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Volumn 7, Issue 9, 2012, Pages

Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B100; CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEIN KINASE C GAMMA; SERINE; TAU PROTEIN; TRIACYLGLYCEROL;

EID: 84866645920     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046007     Document Type: Article
Times cited : (21)

References (40)
  • 2
    • 1842531662 scopus 로고    scopus 로고
    • Small dense low-density lipoprotein and carotid atherosclerosis in relation to vascular dementia
    • Watanabe T, Koba S, Kawamura M, Itokawa M, Idei T, et al. (2004) Small dense low-density lipoprotein and carotid atherosclerosis in relation to vascular dementia. Metabolism 53: 476-482.
    • (2004) Metabolism , vol.53 , pp. 476-482
    • Watanabe, T.1    Koba, S.2    Kawamura, M.3    Itokawa, M.4    Idei, T.5
  • 3
    • 72849117236 scopus 로고    scopus 로고
    • Low-density lipoprotein and apolipoprotein B: clinical use in patients with coronary heart disease
    • Cromwell WC, Barringer TA, (2009) Low-density lipoprotein and apolipoprotein B: clinical use in patients with coronary heart disease. Curr Cardiol Rep 11: 468-475.
    • (2009) Curr Cardiol Rep , vol.11 , pp. 468-475
    • Cromwell, W.C.1    Barringer, T.A.2
  • 4
    • 67349109736 scopus 로고    scopus 로고
    • Capillary injury in the ischemic brain of hyperlipidemic, apolipoprotein B-100 transgenic mice
    • Süle Z, Mracskó E, Bereczki E, Sántha M, Csont T, et al. (2009) Capillary injury in the ischemic brain of hyperlipidemic, apolipoprotein B-100 transgenic mice. Life Sci 84: 935-939.
    • (2009) Life Sci , vol.84 , pp. 935-939
    • Süle, Z.1    Mracskó, E.2    Bereczki, E.3    Sántha, M.4    Csont, T.5
  • 5
    • 70450219539 scopus 로고    scopus 로고
    • Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease
    • Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, et al. (2009) Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease. J Neurochem 111: 1275-1308.
    • (2009) J Neurochem , vol.111 , pp. 1275-1308
    • Martins, I.J.1    Berger, T.2    Sharman, M.J.3    Verdile, G.4    Fuller, S.J.5
  • 7
    • 12844269330 scopus 로고    scopus 로고
    • Is there a characteristic lipid profile in Alzheimer's disease?
    • Sabbagh M, Zahiri HR, Ceimo J, Cooper K, Gaul W, et al. (2004) Is there a characteristic lipid profile in Alzheimer's disease? Alzheimer's Dis 6: 585-589.
    • (2004) Alzheimer's Dis , vol.6 , pp. 585-589
    • Sabbagh, M.1    Zahiri, H.R.2    Ceimo, J.3    Cooper, K.4    Gaul, W.5
  • 8
    • 78650122129 scopus 로고    scopus 로고
    • Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease
    • Frisardi V, Solfrizzi V, Seripa D, Capurso C, Santamato A, et al. (2010) Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease. Ageing Res Rev 9: 399-417.
    • (2010) Ageing Res Rev , vol.9 , pp. 399-417
    • Frisardi, V.1    Solfrizzi, V.2    Seripa, D.3    Capurso, C.4    Santamato, A.5
  • 9
    • 0029784838 scopus 로고    scopus 로고
    • Amyloid beta-protein and the genetics of Alzheimer's disease
    • Selkoe DJ, (1996) Amyloid beta-protein and the genetics of Alzheimer's disease. J Biol Chem 271: 18295-18298.
    • (1996) J Biol Chem , vol.271 , pp. 18295-18298
    • Selkoe, D.J.1
  • 10
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ, (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297: 353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 11
    • 0003374626 scopus 로고    scopus 로고
    • Tau protein pathology in neurodegenerative diseases
    • Spillantini MG, Goedert M, (1998) Tau protein pathology in neurodegenerative diseases. Trends Neurosci 21: 428-433.
    • (1998) Trends Neurosci , vol.21 , pp. 428-433
    • Spillantini, M.G.1    Goedert, M.2
  • 12
    • 56249083216 scopus 로고    scopus 로고
    • Neurofibrillary degeneration in Alzheimer's disease: from molecular mechanisms to identification of drug targets
    • Pei JJ, Sjögren M, Winblad B, (2008) Neurofibrillary degeneration in Alzheimer's disease: from molecular mechanisms to identification of drug targets. Curr Opin Psychiatry 2: 555-561.
    • (2008) Curr Opin Psychiatry , vol.2 , pp. 555-561
    • Pei, J.J.1    Sjögren, M.2    Winblad, B.3
  • 15
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic BV, (2008) The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57: 178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 16
    • 33746358256 scopus 로고    scopus 로고
    • Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis
    • Bjelik A, Bereczki E, Gonda S, Juhász A, Rimanóczy A, et al. (2006) Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis. Neurochem Int 49: 393-400.
    • (2006) Neurochem Int , vol.49 , pp. 393-400
    • Bjelik, A.1    Bereczki, E.2    Gonda, S.3    Juhász, A.4    Rimanóczy, A.5
  • 17
    • 34548420672 scopus 로고    scopus 로고
    • Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice
    • Csont T, Bereczki E, Bencsik P, Fodor G, Görbe A, et al. (2007) Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice. Cardiovascular Res 76: 100-109.
    • (2007) Cardiovascular Res , vol.76 , pp. 100-109
    • Csont, T.1    Bereczki, E.2    Bencsik, P.3    Fodor, G.4    Görbe, A.5
  • 18
    • 0032716550 scopus 로고    scopus 로고
    • Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease
    • Yanagisawa M, Planel E, Ishiguro K, Fujita SC, (1999) Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease. FEBS Lett 461: 329-333.
    • (1999) FEBS Lett , vol.461 , pp. 329-333
    • Yanagisawa, M.1    Planel, E.2    Ishiguro, K.3    Fujita, S.C.4
  • 19
    • 0021923858 scopus 로고
    • Nile red: a selective fluorescent stain for intracellular lipid droplets
    • Greenspan P, Mayer PE, Fowler DS, (1985) Nile red: a selective fluorescent stain for intracellular lipid droplets. J Cell Biol 100: 965-973.
    • (1985) J Cell Biol , vol.100 , pp. 965-973
    • Greenspan, P.1    Mayer, P.E.2    Fowler, D.S.3
  • 20
    • 0022391125 scopus 로고
    • Application of Nile Red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: Comparison with Oil red O
    • Fowler SD, Greeanspan P, (1985) Application of Nile Red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: Comparison with Oil red O. J Histochem Cytochem 33: 833-836.
    • (1985) J Histochem Cytochem , vol.33 , pp. 833-836
    • Fowler, S.D.1    Greeanspan, P.2
  • 21
    • 0037258952 scopus 로고    scopus 로고
    • Kinetworks™ protein kinase multiblot analysis. Methods in Molecular Biology: Cancer Cell Signaling: Methods and Protocols (Terrian, D.M, ed.)
    • Pelech S, Sutter C, Zhang H, (2003) Kinetworks™ protein kinase multiblot analysis. Methods in Molecular Biology: Cancer Cell Signaling: Methods and Protocols (Terrian, D.M, ed.). Humana Press 218: 99-111.
    • (2003) Humana Press , vol.218 , pp. 99-111
    • Pelech, S.1    Sutter, C.2    Zhang, H.3
  • 22
    • 13844253258 scopus 로고    scopus 로고
    • Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons
    • Schmued LC, Stowers CC, Scallet AC, Xu L, (2005) Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain Res 1035: 24-31.
    • (2005) Brain Res , vol.1035 , pp. 24-31
    • Schmued, L.C.1    Stowers, C.C.2    Scallet, A.C.3    Xu, L.4
  • 23
    • 67651171781 scopus 로고    scopus 로고
    • Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance
    • Su Q, Tsai J, Xu E, Qiu W, Bereczki E, et al. (2009) Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology 50: 77-84.
    • (2009) Hepatology , vol.50 , pp. 77-84
    • Su, Q.1    Tsai, J.2    Xu, E.3    Qiu, W.4    Bereczki, E.5
  • 24
    • 0033872024 scopus 로고    scopus 로고
    • Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
    • Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, et al. (2000) Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol 157: 331-339.
    • (2000) Am J Pathol , vol.157 , pp. 331-339
    • Takeuchi, A.1    Irizarry, M.C.2    Duff, K.3    Saido, T.C.4    Hsiao Ashe, K.5
  • 25
    • 0028293315 scopus 로고
    • Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice
    • Callow MJ, Stoltzfus LJ, Lawn RM, Rubin EM, (1994) Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. Proc Natl Acad Sci USA 91: 2130-2134.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2130-2134
    • Callow, M.J.1    Stoltzfus, L.J.2    Lawn, R.M.3    Rubin, E.M.4
  • 27
    • 84862777666 scopus 로고    scopus 로고
    • ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models
    • Cramer PE, Cirrito JR, Wesson DW, Lee CY, Karlo JC, et al. (2012) ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models. Science 335: 1503-1506.
    • (2012) Science , vol.335 , pp. 1503-1506
    • Cramer, P.E.1    Cirrito, J.R.2    Wesson, D.W.3    Lee, C.Y.4    Karlo, J.C.5
  • 28
    • 0028902073 scopus 로고
    • Increased density of cortical apolipoprotein E immunoreactive neurons in rabbit brain after dietary administration of cholesterol
    • Sparks DL, Liu H, Gross DR, Scheff SW, (1995) Increased density of cortical apolipoprotein E immunoreactive neurons in rabbit brain after dietary administration of cholesterol. Neurosci Lett 187: 142-144.
    • (1995) Neurosci Lett , vol.187 , pp. 142-144
    • Sparks, D.L.1    Liu, H.2    Gross, D.R.3    Scheff, S.W.4
  • 30
    • 33846212717 scopus 로고    scopus 로고
    • Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
    • Wang JZ, Grundke-Iqbal I, Iqbal K, (2007) Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur J Neurosci 25: 59-68.
    • (2007) Eur J Neurosci , vol.25 , pp. 59-68
    • Wang, J.Z.1    Grundke-Iqbal, I.2    Iqbal, K.3
  • 31
    • 0032530145 scopus 로고    scopus 로고
    • Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules
    • Sengupta A, Kabat J, Novak M, Wu Q, Grundke-Iqbal I, et al. (1998) Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. Arch Biochem Biophys 357: 299-309.
    • (1998) Arch Biochem Biophys , vol.357 , pp. 299-309
    • Sengupta, A.1    Kabat, J.2    Novak, M.3    Wu, Q.4    Grundke-Iqbal, I.5
  • 32
    • 0040141570 scopus 로고    scopus 로고
    • Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments
    • Maas T, Eidenmüller J, Brandt R, (2000) Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments. J Biol Chem 275: 15733-15740.
    • (2000) J Biol Chem , vol.275 , pp. 15733-15740
    • Maas, T.1    Eidenmüller, J.2    Brandt, R.3
  • 33
    • 80052423497 scopus 로고    scopus 로고
    • Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons
    • Wang D, Yuen EY, Zhou Y, Yan Z, Xiang YK, (2011) Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons. J Biol Chem 286: 31852-31863.
    • (2011) J Biol Chem , vol.286 , pp. 31852-31863
    • Wang, D.1    Yuen, E.Y.2    Zhou, Y.3    Yan, Z.4    Xiang, Y.K.5
  • 34
    • 0032895651 scopus 로고    scopus 로고
    • Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation
    • Chui DH, Tanahashi H, Ozawa K, Ikeda S, Checler F, et al. (1999) Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. Nat Med 5: 560-564.
    • (1999) Nat Med , vol.5 , pp. 560-564
    • Chui, D.H.1    Tanahashi, H.2    Ozawa, K.3    Ikeda, S.4    Checler, F.5
  • 35
    • 43149088503 scopus 로고    scopus 로고
    • Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse
    • Chen Q, Nakajima A, Choi SH, Xiong X, Tang YP, (2008) Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse. J Neurosci Res 86: 1615-1625.
    • (2008) J Neurosci Res , vol.86 , pp. 1615-1625
    • Chen, Q.1    Nakajima, A.2    Choi, S.H.3    Xiong, X.4    Tang, Y.P.5
  • 36
    • 33747429095 scopus 로고    scopus 로고
    • Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency
    • Chan A, Shea TB, (2006) Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency. J Alzheimer's Dis 9: 399-405.
    • (2006) J Alzheimer's Dis , vol.9 , pp. 399-405
    • Chan, A.1    Shea, T.B.2
  • 38
    • 0036856263 scopus 로고    scopus 로고
    • Protein kinase C gamma (PKC gamma): function of neuron specific isotype
    • Saito N, Shirai Y, (2002) Protein kinase C gamma (PKC gamma): function of neuron specific isotype. J Biochem 132: 683-687.
    • (2002) J Biochem , vol.132 , pp. 683-687
    • Saito, N.1    Shirai, Y.2
  • 39
    • 0027745596 scopus 로고
    • Modified hippocampal long-term potentiation in PKC gamma-mutant mice
    • Abeliovich A, Chen C, Goda Y, Silva AJ, Stevens CF, et al. (1993) Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell 75: 1253-62.
    • (1993) Cell , vol.75 , pp. 1253-1262
    • Abeliovich, A.1    Chen, C.2    Goda, Y.3    Silva, A.J.4    Stevens, C.F.5
  • 40
    • 0027787664 scopus 로고
    • PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning
    • Abeliovich A, Paylor R, Chen C, Kim JJ, Wehner JM, et al. (1993) PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning. Cell 75: 1263-71.
    • (1993) Cell , vol.75 , pp. 1263-1271
    • Abeliovich, A.1    Paylor, R.2    Chen, C.3    Kim, J.J.4    Wehner, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.