Aromatic-turmerone's anti-inflammatory effects in microglial cells are mediated by protein kinase A and heme oxygenase-1 signaling

Neurochemistry International

Volumn 61, Issue 5, 2012, Pages 767-777

  Park, Sun Young ^a   Kim, Young Hun ^a   Kim, Younghee ^a   Lee, Sang Joon ^a  

^a Pusan National University   (South Korea)

Author keywords

ar Turmerone; HO 1; MMP 9; Neuroinflammation; PKA; ROS

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENYLATE CYCLASE INHIBITOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIINFLAMMATORY AGENT; AROMATIC TURMERONE; CHEMOKINE; CURCUMA LONGA EXTRACT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYTOKINE; GELATINASE B; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NITRIC OXIDE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TURMERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME SYNTHESIS; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEME OXYGENASE-1; KETONES; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; MICROGLIA; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SESQUITERPENES; SIGNAL TRANSDUCTION;

EID: 84866523627     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.06.020     Document Type: Article

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