메뉴 건너뛰기




Volumn 4 S, Issue 3, 2012, Pages 810-818

Roles of microRNAs in cancer stem cells

Author keywords

Cancer stem cells; MicroRNA; Review; Stem cells; Tumorigenesis

Indexed keywords

BETA CATENIN; BIOLOGICAL MARKER; BMI1 PROTEIN; HIGH MOBILITY GROUP A2 PROTEIN; MICRORNA; NOTCH RECEPTOR; WNT PROTEIN; UNTRANSLATED RNA;

EID: 84866604492     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (79)
  • 2
    • 38449099002 scopus 로고    scopus 로고
    • Mammary stem and progenitor cell regulation
    • Stem Cells and Cancer
    • R. I. Glazer, X. Wang, H. Yuan and Y. Yin: Mammary stem and progenitor cell regulation. Cancer Biomark, 3(4-5), 171-81 (2007) (Pubitemid 351492642)
    • (2007) Cancer Biomarkers , vol.3 , Issue.4-5 , pp. 171-181
    • Glazer, R.I.1    Wang, X.2    Yuan, H.3    Yin, Y.4
  • 3
    • 78149316177 scopus 로고    scopus 로고
    • Epigenetic control of embryonic stem cell fate
    • N. S. Christophersen and K. Helin: Epigenetic control of embryonic stem cell fate. J Exp Med, 207(11), 2287-95 (2010)
    • (2010) J Exp Med , vol.207 , Issue.11 , pp. 2287-2295
    • Christophersen, N.S.1    Helin, K.2
  • 6
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • N. Xu, T. Papagiannakopoulos, G. Pan, J. A. Thomson and K. S. Kosik: MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell, 137(4), 647-58 (2009)
    • (2009) Cell , vol.137 , Issue.4 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 7
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells - Perspectives on current status and future directions: AACR workshop on cancer stem cells
    • DOI 10.1158/0008-5472.CAN-06-3126
    • M. F. Clarke, J. E. Dick, P. B. Dirks, C. J. Eaves, C. H. Jamieson, D. L. Jones, J. Visvader, I. L. Weissman and G. M. Wahl: Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res, 66(19), 9339-44 (2006) (Pubitemid 44623625)
    • (2006) Cancer Research , vol.66 , Issue.19 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.M.5    Jones, D.L.6    Visvader, J.7    Weissman, I.L.8    Wahl, G.M.9
  • 9
    • 0027751663 scopus 로고
    • The C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • DOI 10.1016/0092-8674(93)90529-Y
    • R. C. Lee, R. L. Feinbaum and V. Ambros: The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75(5), 843-54 (1993) (Pubitemid 24014542)
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 10
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • DOI 10.1126/science.1064921
    • M. Lagos-Quintana, R. Rauhut, W. Lendeckel and T. Tuschl: Identification of novel genes coding for small expressed RNAs. Science, 294(5543), 853-8 (2001) (Pubitemid 33032103)
    • (2001) Science , vol.294 , Issue.5543 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 11
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • DOI 10.1038/sj.emboj.7600385
    • Y. Lee, M. Kim, J. Han, K. H. Yeom, S. Lee, S. H. Baek and V. N. Kim: MicroRNA genes are transcribed by RNA polymerase II. Embo J, 23(20), 4051-60 (2004) (Pubitemid 39472426)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.-H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 12
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • J. Krol, I. Loedige and W. Filipowicz: The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet, 11(9), 597-610 (2010)
    • (2010) Nat Rev Genet , vol.11 , Issue.9 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 13
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • DOI 10.1261/rna.7135204
    • X. Cai, C. H. Hagedorn and B. R. Cullen: Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. Rna, 10(12), 1957-66 (2004) (Pubitemid 39557833)
    • (2004) RNA , vol.10 , Issue.12 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 14
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • DOI 10.1101/gad.1262504
    • J. Han, Y. Lee, K. H. Yeom, Y. K. Kim, H. Jin and V. N. Kim: The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev, 18(24), 3016-27 (2004) (Pubitemid 39658171)
    • (2004) Genes and Development , vol.18 , Issue.24 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.-H.3    Kim, Y.-K.4    Jin, H.5    Kim, V.N.6
  • 15
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • DOI 10.1101/gad.1158803
    • R. Yi, Y. Qin, I. G. Macara and B. R. Cullen: Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev, 17(24), 3011-6 (2003) (Pubitemid 38040764)
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 16
    • 27144550559 scopus 로고    scopus 로고
    • TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
    • DOI 10.1038/sj.embor.7400509, PII 7400509
    • A. D. Haase, L. Jaskiewicz, H. Zhang, S. Laine, R. Sack, A. Gatignol and W. Filipowicz: TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep, 6(10), 961-7 (2005) (Pubitemid 41521952)
    • (2005) EMBO Reports , vol.6 , Issue.10 , pp. 961-967
    • Haase, A.D.1    Jaskiewicz, L.2    Zhang, H.3    Laine, S.4    Sack, R.5    Gatignol, A.6    Filipowicz, W.7
  • 17
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • DOI 10.1038/ncb1274
    • J. Liu, M. A. Valencia-Sanchez, G. J. Hannon and R. Parker: MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol, 7(7), 719-23 (2005) (Pubitemid 40975754)
    • (2005) Nature Cell Biology , vol.7 , Issue.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 18
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C elegans
    • DOI 10.1016/0092-8674(93)90530-4
    • B. Wightman, I. Ha and G. Ruvkun: Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell, 75(5), 855-62 (1993) (Pubitemid 24014543)
    • (1993) Cell , vol.75 , Issue.5 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 24
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • DOI 10.1158/0008-5472.CAN-05-0137
    • J. A. Chan, A. M. Krichevsky and K. S. Kosik: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res, 65(14), 6029-33 (2005) (Pubitemid 40994386)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 25
    • 33744521896 scopus 로고    scopus 로고
    • Involvement of human micro-rna in growth and response to chemotherapy in human cholangiocarcinoma cell lines
    • DOI 10.1053/j.gastro.2006.02.057, PII S0016508506007360
    • F. Meng, R. Henson, M. Lang, H. Wehbe, S. Maheshwari, J. T. Mendell, J. Jiang, T. D. Schmittgen and T. Patel: Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines. Gastroenterology, 130(7), 2113-29 (2006) (Pubitemid 43816961)
    • (2006) Gastroenterology , vol.130 , Issue.7 , pp. 2113-2129
    • Meng, F.1    Henson, R.2    Lang, M.3    Wehbe, H.4    Maheshwari, S.5    Mendell, J.T.6    Jiang, J.7    Schmittgen, T.D.8    Patel, T.9
  • 28
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • DOI 10.1038/nature03677
    • K. A. O'Donnell, E. A. Wentzel, K. I. Zeller, C. V. Dang and J. T. Mendell: c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 435(7043), 839-43 (2005) (Pubitemid 40839736)
    • (2005) Nature , vol.435 , Issue.7043 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3    Dang, C.V.4    Mendell, J.T.5
  • 30
    • 43449100341 scopus 로고    scopus 로고
    • REST maintains self-renewal and pluripotency of embryonic stem cells
    • DOI 10.1038/nature06863, PII NATURE06863
    • S. K. Singh, M. N. Kagalwala, J. Parker-Thornburg, H. Adams and S. Majumder: REST maintains self-renewal and pluripotency of embryonic stem cells. Nature, 453(7192), 223-7 (2008) (Pubitemid 351667975)
    • (2008) Nature , vol.453 , Issue.7192 , pp. 223-227
    • Singh, S.K.1    Kagalwala, M.N.2    Parker-Thornburg, J.3    Adams, H.4    Majumder, S.5
  • 32
    • 22144444302 scopus 로고    scopus 로고
    • The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage
    • DOI 10.1038/nsmb936, PII NSMB936
    • A. D. Scadden: The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage. Nat Struct Mol Biol, 12(6), 489-96 (2005) (Pubitemid 43085878)
    • (2005) Nature Structural and Molecular Biology , vol.12 , Issue.6 , pp. 489-496
    • Scadden, A.D.J.1
  • 33
    • 34547629436 scopus 로고    scopus 로고
    • RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer - TRBP complex
    • DOI 10.1038/sj.embor.7401011, PII 7401011
    • Y. Kawahara, B. Zinshteyn, T. P. Chendrimada, R. Shiekhattar and K. Nishikura: RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex. EMBO Rep, 8(8), 763-9 (2007) (Pubitemid 47202456)
    • (2007) EMBO Reports , vol.8 , Issue.8 , pp. 763-769
    • Kawahara, Y.1    Zinshteyn, B.2    Chendrimada, T.P.3    Shiekhattar, R.4    Nishikura, K.5
  • 34
    • 75649129754 scopus 로고    scopus 로고
    • Sorting of Drosophila small silencing RNAs partitions microRNA strands into the RNA interference pathway
    • M. Ghildiyal, J. Xu, H. Seitz, Z. Weng and P. D. Zamore: Sorting of Drosophila small silencing RNAs partitions microRNA strands into the RNA interference pathway. Rna, 16(1), 43-56 (2010)
    • (2010) RNA , vol.16 , Issue.1 , pp. 43-56
    • Ghildiyal, M.1    Xu, J.2    Seitz, H.3    Weng, Z.4    Zamore, P.D.5
  • 35
    • 34250190230 scopus 로고    scopus 로고
    • Cancer initiation and progression: Involvement of stem cells and the microenvironment
    • DOI 10.1016/j.bbcan.2007.01.001, PII S0304419X07000029
    • B. B. Tysnes and R. Bjerkvig: Cancer initiation and progression: involvement of stem cells and the microenvironment. Biochim Biophys Acta, 1775(2), 283-97 (2007) (Pubitemid 46901154)
    • (2007) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1775 , Issue.2 , pp. 283-297
    • Tysnes, B.B.1    Bjerkvig, R.2
  • 36
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • R. Pardal, M. F. Clarke and S. J. Morrison: Applying the principles of stem-cell biology to cancer. Nat Rev Cancer, 3(12), 895-902 (2003) (Pubitemid 37500174)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 37
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • T. Reya, S. J. Morrison, M. F. Clarke and I. L. Weissman: Stem cells, cancer, and cancer stem cells. Nature, 414(6859), 105-11 (2001) (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 38
    • 4043170088 scopus 로고    scopus 로고
    • Epithelial polarity and proliferation control: Links from the Drosophila neoplastictumor suppressors
    • DOI 10.1101/gad.1211604
    • D. Bilder: Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev, 18(16), 1909-25 (2004) (Pubitemid 39071572)
    • (2004) Genes and Development , vol.18 , Issue.16 , pp. 1909-1925
    • Bilder, D.1
  • 39
    • 37449027604 scopus 로고    scopus 로고
    • MicroRNA and stem cell function
    • DOI 10.1007/s00441-007-0530-3
    • S. Hatfield and H. Ruohola-Baker: microRNA and stem cell function. Cell Tissue Res, 331(1), 57-66 (2008) (Pubitemid 50001378)
    • (2008) Cell and Tissue Research , vol.331 , Issue.1 , pp. 57-66
    • Hatfield, S.1    Ruohola-Baker, H.2
  • 42
    • 67650810301 scopus 로고    scopus 로고
    • Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs
    • V. Kashyap, N. C. Rezende, K. B. Scotland, S. M. Shaffer, J. L. Persson, L. J. Gudas and N. P. Mongan: Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev, 18(7), 1093-108 (2009)
    • (2009) Stem Cells Dev , vol.18 , Issue.7 , pp. 1093-1108
    • Kashyap, V.1    Rezende, N.C.2    Scotland, K.B.3    Shaffer, S.M.4    Persson, J.L.5    Gudas, L.J.6    Mongan, N.P.7
  • 43
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
    • Y. Tay, J. Zhang, A. M. Thomson, B. Lim and I. Rigoutsos: MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature, 455(7216), 1124-8 (2008)
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3    Lim, B.4    Rigoutsos, I.5
  • 47
    • 8844265508 scopus 로고    scopus 로고
    • Epigenetic regulation of cellular memory by the polycomb and trithorax group proteins
    • DOI 10.1146/annurev.genet.38.072902.091907
    • L. Ringrose and R. Paro: Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet, 38, 413-43 (2004) (Pubitemid 40013734)
    • (2004) Annual Review of Genetics , vol.38 , pp. 413-443
    • Ringrose, L.1    Paro, R.2
  • 48
    • 33745633569 scopus 로고    scopus 로고
    • CIMPle origin for promoter hypermethylation in colorectal cancer?
    • DOI 10.1038/ng0706-738, PII N0706738
    • K. Schuebel, W. Chen and S. B. Baylin: CIMPle origin for promoter hypermethylation in colorectal cancer? Nat Genet, 38(7), 738-40 (2006) (Pubitemid 43982544)
    • (2006) Nature Genetics , vol.38 , Issue.7 , pp. 738-740
    • Schuebel, K.1    Chen, W.2    Baylin, S.B.3
  • 51
    • 34249907279 scopus 로고    scopus 로고
    • ShRNA Knockdown of Bmi-1 Reveals a Critical Role for p21-Rb Pathway in NSC Self-Renewal during Development
    • DOI 10.1016/j.stem.2007.04.001, PII S1934590907000045
    • C. A. Fasano, J. T. Dimos, N. B. Ivanova, N. Lowry, I. R. Lemischka and S. Temple: shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell, 1(1), 87-99 (2007) (Pubitemid 46865801)
    • (2007) Cell Stem Cell , vol.1 , Issue.1 , pp. 87-99
    • Fasano, C.A.1    Dimos, J.T.2    Ivanova, N.B.3    Lowry, N.4    Lemischka, I.R.5    Temple, S.6
  • 52
    • 36248953716 scopus 로고    scopus 로고
    • Mammary stem cells and breast cancer - Role of notch signalling
    • DOI 10.1007/s12015-007-0023-5, PII SCR32169
    • G. Farnie and R. B. Clarke: Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev, 3(2), 169-75 (2007) (Pubitemid 350129719)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 169-175
    • Farnie, G.1    Clarke, R.B.2
  • 54
    • 45749149045 scopus 로고    scopus 로고
    • Cancer stem cells and survival pathways
    • D. Hambardzumyan, O. J. Becher and E. C. Holland: Cancer stem cells and survival pathways. Cell Cycle, 7(10), 1371-8 (2008) (Pubitemid 351872575)
    • (2008) Cell Cycle , vol.7 , Issue.10 , pp. 1371-1378
    • Hambardzumyan, D.1    Becher, O.J.2    Holland, E.C.3
  • 58
    • 78650126775 scopus 로고    scopus 로고
    • Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells
    • B. Kefas, L. Comeau, N. Erdle, E. Montgomery, S. Amos and B. Purow: Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells. Neuro Oncol, 12(11), 1102-12 (2010)
    • (2010) Neuro Oncol , vol.12 , Issue.11 , pp. 1102-1112
    • Kefas, B.1    Comeau, L.2    Erdle, N.3    Montgomery, E.4    Amos, S.5    Purow, B.6
  • 68
    • 36448992338 scopus 로고    scopus 로고
    • Roles of HMGA proteins in cancer
    • DOI 10.1038/nrc2271, PII NRC2271
    • A. Fusco and M. Fedele: Roles of HMGA proteins in cancer. Nat Rev Cancer, 7(12), 899-910 (2007) (Pubitemid 350165857)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.12 , pp. 899-910
    • Fusco, A.1    Fedele, M.2
  • 73
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • DOI 10.1126/science.1137999
    • C. Mayr, M. T. Hemann and D. P. Bartel: Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science, 315(5818), 1576-9 (2007) (Pubitemid 46449474)
    • (2007) Science , vol.315 , Issue.5818 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 74
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • DOI 10.1016/j.cell.2007.10.054, PII S0092867407014171
    • F. Yu, H. Yao, P. Zhu, X. Zhang, Q. Pan, C. Gong, Y. Huang, X. Hu, F. Su, J. Lieberman and E. Song: let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell, 131(6), 1109-23 (2007) (Pubitemid 350235025)
    • (2007) Cell , vol.131 , Issue.6 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3    Zhang, X.4    Pan, Q.5    Gong, C.6    Huang, Y.7    Hu, X.8    Su, F.9    Lieberman, J.10    Song, E.11
  • 75
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • A. Sparmann and M. van Lohuizen: Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer, 6(11), 846-56 (2006) (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 76
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • S. Liu, G. Dontu, I. D. Mantle, S. Patel, N. S. Ahn, K. W. Jackson, P. Suri and M. S. Wicha: Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res, 66(12), 6063-71 (2006)
    • (2006) Cancer Res , vol.66 , Issue.12 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5    Jackson, K.W.6    Suri, P.7    Wicha, M.S.8
  • 78
    • 77955294582 scopus 로고    scopus 로고
    • MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence
    • S. Venkataraman, I. Alimova, R. Fan, P. Harris, N. Foreman and R. Vibhakar: MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence. PLoS One, 5(6), e10748 (2010)
    • (2010) PLoS One , vol.5 , Issue.6
    • Venkataraman, S.1    Alimova, I.2    Fan, R.3    Harris, P.4    Foreman, N.5    Vibhakar, R.6
  • 79
    • 78549288558 scopus 로고    scopus 로고
    • MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of the CDK2 and CDK4/6 cell cycle pathways
    • S. L. Lin, D. C. Chang, S. Y. Ying, D. Leu and D. T. Wu: MicroRNA miR-302 Inhibits the Tumorigenecity of Human Pluripotent Stem Cells by Coordinate Suppression of the CDK2 and CDK4/6 Cell Cycle Pathways. Cancer Res, 70(22), 9473-82 (2010)
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9473-9482
    • Lin, S.L.1    Chang, D.C.2    Ying, S.Y.3    Leu, D.4    Wu, D.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.