Screening for cervical neoplasia: A community-based trial comparing Pap staining, human papilloma virus testing, and the new bi-functional celldetect® stain

Diagnostic Cytopathology

Volumn 40, Issue 12, 2012, Pages 1054-1061

  Idelevich, Pavel ^a   Kristt, Don ^b,c   Schechter, Eduardo ^d   Lew, Sylvia ^e   Elkeles, Adi ^a   Terkieltaub, Dov ^a   Rivkin, Ilia ^a   Bruchim, Ilan ^e,f   Fishman, Ami ^e,f  

^a Zetiq Technologies Ltd   (Israel)

^b RABIN MEDICAL CENTER   (Israel)

^c BAR ILAN UNIVERSITY   (Israel)

^d MACCABI HEALTHCARE SERVICES   (Israel)

^e MEIR MEDICAL CENTER   (Israel)

^f TEL AVIV UNIVERSITY   (Israel)

Author keywords

CellDetect stain; cervical neoplasia; cervical screening

Indexed keywords

ARTICLE; BIOPSY TECHNIQUE; CANCER DIAGNOSIS; CANCER SCREENING; CELLDETECT STAINING; CLINICAL EVALUATION; DIAGNOSTIC TEST ACCURACY STUDY; FOLLOW UP; HUMAN; INTERMETHOD COMPARISON; MORPHOLOGY; PAPANICOLAOU TEST; PREDICTOR VARIABLE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; STAINING; UTERINE CERVIX CANCER; VIRUS DETECTION; WART VIRUS;

BIOPSY; CERVICAL INTRAEPITHELIAL NEOPLASIA; COMMUNITY HEALTH CENTERS; DNA, VIRAL; EARLY DETECTION OF CANCER; FEMALE; HUMANS; OBSERVER VARIATION; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; REAGENT KITS, DIAGNOSTIC; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STAINING AND LABELING; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 84866682136     PISSN: 87551039     EISSN: 10970339     Source Type: Journal    
DOI: 10.1002/dc.21729     Document Type: Article

References (15)

1. Papanicolaou GN, Traut NF,. The diagnostic value of vaginal smears in carcinoma of the uterus. Am J Obstet Gynecol 1941; 42: 193-206.
2. Papanicolaou GN,. Atlas of Exfoliative Cytology. Cambridge, MA: Harvard University Press; 1954.
3. Dewar MA, Hall K, Percalski J,. Cervical cancer screening. Past success and future challenge. Prim Care 1992; 19: 589-606.
4. Khodakarami N, Farzaneh F, Aslani F, Alizadeh K,. Comparison of Pap smear, visual inspection with acetic acid, and digital cervicography as cervical screening strategies. Arch Gynecol Obstet, in press.
5. Huh WK,. The changing face of cervical cancer screening in the United States. J Natl Compr Canc Netw 2010; 8: 1329-1330.
6. Aggarwal P, Batra S, Gandhi G, Zutshi V,. Comparison of Papanicolaou test with visual detection tests in screening for cervical cancer and developing the optimal strategy for low resource settings. Int J Gynecol Cancer 2010; 20: 862-868.
7. Sasagawa T,. Updated cervical cancer screening; human papilloma virus and Papanicolaou tests. Rinsho Byori 2009; 57: 905-912.
8. Halfon P, Benmoura D, Agostini A, et al. Stepwise algorithm combining HPV high-risk DNA-based assays and RNA-based assay for high grade CIN in women with abnormal smears reffered to colposcopy. Cancer Biomark 2010; 7: 133-139.
9. Idelevich P, Kristt D, Okon E, et al. Novel histochemical stain for tinctorial detection of cancer and neoplastic cells. J Histotechnol 2009; 32: 97-105.
10. Sagiv I, Idelevich P, Rivkin I, Margalit R, Elkeles A, Levitzki A,. A color discriminating broad range cell staining technology for early detection of cell transformation. J Carcinog 2009; 8: 16.
11. Idelevich P, Elkeles A, Okon E, et al. Novel dual-function CellDetect® staining technology: Wedding morphology and tinctorial discrimination to detect cervical neoplasia. Diagn Pathol 2010; 5: 70.
12. Fleiss JL, Tytun A, Ury HK,. A simple approximation for calculating sample sizes for comparing independent proportions. Biometrics 1980; 36: 343-346.
13. Fleiss JL,. Confidence Interval for π1-π2 (Continuity corrected)-Statistical Methods for Rates and Proportions. 2nd ed. New York: Wiley, 1973.
14. Kraemer HC,. Agreement between two dichotomous ratings (intraclass kappa). 2x2 Kappa coefficients: Measures of agreement or association. Biometrics 1989; 45: 269-287.
15. Landis JR, Koch GG,. An application of hierarchical kappa-type statistics in the assessment of majority agreement among multiple observers. Biometrics 1977; 33: 363-374.