Identification of Leishmania tropica from micro-foci of cutaneous leishmaniasis in the Kenyan Rift valley

Pathogens and Global Health

Volumn 106, Issue 3, 2012, Pages 159-165

  Odiwuor, Samwel ^a,b,c   Muia, Alfred ^a   Magiri, Charles ^a   Maes, Ilse ^b   Kirigi, George ^a   Dujardin, Jean Claude ^b,c   Wasunna, Monique ^a   Mbuchi, Margaret ^a   Van der Auwera, Gert ^b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Diagnosis; Kenya; Leishmania tropica; Molecular typing; PCR

Indexed keywords

RIBOSOME DNA;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENDEMIC DISEASE; FEMALE; HUMAN; INCIDENCE; KENYA; LEISHMANIA TROPICA; MALE; MICROSCOPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE CONTROL; PARASITE IDENTIFICATION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SCHOOL CHILD; SKIN LEISHMANIASIS; SPECIES IDENTIFICATION;

ADOLESCENT; ADULT; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; KENYA; LEISHMANIA TROPICA; LEISHMANIASIS, CUTANEOUS; MALE; MICROSCOPY; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RNA, PROTOZOAN; RNA, RIBOSOMAL; RURAL POPULATION; SKIN;

EID: 84866671178     PISSN: 20477724     EISSN: 20477732     Source Type: Journal    
DOI: 10.1179/2047773212Y.0000000015     Document Type: Article

References (23)

1. Perkins PV, Githure JI, Mebrahtu Y, Kiilu G, Anjili C, Ngumbi PS, et al. Isolation of Leishmania donovani from Phlebotomus martini in Baringo district, Kenya. Trans R Soc Trop Med Hyg. 1988;82:695-700.
2. Mebrahtu Y, Oster CN, Shatry AM, Hendricks LD, Githure JI, Rees PH, et al. Cutaneous leishmaniasis caused by Leishmania tropica in Kenya. Trans R Soc Trop Med Hyg. 1987;81:923-924.
3. Mebrahtu Y, Lawyer P, Githure J, Kager P, Leeuwenburg J, Perkins P, et al. Indigenous human cutaneous leishmaniasis caused by Leishmania tropica in Kenya. Am J Trop Med Hyg. 1988;39:267-273.
4. Sang DK, Okelo GB, Chance ML. Cutaneous leishmaniasis due to Leishmania aethiopica, on Mount Elgon, Kenya. Ann Trop Med Parasitol. 1993;87:349-357.
5. Mebrahtu YB, Lawyer PG, Pamba H, Koech D, Perkins PV, Roberts CR, et al. Biochemical characterization and zymodeme classification of Leishmania isolates from patients, vectors, and reservoir hosts in Kenya. Am J Trop Med Hyg. 1992;47:852-892.
6. Tonui WK. Situational analysis of leishmaniases research in Kenya. Afr J Health Sci. 2006;13:7-21.
7. Mebrahtu YB, Lawyer PG, Ngumbi PM, Kirigi G, Mbugua J, Gachihi G, et al. A new rural focus of cutaneous leishmaniasis caused by Leishmania tropica in Kenya. Trans R Soc Trop Med Hyg. 1992;86:381-387.
8. Sang DK, Okelo GB, Ndegwa CW, Ashford RW. New foci of cutaneous leishmaniasis in central Kenya and the Rift Valley. Trans R Soc Trop Med Hyg. 1993;87:629-632.
9. Massamba NN, Mutinga MJ, Kamau CC. Characterisation of Leishmania isolates from Laikipia District, Kenya. Acta Trop. 1998;71:293-303.
10. Sang DK, Njeru WK, Ashford RW. A zoonotic focus of cutaneous leishmaniasis due to Leishmania tropica at Utut, Rift Valley Province, Kenya. Trans R Soc Trop Med Hyg. 1994;88:35-37.
11. Lawyer PG, Mebrahtu YB, Ngumbi PM, Mwanyumba P, Mbugua J, Kiilu G, et al. Phlebotomus guggisbergi (Diptera: Psychodidae), a vector of Leishmania tropica in Kenya. Am J Trop Med Hyg. 1991;44:290-298.
12. Johnson RN, Ngumbi PM, Mwanyumba JP, Roberts CR. Host feeding preference of Phlebotomus guggisbergi, a vector of Leishmania tropica in Kenya. Med Vet Entomol. 1993;7:216-218.
13. Basiye FL, Schoone GJ, Beld M, Minnaar R, Ngeranwa JN, Wasunna MK, et al. Comparison of short-term and long-term protocols for stabilization and preservation of RNA and DNA of Leishmania, Trypanosoma, and Plasmodium. Diagn Microbiol Infect Dis. 2011;69:66-73.
14. Chulay JD, Anzeze EM, Koech DK, Bryceson AD. High-dose sodium stibogluconate treatment of cutaneous leishmaniasis in Kenya. Trans R Soc Trop Med Hyg. 1983;77:717-721.
15. Boom R, Sol CJ, Salimans MM, Jansen CL, Wertheim-van Dillen PM, van der Noordaa J. Rapid and simple method for purification of nucleic acids. J Clin Microbiol. 1990;28:495-503.
16. Deborggraeve S, Boelaert M, Rijal S, De Doncker S, Dujardin JC, Herdewijn P, et al. Diagnostic accuracy of a new Leishmania PCR for clinical visceral leishmaniasis in Nepal and its role in diagnosis of disease. Trop Med Int Health. 2008;13:1378-1383.
17. Ogado Ceasar Odiwuor S, Ageed Saad A, De Doncker S, Maes I, Laurent T, El Safi S, et al. Universal PCR assays for the differential detection of all Old World Leishmania species. Eur J Clin Microbiol Infect Dis. 2011;30:209-218.
18. Mebrahtu YB, Van Eys G, Guizani I, Lawyer PG, Pamba H, Koech D, et al. Human cutaneous leishmaniasis caused by Leishmania donovani s. l. in Kenya. Trans R Soc Trop Med Hyg. 1993;87:598-601.
19. Elamin EM, Guerbouj S, Musa AM, Guizani I, Khalil EA, Mukhtar MM, et al. Uncommon clinical presentations of cutaneous leishmaniasis in Sudan. Trans R Soc Trop Med Hyg. 2005;99:803-808.
20. Kolaczinski JH, Reithinger R, Worku DT, Ocheng A, Kasimiro J, Kabatereine N, et al. Risk factors of visceral leishmaniasis in East Africa: a case-control study in Pokot territory of Kenya and Uganda. Int J Epidemiol. 2008;37:344-352.
21. Jafari S, Hajiabdolbaghi M, Mohebali M, Hajjaran H, Hashemian H. Disseminated leishmaniasis caused by Leishmania tropica in HIV-positive patients in the Islamic Republic of Iran. East Mediterr Health J. 2010;16:340-343.
22. Khandelwal K, Bumb RA, Mehta RD, Kaushal H, Lezama- Davila C, Salotra P, et al. A patient presenting with diffuse cutaneous leishmaniasis (DCL) as a first indicator of HIV infection in India. Am J Trop Med Hyg. 2011;85:64-65.
23. Soni P, Prasad N, Khandelwal K, Ghiya BC, Mehta RD, Bumb RA, et al. Unresponsive cutaneous leishmaniasis and HIV coinfection: report of three cases. Indian J Dermatol Venereol Leprol. 2011;77:251.