Serum metabonomics study of systemic lupus erythematosus by rapid resolution liquid chromatography coupled with Q-TOF mass spectrometry

Proceedings - 2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012

Volumn , Issue , 2012, Pages 507-510

  Ding, Xinghong ^a   Yu, Ying ^b  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b Zhejiang Chinese Medical Hospital   (China)

Author keywords

Biomarker; Metabonomics; Systemic lupus erythematosus

Indexed keywords

ABNORMAL METABOLISM; DISEASE BIOMARKER; HEALTHY CONTROLS; METABOLIC DATA; METABOLIC PROFILES; METABONOMICS; MONITORING AND DIAGNOSIS; ORTHOGONAL SIGNAL CORRECTION; QUADRUPOLE-TIME OF FLIGHTS; RAPID RESOLUTION; SUPERVISED PATTERN RECOGNITION; SYSTEMIC LUPUS ERYTHEMATOSUS;

AMINO ACIDS; BIOMEDICAL ENGINEERING; BIOTECHNOLOGY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PATTERN RECOGNITION; PHOSPHOLIPIDS; PORPHYRINS;

BIOMARKERS;

EID: 84866715895     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/iCBEB.2012.351     Document Type: Conference Paper

References (9)

1. G. Valesini, C. Alessandri, D. Celestino et al (2006) Anti-endothelial antibodies and neuropsychiatric systemic lupus erythematosus.Ann NY Acad Sci 1069:pp118-128
2. M. Nikpour, MB. Urowitz, D. Ibañez, et al. (2009)Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus. Arthritis Rheum , 61 : pp1152-8 .
3. J. K. Nicholson, J. Connelly, J. C. Lindon. (2002).Metabonomics: A platform for studying drug toxicity and gene function. Nature Reviews Drug Discovery, 1(2), pp153-162.
4. J. K. Nicholson, E. Holmes, J. C. Lindon,and I. D. Wilson (2004).The challenges of modeling mammalian biocomplexity. Nature Biotechnology, 22(10), pp1268-1274.
5. M. Coen, E. Holmes, J.C. Lindon and J.K. Nicholson (2008) NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chemical Research Toxicology ,21(1): pp9-27.
6. M.Z. Ding, J.S. Cheng, W.H. Xiao, B. Qiaoand Y.J. Yuan (2009)Comparative metabolomic analysis on industrial continuous and batch ethanol fermentation processes by GC-TOF-MS. Metabolomics5(2): pp229-238.
7. F.X. Zhang, Z.H. Jia, P. Gao, et al.(2009a) Metabonomics study of atherosclerosis rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. Talanta,79(3): pp836-844.
8. L.W Jia., J. Chen, P.Y. Yin, X. Lu and G.W. Xu (2008)Serum metabonomics study of chronic renal failure by ultra performance liquid chromatography coupled with Q-TOF mass spectrometry. Metabolomics, 4(2):pp83-189.
9. G.J. Obermoser, V. Pascual (2010)The interferon-alpha signature of systemic lupus erythematosus. Lupus,19:pp1012-9.