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Volumn 92, Issue 4, 2012, Pages 419-421

In search of physiologically based distribution volume estimates for macromolecules

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BLOOD CLOTTING FACTOR 9; INSULIN; TRASTUZUMAB EMTANSINE;

EID: 84866626729     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.156     Document Type: Review
Times cited : (6)

References (10)
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    • Semi-mechanistic Population Pharmacokinetic Model of Multivalent Trastuzumab Emtansine in Patients with Metastatic Breast Cancer
    • Chudasama, V.L. et al. Semi-mechanistic Population Pharmacokinetic Model of Multivalent Trastuzumab Emtansine in Patients with Metastatic Breast Cancer. Clin. Pharmacol. Ther. 92, 520-527 (2012).
    • (2012) Clin. Pharmacol. Ther. , vol.92 , pp. 520-527
    • Chudasama, V.L.1
  • 2
    • 54249138516 scopus 로고    scopus 로고
    • Monoclonal antibody pharmacokinetics and pharmacodynamics
    • Wang, W., Wang, E.Q. & Balthasar, J.P. Monoclonal antibody pharmacokinetics and pharmacodynamics. Clin. Pharmacol. Ther. 84, 548-558 (2008).
    • (2008) Clin. Pharmacol. Ther. , vol.84 , pp. 548-558
    • Wang, W.1    Wang, E.Q.2    Balthasar, J.P.3
  • 3
    • 0038825183 scopus 로고    scopus 로고
    • The pharmacokinetics of clotting factor therapy
    • Berntorp, P. & Björkman, S. The pharmacokinetics of clotting factor therapy. Haemophilia 9, 353-359 (2003).
    • (2003) Haemophilia , vol.9 , pp. 353-359
    • Berntorp, P.1    Björkman, S.2
  • 6
    • 0000937152 scopus 로고
    • 131-albumin catabolism and distribution in normal young male adults
    • 131-albumin catabolism and distribution in normal young male adults. J. Clin. Invest. 41, 1312-1333 (1962).
    • (1962) J. Clin. Invest. , vol.41 , pp. 1312-1333
    • Beeken, W.L.1
  • 7
    • 84864280808 scopus 로고    scopus 로고
    • Population pharmacokinetics of plasma-derived factor IX in adult patients with haemophilia B: Implications for dosing in prophylaxis
    • Björkman, S. & Åhlén, V. Population pharmacokinetics of plasma-derived factor IX in adult patients with haemophilia B: implications for dosing in prophylaxis. Eur. J. Clin. Pharmacol. 68, 969-977 (2012).
    • (2012) Eur. J. Clin. Pharmacol. , vol.68 , pp. 969-977
    • Björkman, S.1    Åhlén, V.2
  • 8
    • 0027469701 scopus 로고
    • 2-urea kinetics in humans
    • 2-urea kinetics in humans. Clin. Pharmacol. Ther. 53, 419-425 (1993).
    • (1993) Clin. Pharmacol. Ther. , vol.53 , pp. 419-425
    • Odeh, Y.K.1
  • 9
    • 0028365342 scopus 로고
    • Pharmacokinetics of Factor IX in patients with haemophilia B. Methodological aspects and physiological interpretation
    • Björkman, S., Carlsson, M. & Berntorp, E. Pharmacokinetics of Factor IX in patients with haemophilia B. Methodological aspects and physiological interpretation. Eur. J. Clin. Pharmacol. 46, 325-332 (1994).
    • (1994) Eur. J. Clin. Pharmacol. , vol.46 , pp. 325-332
    • Björkman, S.1    Carlsson, M.2    Berntorp, E.3
  • 10
    • 0024244938 scopus 로고
    • General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment
    • Nakashima, E., Benet, L.Z. General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment. J. Pharmacokinet. Biopharm. 16, 475-492 (1988).
    • (1988) J. Pharmacokinet. Biopharm. , vol.16 , pp. 475-492
    • Nakashima, E.1    Benet, L.Z.2


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