Validation of the extended Tanaka column characterization protocol by multivariate analysis of chromatographic retention of low-molecular-weight analytes on reversed phase columns using methanol and acetonitrile as organic modifiers

Journal of Separation Science

Volumn 35, Issue 19, 2012, Pages 2592-2598

  Euerby, Melvin R ^a   James, Matthew ^a   Axelsson, Bengt Olof ^b   Rosén, Olof ^c   Petersson, Patrik ^b  

^a Hichrom Ltd   (United Kingdom)

^b NOVO NORDISK A S   (Denmark)

^c Umetrics AB   (Sweden)

Author keywords

Mobile phase selectivity; Principal component analysis (PCA); RP LC stationary phase characterization

Indexed keywords

ANALYTES; CHEMOMETRICES; CHROMATOGRAPHIC RETENTION; COLUMN CHARACTERIZATION; CONTRIBUTION PLOTS; LOW-MOLECULAR-WEIGHT ANALYTES; MOBILE PHASE MODIFIERS; MULTI VARIATE ANALYSIS; ORGANIC MODIFIER; RETENTION BEHAVIOR; RETENTION TIME; REVERSED-PHASE COLUMNS; SPECIFIC SELECTIVITY; STATIONARY PHASE; STATIONARY PHASIS;

ACETONITRILE; CHROMATOGRAPHY; METHANOL; PRINCIPAL COMPONENT ANALYSIS;

LOADING;

ACETONITRILE; METHANOL;

ANALYTIC METHOD; ARTICLE; CHEMOMETRIC ANALYSIS; HYDROPHOBICITY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; TANAKA COLUMN CHARACTERIZATION; VALIDATION STUDY; VALIDITY;

EID: 84866719302     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201200261     Document Type: Article

References (26)

1. Incognito, Column 2009, 5, 9-12.
2. Incognito, Column 2010, 6, 11-15.
3. Snyder, L. R., Dolan, J. W., High Performance Gradient Elution, Wiley, Hoboken, NJ 2007, pp. 108-120.
4. Channer, B., Retz, C., Euerby, M. R., Moffat, F., Chimica 2009, 63, 350-350.
5. Kromidas, S., (Ed.), HPLC Made to Measure: A Practical Handbook for Optimization, Wiley-VCH, Weinheim, Germany 2006, pp. 149-253.
6. Krisko, R. M., McLaughlin, K., Koenigbauer, M. J., Lunte, C. E., J. Chromatogr. A 2006, 1122, 186-193.
7. Wilson, N. S., Nelson, M. D., Dolan, J. W., Snyder, L. R., Wolcott, R. G., Carr, P. W., J. Chromatogr. A 2002, 961, 171-193.
8. Sander, L. C., Wise, S. A., J. Sep. Sci. 2003, 26, 283-294.
9. Neue, U. D., Serowik, E., Iraneta, P., Alden, B. A., Walter, T. H., J. Chromatogr. A 1999, 849, 87-100.
10. Kimata, K., Iwaguchi, K., Onishi, S., Jinno, K., Eksteen, R., Hosoya, K., Arki, M., Tanaka, N., J. Chromatogr. Sci. 1989, 27, 721-728.
11. Cruz, E., Euerby, M. R., Johnson, C. M., Hackett, C. A., Chromatographia 1997, 44, 151-161.
12. Euerby, M. R., Petersson, P., J. Chromatogr. A 2003, 994, 13-36.
13. Euerby, M. R., Petersson, P., J. Chromatogr. A 2005, 1088, 1-15.
14. Euerby, M. R., Petersson, P., Campbell, W., Roe, W., J. Chromatogr. A 2007, 1154, 138-151.
15. Markopoulou, C., Tweedlie, T., Watson, D., Skellern, G. G., Reda, H., Petersson, P., Bradstock, H., Euerby, M. R., Chromatographia 2009, 70, 705-715.
16. Wold, S., Geladi, P., Esbensen, K., Öhman, J., J. Chemometrics 1987, 1, 41-56.
17. Eriksson, L., Johansson, E., Kettaneh-Wold, N., Wold, S., Multi- and Megavariate Data Analysis: Principles and Applications, Umetrics AB, Umeå, Sweden 2001.
18. Fornal, E., Borman, P., Luscombe, C., Anal. Chim. Acta 2006, 570, 267-276.
19. Lombardo, F., Shalaeva, M. Y., Tupper, K. A., Gao, F., Abraham, M. H., J. Med. Chem. 2000, 43, 2922-2928.
20. Pagliara, A., Khamis, E., Trinh, A., Carrupt, P. A., Tsai, R. S., Testa, B., J. Liq. Chromatogr. 1995, 18, 1721-1745.
21. Minick, D. J., Frenz, J. H., Patrik, M. A., Brent, D. A., J. Med. Chem. 1988, 31, 1923-1933.
22. Snyder, L. R., Kirkland, J. J., Glajch, J. L., Practical HPLC Method Development, Wiley, New York 1997, pp. 239-240.
23. Neue, U. D., O'Gara, J. E., Méndez, A., J. Chromatogr. A 2006, 1127, 161-174.
24. Euerby, M. R., Schad, G., Rieger, H.-J., Molnár, I., Chromatogr. Today 2010, Dec., 13-20.
25. Horak, J., Lindner, W., J. Chromatogr. A 2008, 1191, 141-156.
26. Brambilla, R., Pires, G. P., dos Santos, J. H. Z., Miranda, M. S. L., Chornik, B., J. Electron Spectrosc. Relat. Phenom. 2007, 413, 156-158.