Ventilator-induced diaphragmatic vascular dysfunction

Critical Care Medicine

Volumn 40, Issue 10, 2012, Pages 2914-2915

  Zhu, Ercheng ^a   Sassoon, Catherine S H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

diaphragm muscle; electrical stimulation; hypoxia; mechanical ventilation; microvascular perfusion; oxidative stress

Indexed keywords

REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTIFICIAL VENTILATION; BLOOD FLOW; BRAIN DEATH; BREATHING; CLINICAL OBSERVATION; CONTROLLED MECHANICAL VENTILATION; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; DIAPHRAGM; DIAPHRAGM DISEASE; DIAPHRAGM MUSCLE; EDITORIAL; ELECTROSTIMULATION; HUMAN; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MUSCLE CELL; ORGAN DONOR; OXYGEN SUPPLY; OXYGEN TENSION; OXYGEN TRANSPORT; PHRENIC NERVE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; VASODILATATION; VENTILATOR; VENTILATOR INDUCED DIAPHRAGMATIC VASCULAR DYSFUNCTION;

ANIMALS; DIAPHRAGM; FEMALE; MICROCIRCULATION; RESPIRATION, ARTIFICIAL;

EID: 84866555032     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318263236e     Document Type: Editorial

References (17)

1. Vassilakopoulos T, Petrof BJ: Ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 2004; 169:336-341 (Pubitemid 38134811)
2. Powers SK, Shanely RA, Coombes JS, et al: Mechanical ventilation results in progressive contractile dysfunction in the diaphragm. J Appl Physiol 2002; 92:1851-1858 (Pubitemid 34666410)
3. Sassoon CS, Caiozzo VJ, Manka A, et al: Altered diaphragm contractile properties with controlled mechanical ventilation. J Appl Physiol 2002; 92:2585-2595 (Pubitemid 34666388)
4. Jung B, Constantin JM, Rossel N, et al: Adaptive support ventilation prevents ventilator-induced diaphragmatic dysfunction in piglet: An in vivo and in vitro study. Anesthesiology 2010; 112:1435-1443
5. Powers SK, Hudson MB, Nelson WB, et al: Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness. Crit Care Med 2011; 39:1749-1759
6. Hussain SN, Mofarrahi M, Sigala I, et al: Mechanical ventilation-induced diaphragm disuse in humans triggers autophagy. Am J Respir Crit Care Med 2010; 182:1377-1386
7. Smuder AJ, Hudson MB, Nelson WB, et al: Nuclear factor-κB signaling contributes to mechanical ventilation-induced diaphragm weakness. Crit Care Med 2012; 40:927-934
8. Davis RT III, Bruells CS, Stabley JN, et al: Mechanical ventilation reduces rat diaphragm blood fow and impairs oxygen delivery and uptake. Crit Care Med 2012; 40:2858-2866
9. Brancatisano A, Amis TC, Tully A, et al: Regional distribution of blood fow within the diaphragm. J Appl Physiol 1991; 71:583-589
10. Bellemare F, Wight D, Lavigne CM, et al: Effect of tension and timing of contraction on the blood fow of the diaphragm. J Appl Physiol 1983; 54:1597-1606 (Pubitemid 13059997)
11. McClung JM, Kavazis AN, Whidden MA, et al: Antioxidant administration attenuates mechanical ventilation-induced rat diaphragm muscle atrophy independent of protein kinase B (PKB Akt) signalling. J Physiol (Lond) 2007; 585(Pt 1):203-215 (Pubitemid 350131113)
12. Agten A, Maes K, Smuder A, et al: N-Acetyl-cysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation. Crit Care Med 2011; 39:777-782
13. Nathens AB, Neff MJ, Jurkovich GJ, et al: Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 2002; 236:814-822 (Pubitemid 35403237)
14. Sassoon CS, Zhu E, Caiozzo VJ: Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 2004; 170:626-632 (Pubitemid 39202204)
15. Sassoon CSH, Caiozzo VJ: Bench-to-bedside review: Diaphragm muscle function in disuse and acute high-dose corticosteroid treatment. Crit Care 2009; 13:221
16. Gayan-Ramirez G, Testelmans D, Maes K, et al: Intermittent spontaneous breathing protects the rat diaphragm from mechanical ventilation effects. Crit Care Med 2005; 33:2804-2809 (Pubitemid 41816415)
17. Ayas NT, McCool FD, Gore R, et al: Prevention of human diaphragm atrophy with short periods of electrical stimulation. Am J Respir Crit Care Med 1999; 159:2018-2020 (Pubitemid 29275079)