Transglutaminase-mediated transamidation of serotonin, dopamine and noradrenaline to fibronectin: Evidence for a general mechanism of monoaminylation

FEBS Letters

Volumn 586, Issue 19, 2012, Pages 3421-3428

  Hummerich, René ^a   Thumfart, Jörg Oliver ^a   Findeisen, Peter ^a   Bartsch, Dusan ^a   Schloss, Patrick ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Fibronectin; Monoaminylation; Serotonylation; Transamidation; Transglutaminase

Indexed keywords

BOVINE SERUM ALBUMIN; DANSYLCADAVERINE; DOPAMINE; FIBRONECTIN; NORADRENALIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SEROTONIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; IC 50; INHIBITION KINETICS; MASS SPECTROMETRY; MOLECULAR INTERACTION; MONOAMINYLATION; PRIORITY JOURNAL; PROTEIN BINDING; SEROTONYLATION; TRANSAMIDATION;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELL LINE; DOPAMINE; FIBRONECTINS; GLUTAMINE; GUINEA PIGS; KINETICS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NOREPINEPHRINE; RATS; SEROTONIN; SERUM ALBUMIN, BOVINE; TANDEM MASS SPECTROMETRY; TRANSGLUTAMINASES;

EID: 84866626092     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.07.062     Document Type: Article

References (17)

1. R. Szasz, and G.L. Dale COAT platelets Curr. Opin. Hematol. 10 2003 351 355
2. G.L. Dale Coated-platelets: an emerging component of the procoagulant response J. Thromb. Haemost. 3 2005 2185 2192
3. R. Szasz, and G.L. Dale Thrombospondin and fibrinogen bind serotonin-derivatized proteins on COAT-platelets Blood 100 2002 2827 2831
4. G.L. Dale, P. Friese, P. Batar, S.F. Hamilton, G.L. Reed, K.W. Jackson, K.J. Clemetson, and L. Alberio Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface Nature 415 2002 175 179
5. N. Paulmann Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation PLoS Biol. 7 2009 e1000229
6. D.J. Walther Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release Cell 115 2003 851 862
7. R. Hummerich, and P. Schloss Serotonin - more than a neurotransmitter: transglutaminase-mediated serotonylation of C6 glioma cells and fibronectin Neurochem. Int. 57 2010 67 75
8. S.W. Watts, J.R. Priestley, and J.M. Thompson Serotonylation of vascular proteins important to contraction PLoS ONE 4 2009 e5682
9. S.M. Gillet, R.A. Chica, J.W. Keillor, and J.N. Pelletier Expression and rapid purification of highly active hexahistidine-tagged guinea pig liver transglutaminase Protein Expr. Purif. 33 2004 256 264
10. J.E. Folk, and P.W. Cole Transglutaminase: mechanistic features of the active site as determined by kinetic and inhibitor studies Biochim. Biophys. Acta 122 1966 244 264
11. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
12. A. Pandey, J.S. Andersen, and M. Mann Use of mass spectrometry to study signaling pathways Sci. STKE 2000 2000 PL1
13. C. Esposito, and I. Caputo Mammalian transglutaminases. Identification of substrates as a key to physiological function and physiopathological relevance FEBS J. 272 2005 615 631
14. L. Fesus, and M. Piacentini Transglutaminase 2: an enigmatic enzyme with diverse functions Trends Biochem. Sci. 27 2002 534 539
15. K.B. Johnson Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2 Am. J. Physiol. Heart Circ. Physiol. 302 2012 H1355 H1366
16. K.B. Johnson, J.M. Thompson, and S.W. Watts Modification of proteins by norepinephrine is important for vascular contraction Front. Physiol. 1 2010 131
17. D.J. Walther, S. Stahlberg, and J. Vowinckel Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases FEBS J. 278 2011 4740 4755