Application of Doehlert uniform shell designs for selecting optimal amounts of internal standards in the analysis of prostaglandins and leukotrienes by liquid chromatography-tandem mass spectrometry

Journal of Chromatography A

Volumn 1260, Issue , 2012, Pages 102-110

  Araujo, Pedro ^a   Janagap, Steve ^a,b   Holen, Elisabeth ^a  

^a INSTITUTE OF MARINE RESEARCH   (Norway)

^b UNIVERSITY OF THE PHILIPPINES   (Philippines)

Author keywords

Cell culture; Doehlert uniform shell designs; Eicosanoids; Multiple internal standards; Response factor

Indexed keywords

ANALYTES; ANTI-INFLAMMATORIES; CALIBRATION CURVES; CELL CULTURE MEDIA; CONCENTRATION REGION; DOEHLERT; DOEHLERT DESIGN; EICOSANOIDS; INTERNAL STANDARDS; KIDNEY CELLS; LACK-OF-FIT; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; OPTIMAL LEVEL; RESPONSE FACTOR; SHELL DESIGN; SUBSTANTIAL REDUCTION;

CELL CULTURE; DEUTERIUM; EXPERIMENTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATHEMATICAL MODELS; OPTIMIZATION;

STANDARDS;

LEUKOTRIENE; LEUKOTRIENE B4; LEUKOTRIENE B4 D4; LEUKOTRIENE B4 DERIVATIVE; LEUKOTRIENE B5; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN E2 D4; PROSTAGLANDIN E2 DERIVATIVE; PROSTAGLANDIN E3; UNCLASSIFIED DRUG;

ANALYTICAL ERROR; ANIMAL CELL; ARTICLE; CALIBRATION; CELL STIMULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; DOEHLERT UNIFORM SHELL DESIGN; EXPERIMENTAL DESIGN; FATTY ACID ANALYSIS; KIDNEY CELL; LIQUID CHROMATOGRAPHY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STANDARD; TANDEM MASS SPECTROMETRY; TIME; VALIDATION PROCESS;

ANIMALS; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; CULTURE MEDIA, CONDITIONED; GADIFORMES; LEUKOTRIENES; LINEAR MODELS; LIPOPOLYSACCHARIDES; PROSTAGLANDINS; REFERENCE STANDARDS; RESEARCH DESIGN; RNA, VIRAL; TANDEM MASS SPECTROMETRY;

EID: 84866526824     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.08.056     Document Type: Article

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