A 10-Year Analysis of the Effects of Media Coverage of Regulatory Warnings on Antidepressant Use in The Netherlands and UK

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Hernandez, Juan Francisco ^a   Mantel Teeuwisse, Aukje K ^a   van Thiel, Ghislaine J M W ^b   Belitser, Svetlana V ^a   Warmerdam, Jan ^c   de Valk, Vincent ^d   Raaijmakers, Jan A M ^a,e   Pieters, Toine ^a,f  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c IQVIA   (United States)

^d Healthcare Insurance Board (CVZ)   (Netherlands)

^e GLAXOSMITHKLINE   (Netherlands)

^f VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ESCITALOPRAM; PAROXETINE; SEROTONIN UPTAKE INHIBITOR;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG CONTROL; DRUG INFORMATION; DRUG USE; FEMALE; GEOGRAPHIC DISTRIBUTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MASS MEDIUM; NETHERLANDS; PRESCRIPTION; TIME SERIES ANALYSIS; TREND STUDY; UNITED KINGDOM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIDEPRESSIVE AGENTS; CHILD; CHILD, PRESCHOOL; COMMUNICATIONS MEDIA; DRUG PRESCRIPTIONS; GREAT BRITAIN; HISTORY, 21ST CENTURY; HUMANS; INFANT; INFANT, NEWBORN; MIDDLE AGED; NETHERLANDS; SEROTONIN UPTAKE INHIBITORS; YOUNG ADULT;

EID: 84866687500     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045515     Document Type: Article

References (58)

1. Williams D, Kelly A, Feely J, (2000) Influence of media and regulatory changes on prescribing of Cotrimoxazole and Trimethoprim in Ireland. Pharmacoepidemiol Drug Saf 9(4): 313-317.
2. David F, Archer M, (2007) Medical decisions regarding hormone therapy for menopausal women are significantly influenced by the media. Pharmacoepidemiol Drug Saf 16(1): 28-31.
3. Mebane FE (2005) The importance of news media in pharmaceutical risk communication: proceedings of a workshop. Pharmacoepidemiol Drug Saf 14(5): 297-306.
4. Brouneus F, Dahlin A, Beermann B, (2005) Press coverage and sales of Xenical in Sweden, 1998-2000. Eur J Clin Pharmacol 61(4): 285-289.
5. Martin RM, May M, Gunnell D (2006) Did intense adverse media publicity impact on prescribing of paroxetine and the notification of suspected adverse drug reactions? Analysis of routine databases, 2001-2004. Br J Clin Pharmacol 61(2): 224-228.
6. Wheeler BW, Gunnell D, Metcalfe C, Stephens P, Martin RM, (2008) The population impact on incidence of suicide and non-fatal self harm of regulatory action against the use of selective serotonin reuptake inhibitors in under 18s in the United Kingdom: ecological study. BMJ 8 336(7643): 542-545.
7. Gibbons RD, Brown CH, Hur K, Marcus SM, Bhaumik DK, et al. (2007) Early evidence on the effects of regulators' suicidality warnings on SSRI prescriptions and suicide in children and adolescents. Am J Psychiatry 164(9): 1356-1363.
8. Volkers AC, Heerdink ER, van Dijk L, (2007) Antidepressant use and off-label prescribing in children and adolescents in Dutch general practice (2001-2005). Pharmacoepidemiol Drug Saf 16(9): 1054-1062.
9. Libby AM, Brent DA, Morrato EH, Orton HD, Allen R,et al. (2007) Decline in treatment of pediatric depression after FDA advisory on risk of suicidality with SSRIs. Am J Psychiatry 164(6): 884-891.
10. Olfson M, Marcus SC, Druss BG, (2008) Effects of Food and Drug Administration warnings on antidepressant use in a national sample. Arch Gen Psychiatry 65(1): 94-101.
11. FDA. Food and Drug Administration Modernization Act of 1997. Rockville, MD: Department of Health and Human Services; 1997. Available: http://www.fda.gov/RegulatoryInformation/Legislation/FederalFoodDrugandCosmeticActFDCAct/SignificantAmendmentstotheFDCAct/FDAMA/FullTextofFDAMAlaw/default.htm. Accessed 2012 January 11.
12. BBC. Panorama: The Secrets of Seroxat. London: BBC; 2002. Available: http://news.bbc.co.uk/panorama/hi/front_page/newsid_8425000/8425414.stm. Accessed 2012 February 1.
13. Check E, (2004) Antidepressants: bitter pills. Nature 9 431(7005): 122-124.
14. FDA. Suicidality in Children and Adolescents Being Treated With Antidepressant Medications. Rockville, MD: Department of Health and Human Services; 2004. Available: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/PublicHealthAdvisories/ucm161679.htm. Accessed 2011 January 20.
15. MHRA. Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitor Antidepressants. London: Committee on Safety of Medicines; 2004. Available: http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf. Accessed 2012 August 24.
16. EMA. European Medicines Agency finalises review of antidepressants in children and adolescents. London: EMA; 2005. Available: http://www.ema.europa.eu/ema/index.jsp?curl=pages/news_and_events/news/2009/12/news_detail_000882.jsp&murl=menus/news_and_events/news_and_events.jsp&mid=WC0b01ac058004d5c1. Accessed 2011 February 4.
17. Wadman M (2004) Spitzer sues drug giant for deceiving doctors. Nature 10;429(6992): 589.
18. Check E, (2004) Analysis highlights suicide risk of antidepressants. Nature 26 430(7003): 954.
19. FDA. Antidepressant Use in Children, Adolescents, and Adults. Rockville, MD: Department of Health and Human Services; 2007. Available: http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/ucm096273.htm. Accessed 2011 February 7.
20. EMA. CHMP Assessment Report on Antidepressants. London: European Medicines Agency; 2008. Available: http://www.ema.europa.eu/docs/en_GB/document_library/Report/2010/01/WC500054061.pdf. Accessed 2011 December 18.
21. Hernandez JF, Mantel-Teeuwisse AK, van Thiel GJMW, Belitser SV, Raaijmakers JAM, et al. (2011) Publication trends in newspapers and scientific journals for SSRIs and suicidality: a systematic longitudinal study. BMJ Open 1, 2011;1(2).
22. GIPdatabank. GIPdatabank. Utrecht: CVZ; 2011. Available: http://www.gipdatabank.nl/. Accessed 2012 January 13.
23. WHO. ATC/DDD Index 2011. Geneva: WHO. Available: http://www.whocc.no/atc_ddd_index/. Accessed 2011 October 4.
24. CBS. Bevolkinsteller (Centrale Bureau van Statistiek). 2011. Available: http://www.cbs.nl/en-GB/menu/home/default.htm?Languageswitch=on. Accessed 2011 October 23.
25. Commission E. Eurostat. 2011. Available: http://epp.eurostat.ec.europa.eu/portal/page/portal/statistics/themes. Accessed 2011 October 5.
26. Xianping G (2002) Segmental Semi-Markov Models and Applications to Sequence Analysis: University of California.
27. Stolk P, Belitser SV, Leufkens HGM, Heerdink ER, (2008) Variable Access to Clopidogrel in a Harmonized EU Market. Value in Health 11(5): 989-995.
28. R-Project. The R Project for Statistical Computing. Viena, Austria: R Foundation for Statiastical Computing; 2011. Available: http://www.r-project.org/. Accessed 2012 February 13.
29. WHO. Guidelines for ATC classification and DDD assignment 2010. Available: http://www.whocc.no/filearchive/publications/2010guidelines.pdf. Accessed 2011 February 24.
30. Liem T, Heerdink E, Egberts A, Rademaker C, (2010) Quantifying antibiotic use in paediatrics: a proposal for neonatal DDDs. Eur J Clin Microbiol 29(10): 1301-1303.
31. Hall WD, Mant A, Mitchell PB, Rendle VA, Hickie IB, et al. (2003) Association between antidepressant prescribing and suicide in Australia, 1991-2000: trend analysis. BMJ 10 326(7397): 1008.
32. Milane MS, Suchard MA, Wong M-L, Licinio J, (2006) Modeling of the Temporal Patterns of Fluoxetine Prescriptions and Suicide Rates in the United States. PLoS Med 3(6): e190.
33. Grunebaum MF, Ellis SP, Li S, Oquendo MA, Mann JJ, (2004) Antidepressants and suicide risk in the United States, 1985-1999. J Clin Psychiatry 65(11): 1456-1462.
34. Korkeila J, Salminen J, Hiekkanen H, Salokangas R, (2007) Use of antidepressants and suicide rate in Finland: an ecological study. J Clin Psychiatry 68(4): 505-511.
35. Bramness JG, Walby FA, Tverdal A, (2007) The sales of antidepressants and suicide rates in Norway and its counties 1980-2004. J Affect Disorders 102(1-3): 1-9.
36. Reseland S, Bray I, Gunnell D, (2006) Relationship between antidepressant sales and secular trends in suicide rates in the Nordic countries. Brit J Psychiat 188(4): 354-358.
37. Baldessarini RJ, Tondo L, Strombom IM, Dominguez S, Fawcett J, et al. (2007) Ecological studies of antidepressant treatment and suicidal risks. Harvard Rev Psychiat 15(4): 133-145.
38. Wijlaars LPMM, Nazareth I, Petersen I, (2012) Trends in Depression and Antidepressant Prescribing in Children and Adolescents: A Cohort Study in The Health Improvement Network (THIN). PLoS ONE 7(3): e33181.
39. Reid S, Barbui C (2010) Long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants. BMJ 2010-03-26 00:00:00;340.
40. Meijer WE, Heerdink ER, Leufkens HM, Herings RC, Egberts AG, et al. (2004) Incidence and determinants of long-term use of antidepressants. E J Clin Pharmacol 60(1): 57-61.
41. CVZ. GIPeilingen. College voor zorgverzekeringen (CVZ); 2012; Available: http://www.cvz.nl/publicaties/gipeilingen. Accessed 2012 May 21.
42. Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. (2008) Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration. PLoS Med 5(2): e45.
43. Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R, (2008) Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 17 358(3): 252-260.
44. Boseley S. Prozac, used by 40m people, does not work say scientists. London, UK: Guardian Media Group; 2008. Available: http://www.guardian.co.uk/society/2008/feb/26/mentalhealth.medicalresearch. Accessed 2012 August 24.
45. McRae F. Anti-depressants taken by thousands of Brits 'do NOT work', major new study reveals. London 2008. Available: http://www.dailymail.co.uk/health/article-518669/Anti-depressants-taken-thousands-Brits-NOT-work-major-new-study-reveals.html. Accessed 2012 August 24.
46. NICE. Depression: the treatment and management of depression in adults (National Clinical Practice Guideline 90). UK: National Institute for Health and Clinical Excellence (NICE); 2009. Available: http://www.nice.org.uk/nicemedia/live/12329/45896/45896.pdf. Accessed 2011 December 19.
47. Geddes JR, Carney SM, Davies C, Furukawa TA, Kupfer DJ, et al. (2003) Relapse prevention with antidepressant drug treatment in depressive disorders: a systematic review. The Lancet 361(9358): 653-661.
48. Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JPT, et al. (2009) Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. The Lancet 373(9665): 746-758.
49. Guardian T. 'Four people dead is four too many'. London: Guardian; 2001. Available: http://www.guardian.co.uk/education/2001/aug/09/medicalscience.healthandwellbeing. Accessed 2011 December 19.
50. BBC. Antidepressant addiction warning. London: BBC; 2001. Available: http://news.bbc.co.uk/2/hi/health/1382551.stm. Accessed 2011 December 19.
51. Tonks A, (2002) Withdrawal from paroxetine can be severe, warns FDA. BMJ 324(7332): 260.
52. NHG. M44 NHG-Standaard Depressieve Stoornis (Depressie). Utrecht: Nederlands Huisartsen Genootschap; 2009. Available: http://nhg.artsennet.nl/kenniscentrum/k_richtlijnen/k_nhgstandaarden.htm- clusterN. Accessed 2012 February 13.
53. CBO. Richtlijnherziening van de Multidisciplinaire richtlijn Depressie bij volwassenen. Utrecht: Centraal BegeleidingsOrgaan; 2010. Available: http://www.cbo.nl/thema/Richtlijnen/Overzicht-richtlijnen/Geestelijke-gezondheidszorg/?p=402. Accessed 2011 December 15.
54. Gardarsdottir H, Heerdink ER, Egberts AC, (2006) Potential bias in pharmacoepidemiological studies due to the length of the drug free period: a study on antidepressant drug use in adults in the Netherlands. Pharmacoepidemiol Drug Saf 15(5): 338-343.
55. Healy D, Herxheimer A, Menkes DB, (2006) Antidepressants and Violence: Problems at the Interface of Medicine and Law. PLoS Med 3(9): e372.
56. Nemeroff CB, Kalali A, Keller MB, Charney DS, Lenderts SE, et al. (2007) Impact of Publicity Concerning Pediatric Suicidality Data on Physician Practice Patterns in the United States. Arch Gen Psychiatry 64(4): 466-472.
57. Libby AM, Orton HD, Valuck RJ, (2009) Persisting decline in depression treatment after FDA warnings. Arch Gen Psychiatry 66(6): 633-639.
58. Isacsson G, Holmgren A, Ösby U, Ahlner J, (2009) Decrease in suicide among the individuals treated with antidepressants: A controlled study of antidepressants in suicide, Sweden 1995-2005. Acta Psychiat Scand 120(1): 37-44.