in hippocampal volume. J Neurosci 30:5368-5375
21. Elzinga BM, Molendijk ML, Oude Voshaar RC, Bus BA, Prickaerts J, Spinhoven P, Penninx BJ (2011) The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met. Psychopharmacology (Berl) 214(1):319-328
22. Lommatzsch M, Hornych K, Zingler C, Schuff-Werner P, Höppner J, Virchow JC (2006) Maternal serum concentrations of BDNF and depression in the perinatal period. Psychoneuroendocrinology 31:388-394
23. Lopez JF, Palkovits M, Arato M, Mansour A, Akil H, Watson SJ (1992) Localization and quantification of proopiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims. Neuroendocrinology 56:491-501
24. Nemeroff CB, Owens MJ, Bissette G, Andorn AC, Stanley M (1988) Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims. Arch Gen Psychiatry 45:577-579
25. Szigethy E, Conwell Y, Forbes NT, Cox C, Caine ED (1994) Adrenal weight and morphology in victims of completed suicide. Biol Psychiatry 36:374-380
26. Westrin A (2000) Stress system alterations and mood disorders in suicidal patients. A review. Biomed Pharmacother 54:142-145