Limitations of postmarketing surveillance in the analysis of risk of pregnancy loss associated with maternal mefloquine exposure

Clinical Infectious Diseases

Volumn 55, Issue 8, 2012, Pages 1167-1168

  Nevin, Remington Lee ^a  

^a Bayne Jones Army Community Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEFLOQUINE; PYRIMETHAMINE PLUS SULFADOXINE;

ENVIRONMENTAL EXPOSURE; FETUS OUTCOME; HUMAN; LETTER; POSTMARKETING SURVEILLANCE; PREGNANCY OUTCOME; PRIORITY JOURNAL; RISK ASSESSMENT; SPONTANEOUS ABORTION; STILLBIRTH;

ABNORMALITIES, DRUG-INDUCED; ABORTION, SPONTANEOUS; ANTIMALARIALS; CHEMOPREVENTION; FEMALE; HUMANS; MALARIA; MEFLOQUINE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

EID: 84866639309     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cis601     Document Type: Letter

References (10)

1. Schlagenhauf P, Blumentals WA, Suter P, et al. Pregnancy and fetal outcomes after exposure to mefloquine in the pre-and periconception period and during pregnancy. Clin Infect Dis 2012; 54:e124-31.
2. Vanhauwere B, Maradit H, Kerr L. Postmarketing surveillance of prophylactic mefloquine (Lariam) use in pregnancy. Am J Trop Med Hyg 1998; 58:17-21.
3. Nosten F, ter Kuile F, Maelankiri L, et al. Mefloquine prophylaxis prevents malaria during pregnancy: a double-blind, placebocontrolled study. J Infect Dis 1994; 169: 595-603.
4. Nosten F, Vincenti M, Simpson J, et al. The effects of mefloquine treatment in pregnancy. Clin Infect Dis 1999; 28:808-15.
5. Phillips-Howard PA, Steffen R, Kerr L, et al. Safety of mefloquine and other antimalarial agents in the first trimester of pregnancy. J Travel Med 1998; 5:121-6.
6. Smoak BL, Writer JV, Keep LW, Cowan J, Chantelois JL. The effects of inadvertent exposure of mefloquine chemoprophylaxis on pregnancy outcomes and infants of US army servicewomen. J Infect Dis 1997; 176: 831-3.
7. Rowland M, Nosten F. Malaria epidemiology and control in refugee camps and complex emergencies. Ann Trop Med Parasitol 2001; 95:741-54.
8. Briand V, Bottero J, Noël H, et al. Intermittent treatment for the prevention of malaria during pregnancy in Benin: a randomized, open-label equivalence trial comparing sulfadoxine-pyrimethamine with mefloquine. J Infect Dis 2009; 200:991-1001.
9. World Health Organization. A strategic framework for malaria prevention and control during pregnancy in the African region. Available at: http://whqlibdoc.who.int/afro/2004/AFR-MAL-04.01.pdf. Accessed 10 May 2012.
10. Nevin RL. Mefloquine blockade of connexin 43 (Cx43) and risk of pregnancy loss. Placenta 2011; 32:712.