-
1
-
-
66249091930
-
The HER-2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine
-
Ross JS, Slodkowska EA, Symmans WF, Pusztai L, Ravdin PM, Hortobagyi GN (2009) The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist 14:68-320
-
(2009)
Oncologist
, vol.14
, pp. 68-320
-
-
Ross, J.S.1
Slodkowska, E.A.2
Symmans, W.F.3
Pusztai, L.4
Ravdin, P.M.5
Hortobagyi, G.N.6
-
2
-
-
73949090721
-
Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: An institutional-based review
-
Dawood S, Broglio K, Buzdar AU, Hortobagyi GN, Giordano SH (2010) Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review. J Clin Oncol 28:8-92
-
(2010)
J Clin Oncol
, vol.28
, pp. 8-92
-
-
Dawood, S.1
Broglio, K.2
Buzdar, A.U.3
Hortobagyi, G.N.4
Giordano, S.H.5
-
3
-
-
82955187799
-
Trastuzumab combined to neoadjuvant chemotherapy in patients with HER2-positive breast cancer: A systematic review and meta-analysis
-
Valachis A, Mauri D, Polyzos NP, Chlouverakis G, Mavroudis D, Georgoulias V (2011) Trastuzumab combined to neoadjuvant chemotherapy in patients with HER2-positive breast cancer: a systematic review and meta-analysis. Breast 20:485-490
-
(2011)
Breast
, vol.20
, pp. 485-490
-
-
Valachis, A.1
Mauri, D.2
Polyzos, N.P.3
Chlouverakis, G.4
Mavroudis, D.5
Georgoulias, V.6
-
4
-
-
34548444589
-
Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: A meta-analysis of published randomized trials
-
Viani GA, Afonso SL, Stefano EJ, De Fendi LI, Soares FV (2007) Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials. BMC Cancer 7:153
-
(2007)
BMC Cancer
, vol.7
, pp. 153
-
-
Viani, G.A.1
Afonso, S.L.2
Stefano, E.J.3
De Fendi, L.I.4
Soares, F.V.5
-
5
-
-
79957864200
-
The efficacy of HER2-targeted agents in metastatic breast cancer: A meta-analysis
-
Harris CA, Ward RL, Dobbins TA, Drew AK, Pearson S (2011) The efficacy of HER2-targeted agents in metastatic breast cancer: a meta-analysis. Ann Oncol 22:1308-1317
-
(2011)
Ann Oncol
, vol.22
, pp. 1308-1317
-
-
Harris, C.A.1
Ward, R.L.2
Dobbins, T.A.3
Drew, A.K.4
Pearson, S.5
-
6
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
DOI 10.1056/NEJMoa064320
-
Geyer CE, Forster J, Lindquist D et al (2006) Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 355:2733-2743 (Pubitemid 46021510)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.26
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
Chan, S.4
Romieu, C.G.5
Pienkowski, T.6
Jagiello-Gruszfeld, A.7
Crown, J.8
Chan, A.9
Kaufman, B.10
Skarlos, D.11
Campone, M.12
Davidson, N.13
Berger, M.14
Oliva, C.15
Rubin, S.D.16
Stein, S.17
Cameron, D.18
-
7
-
-
84877008887
-
Role of HER2 in wound-induced breast carcinoma proliferation
-
Tagliabue E, Agresti R, Carcangiu ML et al (2003) Role of HER2 in wound-induced breast carcinoma proliferation. Lancet 62: 33-527
-
(2003)
Lancet
, vol.62
, pp. 33-527
-
-
Tagliabue, E.1
Agresti, R.2
Carcangiu, M.L.3
-
8
-
-
32944461545
-
Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1182
-
Konecny GE, Pegram MD, Venkatesan N et al (2006) Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells. Cancer Res 66:1630-1639 (Pubitemid 43259947)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1630-1639
-
-
Konecny, G.E.1
Pegram, M.D.2
Venkatesan, N.3
Finn, R.4
Yang, G.5
Rahmeh, M.6
Untch, M.7
Rusnak, D.W.8
Spehar, G.9
Mullin, R.J.10
Keith, B.R.11
Gilmer, T.M.12
Berger, M.13
Podratz, K.C.14
Slamon, D.J.15
-
9
-
-
13744257860
-
Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis
-
DOI 10.1093/jnci/dji021
-
Mauri D, Pavlidis N, Ioannidis JP (2005) Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis. J Natl Cancer Inst 97:188-194 (Pubitemid 40277368)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.3
, pp. 188-194
-
-
Mauri, D.1
Pavlidis, N.2
Ioannidis, J.P.A.3
-
10
-
-
39149103122
-
Locally advanced and inflammatory breast cancer
-
DOI 10.1200/JCO.2008.15.0243
-
Chia S, Swain SM, Byrd DR, Mankoff DA (2008) Locally advanced and inflammatory breast cancer. J Clin Oncol 26:786-790 (Pubitemid 351264392)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.5
, pp. 786-790
-
-
Chia, S.1
Swain, S.M.2
Byrd, D.R.3
Mankoff, D.A.4
-
11
-
-
0031926839
-
Effect of preoperative chemotherapy on the outcome of women with operable breast cancer
-
Fisher B, Bryant J, Wolmark N et al (1998) Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 16:2672-2685 (Pubitemid 28363030)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.8
, pp. 2672-2685
-
-
Fisher, B.1
Bryant, J.2
Wolmark, N.3
Mamounas, E.4
Brown, A.5
Fisher, E.R.6
Wickerham, D.L.7
Begovic, M.8
DeCillis, A.9
Robidoux, A.10
Margolese, R.G.11
Cruz Jr., A.B.12
Hoehn, J.L.13
Lees, A.W.14
Dimitrov, N.V.15
Bear, H.D.16
-
12
-
-
79957601951
-
Pathologic complete response after neoadjuvant chemotherapy plus trastuzumab predicts favorable survival in human epidermal growth factor receptor 2-overexpressing breast cancer: Results from the TECHNO trial of the AGO and GBG study groups
-
Untch M, Fasching PA, Konecny GE et al (2011) Pathologic complete response after neoadjuvant chemotherapy plus trastuzumab predicts favorable survival in human epidermal growth factor receptor 2-overexpressing breast cancer: results from the TECHNO trial of the AGO and GBG study groups. J Clin Oncol 29:3351-3357
-
(2011)
J Clin Oncol
, vol.29
, pp. 3351-3357
-
-
Untch, M.1
Fasching, P.A.2
Konecny, G.E.3
-
13
-
-
84859001212
-
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
-
Cochrane Bias Methods Group
-
Higgins JP, Altman DG, Gøtzsche PC, Cochrane Bias Methods Group et al (2011) The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. Br Med J 343:d5928
-
(2011)
Br Med J
, vol.343
-
-
Higgins, J.P.1
Altman, D.G.2
Gøtzsche, P.C.3
-
14
-
-
84857236823
-
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): A randomised, open-label, multicentre, phase 3 trial
-
NeoALTTO Study Team
-
Baselga J, Bradbury I, Eidtmann H, NeoALTTO Study Team et al (2012) Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet 379:633-640
-
(2012)
Lancet
, vol.379
, pp. 633-640
-
-
Baselga, J.1
Bradbury, I.2
Eidtmann, H.3
-
15
-
-
84856444501
-
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): A randomised phase 3 trial
-
German Breast Group (GBG), Arbeitsgemeinschaft Gynäkologische Onkologie-Breast (AGOB) Study Group
-
Untch M, Loibl S, Bischoff J, German Breast Group (GBG), Arbeitsgemeinschaft Gynäkologische Onkologie-Breast (AGOB) Study Group et al (2012) Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial. Lancet Oncol 13:135-144
-
(2012)
Lancet Oncol
, vol.13
, pp. 135-144
-
-
Untch, M.1
Loibl, S.2
Bischoff, J.3
-
16
-
-
84864018421
-
Preoperative chemotherapy plus trastuzumab, lapatinib, or both in human epidermal growth factor receptor 2-positive operable breast cancer: Results of the randomized phase II CHER-LOB Study
-
Guarneri V, Frassoldati A, Bottini A et al (2012) Preoperative chemotherapy plus trastuzumab, lapatinib, or both in human epidermal growth factor receptor 2-positive operable breast cancer: results of the randomized phase II CHER-LOB Study. J Clin Oncol 30:1989-1995
-
(2012)
J Clin Oncol
, vol.30
, pp. 1989-1995
-
-
Guarneri, V.1
Frassoldati, A.2
Bottini, A.3
-
17
-
-
84866541367
-
Evaluation of lapatinib as a component of neoadjuvant therapy for HER2? operable breast cancer: NSABP protocol B-41
-
(suppl; abstr LBA506)
-
Robidoux A, Tang G, Rastogi P et al (2012) Evaluation of lapatinib as a component of neoadjuvant therapy for HER2? operable breast cancer: NSABP protocol B-41. J Clin Oncol (suppl; abstr LBA506)
-
(2012)
J Clin Oncol
-
-
Robidoux, A.1
Tang, G.2
Rastogi, P.3
-
18
-
-
80052895926
-
Correlation of molecular effects and pathologic complete response to preoperative lapatinib and trastuzumab, separately and combined prior to neoadjuvant breast cancer chemotherapy
-
(suppl; abstr 506)
-
Holmes FA, Nagarwala YM, Espina VA et al (2011) Correlation of molecular effects and pathologic complete response to preoperative lapatinib and trastuzumab, separately and combined prior to neoadjuvant breast cancer chemotherapy. J Clin Oncol (suppl; abstr 506)
-
(2011)
J Clin Oncol
-
-
Holmes, F.A.1
Nagarwala, Y.M.2
Espina, V.A.3
-
19
-
-
84877009675
-
Lapatinib vs trastuzumab in combination with standard EC-D chemotherapy in the neaodjuvant treatment of HER2? patients. Results from the GEICAM 2006-14 phase II randomized trial
-
(Abstract nr PD07-04)
-
Alba E, Albanell J, de la Haba J et al (2011) Lapatinib vs trastuzumab in combination with standard EC-D chemotherapy in the neaodjuvant treatment of HER2? patients. Results from the GEICAM 2006-14 phase II randomized trial. Cancer Res 71(24 Suppl):559s-560s (Abstract nr PD07-04)
-
(2011)
Cancer Res
, vol.71
, Issue.24 SUPPL.
-
-
Alba, E.1
Albanell, J.2
De La Haba, J.3
-
20
-
-
82155187061
-
Different mechanisms for resistance to trastuzumab versus lapatinib in HER2-positive breast cancers-role of estrogen receptor and HER2 reactivation
-
Wang YC, Morrison G, Gillihan R et al (2011) Different mechanisms for resistance to trastuzumab versus lapatinib in HER2-positive breast cancers-role of estrogen receptor and HER2 reactivation. Breast Cancer Res 13:R121
-
(2011)
Breast Cancer Res
, vol.13
-
-
Wang, Y.C.1
Morrison, G.2
Gillihan, R.3
-
21
-
-
84864066561
-
Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: Final results from the EGF104900 study
-
Blackwell KL, Burstein HJ, Storniolo AM et al (2012) Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 study. J Clin Oncol 30:2585-2592
-
(2012)
J Clin Oncol
, vol.30
, pp. 2585-2592
-
-
Blackwell, K.L.1
Burstein, H.J.2
Storniolo, A.M.3
-
22
-
-
84855297353
-
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): A randomised multicentre, open-label, phase 2 trial
-
Gianni L, Pienkowski T, Im YH et al (2012) Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol 13:25-32
-
(2012)
Lancet Oncol
, vol.13
, pp. 25-32
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.H.3
-
23
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
Baselga J, Cortés J, Kim SB, CLEOPATRA Study Group et al (2012) Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 366:109-119
-
(2012)
N Engl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortés, J.2
Kim, S.B.3
Study Group, C.4
-
24
-
-
34548222618
-
Lapatinib-associated toxicity and practical management recommendations
-
DOI 10.1634/theoncologist.12-7-756
-
Moy B, Goss PE (2007) Lapatinib-associated toxicity and practical management recommendations. Oncologist 12:756-765 (Pubitemid 47328219)
-
(2007)
Oncologist
, vol.12
, Issue.7
, pp. 756-765
-
-
Moy, B.1
Goss, P.E.2
-
25
-
-
84877008241
-
-
Accessed 20 June 2012
-
http://www.gsk.com/media/pressreleases/2011/2011-pressrelease-614837.htm. Accessed 20 June 2012
-
-
-
-
26
-
-
84866536687
-
Open-label phase III randomized controlled trial comparing taxane-based chemotherapy (Tax) with lapatinib L) or trastuzumab (T) as first-line therapy for women with HER2? metastatic breast cancer: Interim analysis (IA) of NCIC CTG MA.31/GSK EGF 108919
-
abstr LBA671
-
Gelmon KA, Boyle F, Kaufman B et al (2012) Open-label phase III randomized controlled trial comparing taxane-based chemotherapy (Tax) with lapatinib (L) or trastuzumab (T) as first-line therapy for women with HER2? metastatic breast cancer: interim analysis (IA) of NCIC CTG MA.31/GSK EGF 108919. J Clin Oncol 30:(suppl, abstr LBA671)
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Gelmon, K.A.1
Boyle, F.2
Kaufman, B.3
-
27
-
-
0034638918
-
New approaches to antibody therapy
-
DOI 10.1038/sj.onc.1204000
-
Weiner LM, Adams GP (2000) New approaches to antibody therapy. Oncogene 19:6144-6151 (Pubitemid 32059465)
-
(2000)
Oncogene
, vol.19
, Issue.53
, pp. 6144-6151
-
-
Weiner, L.M.1
Adams, G.P.2
-
28
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S et al (2001) Acquired resistance to the antitumor effect of epidermal growth factor receptor blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res 61:5090-5101 (Pubitemid 32681540)
-
(2001)
Cancer Research
, vol.61
, Issue.13
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
Hicklin, D.4
Bohlen, P.5
Schlaeppi, J.M.6
Rak, J.7
Kerbel, R.S.8
|