Histologic characterization of human ear ossicles for the development of tissue-engineered replacements

Otology and Neurotology

Volumn 33, Issue 8, 2012, Pages 1458-1468

  D'Alessandro, Delfo ^a   Danti, Serena ^a   De Vito, Andrea ^a,b   Forli, Francesca ^a   Bruschini, Luca ^a   Berrettini, Stefano ^a,b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

Author keywords

Ear histology; Mesenchymal stem cells; Ossicular chain; Partial ossicular replacement prosthesis; Scaffold; Tissue engineering

Indexed keywords

BIOLOGICAL MARKER; COLLAGEN; FORMALDEHYDE; GLYCOPROTEIN; SCLEROPROTEIN; TISSUE SCAFFOLD;

ARTICLE; AUDITORY OSSICLE; CADAVER; EXTRACELLULAR MATRIX; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; MIDDLE EAR PROSTHESIS; MIDDLE EAR RECONSTRUCTION; PROSTHESIS; REGENERATION; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TISSUE FIXATION; ULTRASTRUCTURE;

BIOLOGICAL MARKERS; CADAVER; COLLAGEN; EAR OSSICLES; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FORMALDEHYDE; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON, SCANNING; OSSICULAR PROSTHESIS; OSSICULAR REPLACEMENT; PROSTHESIS DESIGN; REGENERATION; TISSUE ENGINEERING; TISSUE FIXATION; TISSUE SCAFFOLDS;

EID: 84866628159     PISSN: 15317129     EISSN: 15374505     Source Type: Journal    
DOI: 10.1097/MAO.0b013e31826a527d     Document Type: Article

References (28)

1. Slater PW, Rizer FM, Schuring AG, Lippy WH. Practical use of total and partial ossicular replacement prostheses in ossiculoplasty. Laryngoscope 1997;107:1193-8.
2. Bojrab DI, Causse JB, Battista RA, Vincent R, Gratacap B, Vandeventer G. Ossiculoplasty with composite prostheses. Overview and analysis. Otolaryngol Clin North Am 1994;27:759-76.
3. Nguyen DQ, Lavieille JP, Schmerber S. Failure rate and revision surgery in ossiculoplasty with Kurz titanium prosthesis. Rev Laryngol Otol Rhinol (Bord) 2004;125:157-62.
4. Sellari-Franceschini S, Piragine F, Bruschini P, Berrettini S. TORPs and PORPs: causes of failure. Am J Otol 1987;8:551-2.
5. Quaranta N, Fernandez-Vega Feijoo S, Piazza F, Zini C. Closed tympanoplasty in cholesteatoma surgery: long-term (10 years) hearing results using cartilage ossiculoplasty. Eur Arch Otorhinolaryngol 2001;258:20-4.
6. Ferrero V, Bussi M, Giordano L, Cavalot AL, Albera R. Functional results in the reconstruction of the ossicular chain in partial or total atrophy of the incus. Comparison between reconstruction using a moulded incus and hydroxyapatite PORP. Acta Otorhinolaryngol Ital 2000;20:159-64.
7. Pyle GM. Ossicular sculpting for conductive hearing loss. Op Tech Otolaryngol 2003;14:237-42.
8. Danti S, Stefanini C, D'Alessandro D, et al. Novel biological/biohybrid prostheses for the ossicular chain: fabrication feasibility and preliminary functional characterization. Biomed Microdevices 2009; 11:783-93.
9. Berrettini S, Bruschini L, Stefanini C, D'Alessandro D, D'Acunto M, Danti S. Good manufacturing practices-grade preformed ossicular prostheses from banked bone via computer numerically controlled micromilling. Ann Otol Rhinol Laryngol 2011;120:9-16.
10. Dormer KJ, Gan RZ. Biomaterials for implantable middle ear hearing devices. Otolaryngol Clin North Am 2001;34:289-97.
11. Danti S, D'Alessandro D, Pietrabissa A, Petrini M, Berrettini S. Development of tissue-engineered substitutes of the ear ossicles: PORP-shaped poly(propylene fumarate)-based scaffolds cultured with human mesenchymal stromal cells. J BiomedMater Res A 2010; 92:1343-56.
12. Ingber D, Mow V, Butler D, et al. Tissue engineering and developmental biology: going biomimetic. Tissue Eng 2006;12:3265-83.
13. Graysona W, Martensa T, Enga G, Radisic M, Vunjak-Novakovic G. Biomimetic approach to tissue engineering. Stem Cell Devel Biol 2009;20:665-73.
14. Pham QP, Kasper FK, Scott Baggett L, Raphael RM, Jansen JA, Mikos AG. The influence of an in vitro generated bone-like extracellular matrix on osteoblastic gene expression of marrow stromal cells. Biomaterials 2008;29:2729-39.
15. Datta N, Pham QP, Sharma U, Sikavitsas VI, Jansen JA, Mikos AG. In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci U S A 2006;103:2488-93.
16. Sarrat R, Torres A, Guzman AG, Lostalé F, Whyte J. Functional structure of human auditory ossicles. Acta Anat (Basel) 1992;144: 189-95.
17. Javia LR, Ruckenstein MJ. Ossiculoplasty. Otolaryngol Clin North Am 2006;39:1177-89.
18. Gillanders DA, Cambon KG, Doyle PJ. Porps, torps, and homografts in tympanoplasty. J Otolaryngol 1980;9:169-76.
19. Whyte J, Cisneros A, Yus C, et al. Development of the dynamic structure (force lines) of the middle ear ossicles in human foetuses. Histol Histopathol 2008;23:1049-60.
20. Dornelles C, Rosito LP, Meurer L, Costa SS, Argenta A, Alves SL. Hystology findings' correlation between the ossicular chain in the transoperative and cholesteatomas. Braz J Otorhinolaryngol 2007; 73:738-43.
21. Yetiser S, Hidir Y, Birkent H, Satar B, Durmaz A. Traumatic ossicular dislocations: etiology and management. Am J Otolaryngol 2008;29:31-6.
22. Unur E, Ülger H, Ekinci N. Morphometrical and morphological variations of middle ear ossicles in the newborn. Erciyes Med J 2002;24:57-63.
23. Yokoyama T, Iino Y, Kakizaki K, Murakami Y. Human temporal bone study on the postnatal ossification process of auditory ossicles. Laryngoscope 1999;109:927-30.
24. Lim DJ, Robinson M, Saunders WH. Morphologic and immunohistochemical observation of otosclerotic stapes: a preliminary study. Am J Otolaryngol 1987;8:282-95.
25. Niedermeyer HP, Becker ET, Arnold W. Expression of collagens in the otosclerotic bone. Adv Otorhinolaryngol 2007;65:45-9.
26. Lian J, Stein G. Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation. Iowa Orthop J 1995;15:118-40.
27. Olsen BR, Reginato AM, Wang W. Bone development. Annu Rev Cell Dev Biol 2000;16:191-220.
28. Aubin JE. Advances in the osteoblast lineage. Biochem Cell Biol 1998;76:899-910.