The relationship between obesity and prostate cancer: From genetics to disease treatment and prevention

BMC Medicine

Volumn 10, Issue , 2012, Pages

  Lughezzani, Giovanni ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

adipose tissue; gene expression; obesity; Prostate cancer

Indexed keywords

ADIPOSE TISSUE; CANCER GROWTH; CANCER PATIENT; CELL PROLIFERATION; DISEASE ASSOCIATION; GENE EXPRESSION; HEREDITY; HUMAN; IMMUNE RESPONSE; LEAN BODY WEIGHT; NOTE; OBESITY; PROGNOSIS; PROSTATE CANCER; TUMOR MICROENVIRONMENT;

ADIPOSE TISSUE; HUMANS; MALE; OBESITY; PROSTATIC NEOPLASMS; TRANSCRIPTOME;

EID: 84866558089     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-10-109     Document Type: Note

References (11)

1. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003, 348:1625-1638. 10.1056/NEJMoa021423, 12711737.
2. Amling CL, Riffenburgh RH, Sun L, Moul JW, Lance RS, Kusuda L, Sexton WJ, Soderdahl DW, Donahue TF, Foley JP, Chung AK, McLeod DG. Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomy. J Clin Oncol 2004, 22:439-445.
3. MacInnis RJ, English DR. Body size and composition and prostate cancer risk: systematic review and meta-regression analysis. Cancer Causes Control 2006, 17:989-1003. 10.1007/s10552-006-0049-z, 16933050.
4. Capitanio U, Suardi N, Briganti A, Gallina A, Abdollah F, Lughezzani G, Salonia A, Freschi M, Montorsi F. Influence of obesity on tumour volume in patients with prostate cancer. BJU Int 2012, 109:678-684. 10.1111/j.1464-410X.2011.10453.x, 21777363.
5. Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell 2011, 147:275-292. 10.1016/j.cell.2011.09.024, 22000009.
6. Cheng L, Darson MF, Bergstralh EJ, Slezak J, Myers RP, Bostwick DG. Correlation of margin status and extraprostatic extension with progression of prostate carcinoma. Cancer 1999, 86:1775-1782. 10.1002/(SICI)1097-0142(19991101)86:9<1775::AID-CNCR20>3.0.CO;2-L, 10547551.
7. Finley DS, Calvert VS, Inokuchi J, Lau A, Narula N, Petricoin EF, Zaldivar F, Santos R, Tyson DR, Ornstein DK. Periprostatic adipose tissue as a modulator of prostate cancer aggressiveness. J Urol 2009, 182:1621-1627. 10.1016/j.juro.2009.06.015, 19683746.
8. Ribeiro R, Monteiro C, Cunha V, Oliveira MJ, Freitas M, Fraga A, Príncipe P, Lobato C, Lobo F, Morais A, Silva V, Sanches-Magalhães J, Oliveira J, Pina F, Mota-Pinto A, Lopes C, Medeiros R. Human periprostatic adipose tissue promotes prostate cancer aggressiveness in vitro. J Exp Clin Cancer Res 2012, 31:32. 10.1186/1756-9966-31-32, 3379940, 22469146.
9. Sacca PA, Creydt VP, Choi H, Mazza ON, Fletcher SJ, Vallone VB, Scorticati C, Chasseing NA, Calvo JC. Human periprostatic adipose tissue: its influence on prostate cancer cells. Cell Physiol Biochem 2012, 30:113-122. 10.1159/000339051, 22759960.
10. Ribeiro R, Monteiro C, Catalán V, Hu P, Cunha V, Rodríguez A, Gómez-Ambrosi J, Fraga A, Príncipe P, Lobato C, Lobo F, Morais A, Silva V, Sanches-Magalhães J, Oliveira J, Pina F, Lopes C, Medeiros R, Fruhbeck G. Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue. BMC Med 2012, 10:108.
11. van Roermund JG, Hinnen KA, Tolman CJ, Bol GH, Witjes JA, Bosch JL, Kiemeney LA, van Vulpen M. Periprostatic fat correlates with tumour aggressiveness in prostate cancer patients. BJU Int 2011, 107:1775-1779. 10.1111/j.1464-410X.2010.09811.x, 21050356.