-
1
-
-
33746909435
-
Lipid metabolism in cognitive decline and dementia
-
Panza F, D'Introno A, Colacicco AM, Capurso C, Pichichero G, et al. (2006) Lipid metabolism in cognitive decline and dementia. Brain Res Rev 51: 275-292.
-
(2006)
Brain Res Rev
, vol.51
, pp. 275-292
-
-
Panza, F.1
D'Introno, A.2
Colacicco, A.M.3
Capurso, C.4
Pichichero, G.5
-
2
-
-
1842531662
-
Small dense low-density lipoprotein and carotid atherosclerosis in relation to vascular dementia
-
Watanabe T, Koba S, Kawamura M, Itokawa M, Idei T, et al. (2004) Small dense low-density lipoprotein and carotid atherosclerosis in relation to vascular dementia. Metabolism 53: 476-482.
-
(2004)
Metabolism
, vol.53
, pp. 476-482
-
-
Watanabe, T.1
Koba, S.2
Kawamura, M.3
Itokawa, M.4
Idei, T.5
-
3
-
-
72849117236
-
Low-density lipoprotein and apolipoprotein B: clinical use in patients with coronary heart disease
-
Cromwell WC, Barringer TA, (2009) Low-density lipoprotein and apolipoprotein B: clinical use in patients with coronary heart disease. Curr Cardiol Rep 11: 468-475.
-
(2009)
Curr Cardiol Rep
, vol.11
, pp. 468-475
-
-
Cromwell, W.C.1
Barringer, T.A.2
-
4
-
-
67349109736
-
Capillary injury in the ischemic brain of hyperlipidemic, apolipoprotein B-100 transgenic mice
-
Süle Z, Mracskó E, Bereczki E, Sántha M, Csont T, et al. (2009) Capillary injury in the ischemic brain of hyperlipidemic, apolipoprotein B-100 transgenic mice. Life Sci 84: 935-939.
-
(2009)
Life Sci
, vol.84
, pp. 935-939
-
-
Süle, Z.1
Mracskó, E.2
Bereczki, E.3
Sántha, M.4
Csont, T.5
-
5
-
-
70450219539
-
Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease
-
Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, et al. (2009) Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease. J Neurochem 111: 1275-1308.
-
(2009)
J Neurochem
, vol.111
, pp. 1275-1308
-
-
Martins, I.J.1
Berger, T.2
Sharman, M.J.3
Verdile, G.4
Fuller, S.J.5
-
6
-
-
0033042287
-
Increased apolipoprotein B serum concentration in Alzheimer's disease
-
Caramelli P, Nitrini R, Maranhão R, Lourenço AC, Damasceno MC, et al. (1999) Increased apolipoprotein B serum concentration in Alzheimer's disease. Acta Neurol Scand 100: 61-63.
-
(1999)
Acta Neurol Scand
, vol.100
, pp. 61-63
-
-
Caramelli, P.1
Nitrini, R.2
Maranhão, R.3
Lourenço, A.C.4
Damasceno, M.C.5
-
7
-
-
12844269330
-
Is there a characteristic lipid profile in Alzheimer's disease?
-
Sabbagh M, Zahiri HR, Ceimo J, Cooper K, Gaul W, et al. (2004) Is there a characteristic lipid profile in Alzheimer's disease? Alzheimer's Dis 6: 585-589.
-
(2004)
Alzheimer's Dis
, vol.6
, pp. 585-589
-
-
Sabbagh, M.1
Zahiri, H.R.2
Ceimo, J.3
Cooper, K.4
Gaul, W.5
-
8
-
-
78650122129
-
Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease
-
Frisardi V, Solfrizzi V, Seripa D, Capurso C, Santamato A, et al. (2010) Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease. Ageing Res Rev 9: 399-417.
-
(2010)
Ageing Res Rev
, vol.9
, pp. 399-417
-
-
Frisardi, V.1
Solfrizzi, V.2
Seripa, D.3
Capurso, C.4
Santamato, A.5
-
9
-
-
0029784838
-
Amyloid beta-protein and the genetics of Alzheimer's disease
-
Selkoe DJ, (1996) Amyloid beta-protein and the genetics of Alzheimer's disease. J Biol Chem 271: 18295-18298.
-
(1996)
J Biol Chem
, vol.271
, pp. 18295-18298
-
-
Selkoe, D.J.1
-
10
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ, (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297: 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
11
-
-
0003374626
-
Tau protein pathology in neurodegenerative diseases
-
Spillantini MG, Goedert M, (1998) Tau protein pathology in neurodegenerative diseases. Trends Neurosci 21: 428-433.
-
(1998)
Trends Neurosci
, vol.21
, pp. 428-433
-
-
Spillantini, M.G.1
Goedert, M.2
-
12
-
-
56249083216
-
Neurofibrillary degeneration in Alzheimer's disease: from molecular mechanisms to identification of drug targets
-
Pei JJ, Sjögren M, Winblad B, (2008) Neurofibrillary degeneration in Alzheimer's disease: from molecular mechanisms to identification of drug targets. Curr Opin Psychiatry 2: 555-561.
-
(2008)
Curr Opin Psychiatry
, vol.2
, pp. 555-561
-
-
Pei, J.J.1
Sjögren, M.2
Winblad, B.3
-
13
-
-
41149149615
-
Abeta- degrading enzymes in Alzheimer's disease
-
Miners JS, Baig S, Palmer J, Palmer LE, Kehoe PG, et al. (2008) Abeta- degrading enzymes in Alzheimer's disease. Brain Pathol 18: 240-252.
-
(2008)
Brain Pathol
, vol.18
, pp. 240-252
-
-
Miners, J.S.1
Baig, S.2
Palmer, J.3
Palmer, L.E.4
Kehoe, P.G.5
-
14
-
-
60849109489
-
Astroglia in dementia and Alzheimer's disease
-
Rodríguez JJ, Olabarria M, Chvatal A, Verkhratsky A, (2009) Astroglia in dementia and Alzheimer's disease. Cell Death Differ 16: 378-385.
-
(2009)
Cell Death Differ
, vol.16
, pp. 378-385
-
-
Rodríguez, J.J.1
Olabarria, M.2
Chvatal, A.3
Verkhratsky, A.4
-
15
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic BV, (2008) The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57: 178-201.
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
16
-
-
33746358256
-
Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis
-
Bjelik A, Bereczki E, Gonda S, Juhász A, Rimanóczy A, et al. (2006) Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis. Neurochem Int 49: 393-400.
-
(2006)
Neurochem Int
, vol.49
, pp. 393-400
-
-
Bjelik, A.1
Bereczki, E.2
Gonda, S.3
Juhász, A.4
Rimanóczy, A.5
-
17
-
-
34548420672
-
Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice
-
Csont T, Bereczki E, Bencsik P, Fodor G, Görbe A, et al. (2007) Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice. Cardiovascular Res 76: 100-109.
-
(2007)
Cardiovascular Res
, vol.76
, pp. 100-109
-
-
Csont, T.1
Bereczki, E.2
Bencsik, P.3
Fodor, G.4
Görbe, A.5
-
18
-
-
0032716550
-
Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease
-
Yanagisawa M, Planel E, Ishiguro K, Fujita SC, (1999) Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease. FEBS Lett 461: 329-333.
-
(1999)
FEBS Lett
, vol.461
, pp. 329-333
-
-
Yanagisawa, M.1
Planel, E.2
Ishiguro, K.3
Fujita, S.C.4
-
19
-
-
0021923858
-
Nile red: a selective fluorescent stain for intracellular lipid droplets
-
Greenspan P, Mayer PE, Fowler DS, (1985) Nile red: a selective fluorescent stain for intracellular lipid droplets. J Cell Biol 100: 965-973.
-
(1985)
J Cell Biol
, vol.100
, pp. 965-973
-
-
Greenspan, P.1
Mayer, P.E.2
Fowler, D.S.3
-
20
-
-
0022391125
-
Application of Nile Red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: Comparison with Oil red O
-
Fowler SD, Greeanspan P, (1985) Application of Nile Red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: Comparison with Oil red O. J Histochem Cytochem 33: 833-836.
-
(1985)
J Histochem Cytochem
, vol.33
, pp. 833-836
-
-
Fowler, S.D.1
Greeanspan, P.2
-
21
-
-
0037258952
-
Kinetworks™ protein kinase multiblot analysis. Methods in Molecular Biology: Cancer Cell Signaling: Methods and Protocols (Terrian, D.M, ed.)
-
Pelech S, Sutter C, Zhang H, (2003) Kinetworks™ protein kinase multiblot analysis. Methods in Molecular Biology: Cancer Cell Signaling: Methods and Protocols (Terrian, D.M, ed.). Humana Press 218: 99-111.
-
(2003)
Humana Press
, vol.218
, pp. 99-111
-
-
Pelech, S.1
Sutter, C.2
Zhang, H.3
-
22
-
-
13844253258
-
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons
-
Schmued LC, Stowers CC, Scallet AC, Xu L, (2005) Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain Res 1035: 24-31.
-
(2005)
Brain Res
, vol.1035
, pp. 24-31
-
-
Schmued, L.C.1
Stowers, C.C.2
Scallet, A.C.3
Xu, L.4
-
23
-
-
67651171781
-
Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance
-
Su Q, Tsai J, Xu E, Qiu W, Bereczki E, et al. (2009) Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology 50: 77-84.
-
(2009)
Hepatology
, vol.50
, pp. 77-84
-
-
Su, Q.1
Tsai, J.2
Xu, E.3
Qiu, W.4
Bereczki, E.5
-
24
-
-
0033872024
-
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
-
Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, et al. (2000) Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol 157: 331-339.
-
(2000)
Am J Pathol
, vol.157
, pp. 331-339
-
-
Takeuchi, A.1
Irizarry, M.C.2
Duff, K.3
Saido, T.C.4
Hsiao Ashe, K.5
-
25
-
-
0028293315
-
Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice
-
Callow MJ, Stoltzfus LJ, Lawn RM, Rubin EM, (1994) Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. Proc Natl Acad Sci USA 91: 2130-2134.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2130-2134
-
-
Callow, M.J.1
Stoltzfus, L.J.2
Lawn, R.M.3
Rubin, E.M.4
-
27
-
-
84862777666
-
ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models
-
Cramer PE, Cirrito JR, Wesson DW, Lee CY, Karlo JC, et al. (2012) ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models. Science 335: 1503-1506.
-
(2012)
Science
, vol.335
, pp. 1503-1506
-
-
Cramer, P.E.1
Cirrito, J.R.2
Wesson, D.W.3
Lee, C.Y.4
Karlo, J.C.5
-
28
-
-
0028902073
-
Increased density of cortical apolipoprotein E immunoreactive neurons in rabbit brain after dietary administration of cholesterol
-
Sparks DL, Liu H, Gross DR, Scheff SW, (1995) Increased density of cortical apolipoprotein E immunoreactive neurons in rabbit brain after dietary administration of cholesterol. Neurosci Lett 187: 142-144.
-
(1995)
Neurosci Lett
, vol.187
, pp. 142-144
-
-
Sparks, D.L.1
Liu, H.2
Gross, D.R.3
Scheff, S.W.4
-
29
-
-
44649197748
-
ApoE promotes the proteolytic degradation of Abeta
-
Jiang Q, Lee CY, Mandrekar S, Wilkinson B, Cramer P, et al. (2008) ApoE promotes the proteolytic degradation of Abeta. Neuron 58: 681-693.
-
(2008)
Neuron
, vol.58
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
-
30
-
-
33846212717
-
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
-
Wang JZ, Grundke-Iqbal I, Iqbal K, (2007) Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur J Neurosci 25: 59-68.
-
(2007)
Eur J Neurosci
, vol.25
, pp. 59-68
-
-
Wang, J.Z.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
31
-
-
0032530145
-
Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules
-
Sengupta A, Kabat J, Novak M, Wu Q, Grundke-Iqbal I, et al. (1998) Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. Arch Biochem Biophys 357: 299-309.
-
(1998)
Arch Biochem Biophys
, vol.357
, pp. 299-309
-
-
Sengupta, A.1
Kabat, J.2
Novak, M.3
Wu, Q.4
Grundke-Iqbal, I.5
-
32
-
-
0040141570
-
Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments
-
Maas T, Eidenmüller J, Brandt R, (2000) Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments. J Biol Chem 275: 15733-15740.
-
(2000)
J Biol Chem
, vol.275
, pp. 15733-15740
-
-
Maas, T.1
Eidenmüller, J.2
Brandt, R.3
-
33
-
-
80052423497
-
Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons
-
Wang D, Yuen EY, Zhou Y, Yan Z, Xiang YK, (2011) Amyloid beta peptide-(1-42) induces internalization and degradation of beta2 adrenergic receptors in prefrontal cortical neurons. J Biol Chem 286: 31852-31863.
-
(2011)
J Biol Chem
, vol.286
, pp. 31852-31863
-
-
Wang, D.1
Yuen, E.Y.2
Zhou, Y.3
Yan, Z.4
Xiang, Y.K.5
-
34
-
-
0032895651
-
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation
-
Chui DH, Tanahashi H, Ozawa K, Ikeda S, Checler F, et al. (1999) Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. Nat Med 5: 560-564.
-
(1999)
Nat Med
, vol.5
, pp. 560-564
-
-
Chui, D.H.1
Tanahashi, H.2
Ozawa, K.3
Ikeda, S.4
Checler, F.5
-
35
-
-
43149088503
-
Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse
-
Chen Q, Nakajima A, Choi SH, Xiong X, Tang YP, (2008) Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse. J Neurosci Res 86: 1615-1625.
-
(2008)
J Neurosci Res
, vol.86
, pp. 1615-1625
-
-
Chen, Q.1
Nakajima, A.2
Choi, S.H.3
Xiong, X.4
Tang, Y.P.5
-
36
-
-
33747429095
-
Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency
-
Chan A, Shea TB, (2006) Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency. J Alzheimer's Dis 9: 399-405.
-
(2006)
J Alzheimer's Dis
, vol.9
, pp. 399-405
-
-
Chan, A.1
Shea, T.B.2
-
37
-
-
42449134064
-
Obesity and hypertriglyceridemia produce cognitive impairment
-
Farr SA, Yamada KA, Butterfield DA, Abdul HM, Xu L, et al. (2008) Obesity and hypertriglyceridemia produce cognitive impairment. Endocrinology 149: 2628-2636.
-
(2008)
Endocrinology
, vol.149
, pp. 2628-2636
-
-
Farr, S.A.1
Yamada, K.A.2
Butterfield, D.A.3
Abdul, H.M.4
Xu, L.5
-
38
-
-
0036856263
-
Protein kinase C gamma (PKC gamma): function of neuron specific isotype
-
Saito N, Shirai Y, (2002) Protein kinase C gamma (PKC gamma): function of neuron specific isotype. J Biochem 132: 683-687.
-
(2002)
J Biochem
, vol.132
, pp. 683-687
-
-
Saito, N.1
Shirai, Y.2
-
39
-
-
0027745596
-
Modified hippocampal long-term potentiation in PKC gamma-mutant mice
-
Abeliovich A, Chen C, Goda Y, Silva AJ, Stevens CF, et al. (1993) Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell 75: 1253-62.
-
(1993)
Cell
, vol.75
, pp. 1253-1262
-
-
Abeliovich, A.1
Chen, C.2
Goda, Y.3
Silva, A.J.4
Stevens, C.F.5
-
40
-
-
0027787664
-
PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning
-
Abeliovich A, Paylor R, Chen C, Kim JJ, Wehner JM, et al. (1993) PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning. Cell 75: 1263-71.
-
(1993)
Cell
, vol.75
, pp. 1263-1271
-
-
Abeliovich, A.1
Paylor, R.2
Chen, C.3
Kim, J.J.4
Wehner, J.M.5
|