Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: A prospective nested case-control study

Critical Care Medicine

Volumn 40, Issue 10, 2012, Pages 2813-2820

  Vlaar, Alexander P J ^a   Hofstra, Jorrit J ^a   Determann, Rogier M ^a   Veelo, Denise P ^a   Paulus, Frederique ^a   Levi, Marcel ^a   Zeerleder, Sacha ^a,b   Vroom, Margreeth B ^a   Schultz, Marcus J ^a   Juffermans, Nicole P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b SANQUIN RESEARCH   (Netherlands)

Author keywords

acute lung injury; cardiac surgery; coagulation; inflammation; neutrophil; transfusion; transfusion related acute lung injury

Indexed keywords

ALPHA 1 ANTITRYPSIN; ELASTASE; INTERLEUKIN 6; INTERLEUKIN 8; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBIN ANTITHROMBIN COMPLEX;

ADULT; AGED; BLOOD CLOTTING DISORDER; CARDIAC PATIENT; CARDIOPULMONARY BYPASS; CASE CONTROL STUDY; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; ELECTIVE SURGERY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LUNG LAVAGE; MALE; PNEUMONIA; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; REVIEW; SURGICAL PATIENT; TRANSFUSION RELATED ACUTE LUNG INJURY;

ACUTE LUNG INJURY; AGED; AGED, 80 AND OVER; ALPHA 1-ANTITRYPSIN; BLOOD COAGULATION; BRONCHOALVEOLAR LAVAGE FLUID; CARDIAC SURGICAL PROCEDURES; CASE-CONTROL STUDIES; ERYTHROCYTE TRANSFUSION; FEMALE; HUMANS; INTENSIVE CARE UNITS; INTERLEUKINS; LEUKOCYTE ELASTASE; MALE; MIDDLE AGED; PNEUMONIA; PROSPECTIVE STUDIES;

EID: 84866536555     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31825b8e20     Document Type: Review

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