Efficacy of nonpharmacologic interventions for agitation in advanced dementia: A randomized, placebo-controlled trial

Journal of Clinical Psychiatry

Volumn 73, Issue 9, 2012, Pages 1255-1261

  Cohen Mansfield, Jiska ^a,b   Thein, Khin ^b   Marx, Marcia S ^b   Dakheel Ali, Maha ^b   Freedman, Laurence ^c  

^a TEL AVIV UNIVERSITY   (Israel)

^b Innovative Aging Research   (United States)

^c GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGITATION; ARTICLE; BEHAVIOR; BEHAVIOR DISORDER; CONTROLLED STUDY; DEMENTIA; FEMALE; HEALTH CARE NEED; HUMAN; MAJOR CLINICAL STUDY; MALE; NEEDS ASSESSMENT; PATIENT PREFERENCE; PLEASURE; PRIORITY JOURNAL; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; TREATMENT ROUTES FOR EXPLORING AGITATION;

EID: 84866519251     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.12m07918     Document Type: Article

References (31)

1. Cohen-Mansfield J, Billig N. Agitated behaviors in the elderly, 1: a conceptual review. J Am Geriatr Soc. 1986;34(10):711-721. PubMed
2. Cohen-Mansfield J, Werner P, Marx MS. An observational study of agitation in agitated nursing home residents. Int Psychogeriatr. 1989; 1(2):153-165. doi:10.1017/S10416102890165 PubMed
3. Rabinowitz J, Davidson M, De Deyn PP, et al. Factor analysis of the Cohen-Mansfield Agitation Inventory in three large samples of nursing home patients with dementia and behavioral disturbance. Am J Geriatr Psychiatry. 2005;13(11):991-998. PubMed
4. Jeste DV, Blazer D, Casey D, et al. ACNP White Paper: update on use of antipsychotic drugs in elderly persons with dementia. Neuropsychopharmacology. 2008;33(5):957-970. doi:10.1038/sj.np.1301492 PubMed
5. Pacher P, Kecskemeti V. Cardiovascular side effects of new antidepressants and antipsychotics: new drugs, old concerns? Curr Pharm Des. 2004;10(20):2463-2475. doi:10.2174/138161204383872 PubMed
6. Douzjian M, Wilson C, Shultz M, et al. A program to use pain control medication to reduce psychotropic drug use in residents with difficult behavior. Annals of Long-Term Care. 1998;6:174-179.
7. Cohen-Mansfield J, Werner P. Management of verbally disruptive behaviors in nursing home residents. J Gerontol A Biol Sci Med Sci. 1997;52(6):M369-M377. PubMed
8. Buettner L, Kolanowski A. Practice guidelines for recreation therapy in the care of people with dementia (CE). Geriatr Nurs (Minneap). 2003; 24(1):18-25. doi:10.1067/mgn.203.19
9. Cohen-Mansfield J. Theoretical frameworks for behavioral problems in dementia. Alzheimer's Care Quarterly. 2000;1(4):8-21.
10. Day K, Carreon D, Stump C. The therapeutic design of environments for people with dementia: a review of the empirical research. Gerontologist. 2000;40(4):397-416. PubMed
11. Fossey J, Ballard C, Juszczak E, et al. .Effect of enhanced psychosocial care on antipsychotic use in nursing home residents with severe dementia: cluster randomised trial. BMJ. 2006;332(7544):756-761. PubMed
12. Evans D, Wood J, Lambert L. A review of physical restraint minimization in the acute and residential care settings. J Adv Nurs. 2002;40(6): 616-625. doi:10.1046/j.1365-2648.202.0242.x PubMed
13. Gerdner LA, Swanson EA. Effects of individualized music on confused and agitated elderly patients. Arch Psychiatr Nurs. 1993;7(5):284-291. doi:10.1016/083-9417(93)906-I PubMed
14. Camberg L, Woods P, Ooi WL, et al. Evaluation of Simulated Presence: a personalized approach to enhance well-being in persons with Alzheimer's disease. J Am Geriatr Soc. 1999;47(4):446-452. PubMed
15. Lund DA, Hill RD, Caserta MS, et al. Video Respite: an innovative resource for family, professional caregivers, and persons with dementia. Gerontologist. 1995;35(5):683-687. PubMed
16. Sterritt PF, Pokorny ME. Art activities for patients with Alzheimer's and related disorders: working with art may help a client get back in touch with the outside world. Geriatr Nurs (Minneap). 1994;15(3):155-159. doi:10.1016/S0197-4572(09)9043-X
17. Kramer SC, Friedmann E, Bernstein PL. Comparison of the effect of human interaction, animal-assisted therapy, and AIBO-assisted therapy on long-term care residents with dementia. Anthrozoos: A Multidisciplinary Journal of The Interactions of People & Animals. 2009;22(1):43-57.
18. Cohen-Mansfield J. Non-pharmacological management of behavioral problems in persons with dementia: the TREA model. Alzheimer's Care Quarterly. 2000;1:22-34.
19. Cohen-Mansfield J, Libin A, Marx MS. Nonpharmacological treatment of agitation: a controlled trial of systematic individualized intervention. J Gerontol A Biol Sci Med Sci.2007;62(8):908-916. PubMed
20. Cohen-Mansfield J. Approaches to the management of disruptive behaviors. In: Rubinstein R, Lawton MP, eds. Alzheimer's Disease and Related Dementias: Strategies in Care and Research. New York, NY: Springer; 2000:39-65.
21. Morris J, Hawes C, Murphy K, et al. MDS Resident Assessment. Natick, MA: Eliot Press; 1991.
22. Morris JN, Fries BE, Morris SA. Scaling ADLs within the MDS. J Gerontol A Biol Sci Med Sci. 1999;54(11):M546-M553. PubMed
23. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198. doi:10.1016/02-3956(75)9026-6 PubMed
24. Lawton MP, Van Haitsma K, Klapper J. Observed affect in nursing home residents with Alzheimer's Disease. J Gerontol Psychol Sci Soc Sci. 1996; 51B(1):P3-P14. PubMed
25. Cohen-Mansfield J, Kerin P, Pawlson G, et al. Informed consent for research in a nursing home: processes and issues. Gerontologist. 1988.28(3):355-360. PubMed
26. Cohen-Mansfield J. Relatives' assessment of pain in cognitively impaired nursing home residents. J Pain Symptom Manage. 2002;24(6):562-571. doi:10.1016/S085-3924(02)0521-3 PubMed
27. Cohen-Mansfield J, Golander H, Arnheim G. Self-identity in older persons suffering from dementia: preliminary results. Soc Sci Med. 2000;51(3):381-394. doi:10.1016/S027-9536(9)0471-2 PubMed
28. Cohen-Mansfield J, Marx MS. The social network of the agitated nursing home resident. Research on Aging. 1992;14(1):110-123.
29. Cohen-Mansfield J, Werner P, Culpepper WJ 2nd, et al. Evaluation of an inservice training program on dementia and wandering. J Gerontol Nurs. 1997;23(10):40-47. PubMed
30. Kelley K. Confidence intervals for standardized effect sizes: theory, application and implementation. J Stat Softw. 2007;20(8):1-24.
31. Cohen-Mansfield J, Parpura-Gill A. Practice style in the nursing home: dimensions for assessment and quality improvement. Int J Geriatr Psychiatry. 2008;23(4):376-386. doi:10.102/gps.18 PubMed