Langerhans cell sarcoma with an aberrant cytoplasmic CD3 expression

Diagnostic Pathology

Volumn 7, Issue 1, 2012, Pages

  Xu, Zhaodong ^a   Padmore, Ruth ^a   Faught, Carolyn ^a   Duffet, Lisa ^a   Burns, Bruce F ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Aberrant expression; CD3; Langerhans cell histiocytosis (LCH); Langerhans cell sarcoma (LCS); Lineage plasticity; Transdifferentiation

Indexed keywords

CD3 ANTIGEN; TUMOR MARKER;

AGED; ARTICLE; BIOPSY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FATALITY; GENE REARRANGEMENT; GENETICS; HEMATOLOGIC DISEASE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IMMUNOPHENOTYPING; LANGERHANS CELL SARCOMA; MALE; PALLIATIVE THERAPY; PATHOLOGY; PREDICTIVE VALUE;

AGED, 80 AND OVER; ANTIGENS, CD3; BIOPSY; FATAL OUTCOME; GENE REARRANGEMENT, T-LYMPHOCYTE; HEMATOLOGIC NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LANGERHANS CELL SARCOMA; MALE; PALLIATIVE CARE; PREDICTIVE VALUE OF TESTS; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 84866528721     PISSN: None     EISSN: 17461596     Source Type: Journal    
DOI: 10.1186/1746-1596-7-128     Document Type: Article

References (35)

1. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW. WHO classification of tumors of haematopoietic and lymphoid tissues 2008, France: International Agency for Research on Cancer.
2. Chikwava K, Jaffe R. Langerin (CD207) staining in normal pediatric tissues, reactive lymph nodes, and childhood histiocytic disorders. Pediatr Dev Pathol 2004, 7:607-614. 10.1007/s10024-004-3027-z, 15630529.
3. Krenács L, Tiszalvicz L, Krenács T, Boumsell L. Immunohistochemical detection of CD1A antigen in formalin-fixed and paraffin-embedded tissue sections with monoclonal antibody 010. J Pathol 1993, 171:99-104. 10.1002/path.1711710206, 7506772.
4. Pileri SA, Gaidano G, Zinzani PL, Pileri SA, Grogan TM, Harris NL, Banks P, Campo E, Chan JK, Favera RD, Delsol G, De Wolf-Peeters C, Falini B, Gascoyne RD, Gaulard P, Gatter KC, Isaacson PG, Jaffe ES, Kluin P, Knowles DM, Mason DY, Mori S, Müller-Hermelink HK, Piris MA, Ralfkiaer E, Stein H, Su IJ, Warnke RA, Weiss LM. Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology 2002, 41:1-29.
5. Uchida K, Kobayashi S, Inukai T, Noriki S, Imamura Y, Nakajima H, Yayama T, Orwotho N, Baba H. Langerhans cell sarcoma emanating from the upper arm skin: successful treatment by MAID regimen. J Orthop Sci 2008, 13:89-93. 10.1007/s00776-007-1184-4, 18274862.
6. Forero-Torres A, Leonard JP, Younes A, Rosenblatt JD, Brice P, Bartlett NL, Bosly A, Pinter-Brown L, Kennedy D, Sievers EL, Gopal AK. A Phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma. Br J Haematol 2009, 146:171-179. 10.1111/j.1365-2141.2009.07740.x, 19466965.
7. Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity And Response Criteria Of The Eastern Cooperative Oncology Group. Am J Clin Oncol 1982, 5:649-655. 10.1097/00000421-198212000-00014, 7165009.
8. Dacic S, Trusky C, Bakker A, Finkelstein SD, Yousem SA. Genotypic analysis of pulmonary Langerhans cell histiocytosis. Hum Pathol 2003, 34:1345-1349. 10.1016/j.humpath.2003.07.014, 14691922.
9. Yousem SA, Colby TV, Chen YY, Chen WG, Weiss LM. Pulmonary Langerhans' cell histiocytosis: molecular analysis of clonality. Am J Surg Pathol 2001, 25:630-636. 10.1097/00000478-200105000-00010, 11342775.
10. Bramwell NH, Burns BF. Histiocytosis X of the thymus in association with myasthenia gravis. Am J Clin Pathol 1986, 86:224-227.
11. Burns BF, Colby TV, Dorfman RF. Langerhans' cell granulomatosis (histiocytosis X) associated with malignant lymphomas. Am J Surg Pathol 1983, 7:529-533. 10.1097/00000478-198309000-00003, 6605095.
12. Merad M, Ginhoux F, Collin M. Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol 2008, 8:935-947. 10.1038/nri2455, 19029989.
13. Geissmann F, Prost C, Monnet JP, Dy M, Brousse N, Hermine O. Transforming growth factor beta1, in the presence of granulocyte / macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells. J Exp Med 1998, 187:961-966. 10.1084/jem.187.6.961, 2212193, 9500798.
14. Hoshino N, Katayama N, Shibasaki T, Ohishi K, Nishioka J, Masuya M, Miyahara Y, Hayashida M, Shimomura D, Kato T, Nakatani K, Nishii K, Kuribayashi K, Nobori T, Shiku H. A novel role for Notch ligand Delta-1 as a regulator of human Langerhans cell development from blood monocytes. J Leukoc Biol 2005, 78:921-929. 10.1189/jlb.1204746, 16037408.
15. Egeler RM, van Halteren AG, Hogendoorn PC, Laman JD, Leenen PJ. Langerhans cell histiocytosis: fascinating dynamics of the dendritic cell-macrophage lineage. Immunol Rev 2010, 234:213-232. 10.1111/j.0105-2896.2009.00883.x, 20193021.
16. Rasaiyaah J, Yong K, Katz DR, Kellam P, Chain BM. Dendritic cells and myeloid leukaemias: plasticity and commitment in cell differentiation. Br J Haematol 2007, 138:281-290. 10.1111/j.1365-2141.2007.06622.x, 17614817.
17. Anjuère F, del Hoyo GM, Martín P, Ardavín C. Langerhans cells develop from a lymphoid-committed precursor. Blood 2000, 96:1633-1637.
18. Chen W, Wang J, Wang E, Lu Y, Lau SK, Weiss LM, Huang Q. Detection of clonal lymphoid receptor gene rearrangements in langerhans cell histiocytosis. Am J Surg Pathol 2010, 34:1049-1057. 10.1097/PAS.0b013e3181e5341a, 20551822.
19. Feldman AL, Berthold F, Arceci RJ, Abramowsky C, Shehata BM, Mann KP, Lauer SJ, Pritchard J, Raffeld M, Jaffe ES. Clonal relationship between precursor T-lymphoblastic leukaemia/lymphoma and Langerhans-cell histiocytosis. Lancet Oncol 2005, 6:435-437. 10.1016/S1470-2045(05)70211-4, 15925822.
20. Feldman AL, Arber DA, Pittaluga S, Martinez A, Burke JS, Raffeld M, Camos M, Warnke R, Jaffe ES. Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: evidence for transdifferentiation of the follicular lymphoma clone. Blood 2008, 111:5433-5439. 10.1182/blood-2007-11-124792, 2424145, 18272816.
21. Shao H, Xi L, Raffeld M, Feldman AL, Ketterling RP, Knudson R, Rodriguez-Canales J, Hanson J, Pittaluga S, Jaffe ES. Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a study of seven cases. Mod Pathol 2011, 24:1421-1432. 10.1038/modpathol.2011.102, 3175277, 21666687.
22. Ratei R, Hummel M, Anagnostopoulos I, Jähne D, Arnold R, Dörken B, Mathas S, Benter T, Dudeck O, Ludwig WD, Stein H. Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity. Haematologica 2010, 95:1461-1466. 10.3324/haematol.2009.021212, 2930945, 20421277.
23. Feldman AL. Langerhans cell sarcoma, clonally related to the original follicular lymphoma, so called " Transdifferentiation" of the follicular lymphoma clone. USCAP 2010 hematopathology specialty conference handout
24. Sun J, Medeiros LJ, Lin P, Lu G, Bueso-Ramos CE, You MJ. Plasmablastic lymphoma involving the penis: a previously unreported location of a case with aberrant CD3 expression. Pathology 2011, 43:54-57. 10.1097/PAT.0b013e328340bbba, 21240066.
25. Wang E, Stoecker M. Primary mediastinal (thymic) large B cell lymphoma with aberrant expression of CD3: a case report with review of the literature. Int J Hematol 2010, 91:509-515. 10.1007/s12185-010-0501-4, 20131102.
26. Wallentine JC, Perkins SL, Tripp SR, Bruggman RD, Bayerl MG. Diffuse large B-cell lymphoma with coexpression of CD3 in a pediatric patient: a case report, review of the literature, and tissue microarray study. J Pediatr Hematol Oncol 2009, 31:124-127. 10.1097/MPH.0b013e31818b354a, 19194198.
27. Tzankov A, Bourgau C, Kaiser A, Zimpfer A, Maurer R, Pileri SA, Went P, Dirnhofer S. Rare expression of T-cell markers in classical Hodgkin's lymphoma. Mod Pathol 2005, 18:1542-1549.
28. Li S, Borowitz MJ. CD79a + T-cell lymphoblastic lymphoma with coexisting Langerhans cell histiocytosis. Arch Pathol Lab Med 2001, 125:958-960.
29. Ko YH, Kim WS, Kim Y. Expression of CD56 antigen in Langerhans cell histiocytosis associated with T-lymphoblastic lymphoma in a same lymph node. Virchovs Archiv 2006, 448:90-94.
30. Kawase T, Hamazaki M, Ogura M, Kawase Y, Murayama T, Mori Y, Nagai H, Tateno M, Oyama T, Kamiya Y, Taji H, Kagami Y, Naoe T, Takahashi T, Morishima Y, Nakamura S. CD56/NCAM-positive Langerhans cell sarcoma: a clinicopathologic study of 4 cases. Int J Haematol. 2005, 81:323-329.
31. Balogh Z, Szemlaky Z, Szendroi M, Antal I, Pápai Z, Fónyad L, Papp G, Changchien YC, Sápi Z. Correlation between DNA ploidy, metaphase high-resolution comparative genomic hybridization results and clinical outcome of synovial sarcoma. Diagn Pathol 2011, 6:107-114. 10.1186/1746-1596-6-107, 3214833, 22053830.
32. Babarović E, Zamolo G, Mustać E, Strčić M. High grade angiosarcoma arising in fibroadenoma. Diagn Pathol 2011, 6:125-130. 10.1186/1746-1596-6-125, 3284406, 22185665.
33. Bösmüller H, Gruber C, Haitchi-Petnehazy S, Wagner D, Webersinke G, Hauptmann S. Primary angiosarcoma of the ovary with prominent fibrosis of the ovarian stroma. Case report of an 81-year old patient. Diagn Pathol 2011, 6:65-71. 10.1186/1746-1596-6-65, 3143917, 21752298.
34. Mertens F, Stromberg U, Mandahl N, Dal Cin P, de Wever I, Fletcher CD, Mitelman F, Rosai J, Rydholm A, Sciot R, Tallini G, van den Berghe H, Vanni R, Willen H. Prognostically important chromosomal aberrations in soft tissue sarcomas: a report of the Chromosomes and Morphology (CHAMP) study group. Cancer Res 2002, 62:3980-3984.
35. Dreinhofer KE, Baldetorp B, Akerman M, Ferno M, Rydholm A, Gustofson P. DNA ploidy in soft tissue sarcoma: comparison of flow and image cytometry with clinical follow-up in 93 patients. Cytometry 2002, 50:19-24. 10.1002/cyto.10034, 11857594.