Development and characterization of pharmacokinetic parameters of fast-dissolving films containing levocetirizine

Scientia Pharmaceutica

Volumn 80, Issue 3, 2012, Pages 779-787

  Choudhary, Dhagla R ^a   Patel, Vishnu A ^b   Chhalotiya, Usmangani K ^a   Patel, Harsha V ^a   Kundawala, Aliasgar J ^a  

^a Indukaka Ipcowala College of Pharmacy   (India)

^b AR Patel and GH Patel Institute of Pharmacy   (India)

Author keywords

Drug content; Fast dissolving film; In vitro dissolution studies; Levocetirizine; Pharmacokinetics

Indexed keywords

LEVOCETIRIZINE; POLYSORBATE 80; PROPYLENE GLYCOL; PULLULAN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FAST DISSOLVING FILM; FILM COATING; IN VITRO STUDY; NONHUMAN; RAT;

EID: 84866503574     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.1205-15     Document Type: Article

References (24)

1. Slowson M, Slowson S. What to do when patients cannot swallow their medications. Pharm Times. 1985; 51: 90-96.
2. Liang AC, Chen LH. Fast dissolving intraoral drug delivery systems. Exp Opin Ther Patents. 2001; 11: 981-986. http://dx.doi.org/10.1517/13543776.11.6.981.
3. Borsadia S, O'Halloran D, Osborne JL. Quick dissolving films-A novel approach to drug delivery. Drug Deliv Technol. 2003; 3: 63-66.
4. Vondrak B, Barnhart S. Dissolvable films for flexible product format in drug delivery. Pharm Tech. 2008: Suppl: S20-S28.
5. Vollmer U, Galfetti P. Rapid film: Oral thin films as an innovative drug delivery system and dosage form. Drug Dev Report. 2006; 64-67.
6. Klancke J. Dissolution testing of orally disintegrating tablets. Dissolution Technol. 2003; 10: 6-8.
7. Kay AB. Overview of allergy and allergic diseases: with a view to the future. Br Med Bull. 2000; 56: 843-864. http://dx.doi.org/10.1258/0007142001903481.
8. Holgate ST. Asthma and allergy--disorders of civilization? QJM. 1998; 91: 171-184.http://dx.doi.org/10.1093/qjmed/91.3.171.
9. Rusznak C, Davies RJ. ABC of allergies. Diagnosing allergy. BMJ. 1998; 316: 686-689. http://dx.doi.org/10.1136/bmj.316.7132.686.
10. http://en.wikipedia.org (03/03/2012).
11. Mahesh A, Shastri N, Sadanadam M. Development of Taste Masked Fast Desintegrating Films of Lecocetirizine Dihydrochloride For Oral Use. Current Drug Deliv. 2010; 7: 21-27. http://dx.doi.org/10.2174/156720110790396454.
12. Dinge A, Nagarsenker M. Formulation and evaluation of fast dissolving films for delivery of Triclosan to the oral cavity. AAPS PharmSciTech. 2008; 9: 349-356. http://dx.doi.org/10.1208/s12249-008-9047-7.
13. Rekha MR, Chandra PS. Pullulan as a promising biomaterial for biomedical applications: A perspective. Trends Biomater Artif Organs. 2007; 20: 1-6.
14. Diab T, Biliaderis CG, Gerasopoulos D, Sfakiotakis E. Physicochemical properties and application of pullulan edible films and coatings in fruit preservation. J Sci Food Agric. 2001; 81: 988-1000. http://dx.doi.org/10.1002/jsfa.883.
15. Mishra R, Amin A. Formulation and characterization of rapidly dissolving films of cetirizine hydrochloride using pullulan as a film forming agent. Indian J Pharm Educ Res. 2011; 45: 71-77.
16. Brindle LP, Krochta JM. Physical properties of whey protein-hydroxyl propyl methyl cellulose blend edible films. J Food Sci. 2008; 73: 446-454. http://dx.doi.org/10.1208/s12249-008-9047-7.
17. Felton LA, O'Donnell PB, McGinity JW. Mechanical properties of polymeric films prepared from aqueous dispersions. In: Aqueous polymeric coatings for pharmaceutical dosage forms. New York, USA: Informa health. 2008; 176-178.
18. Doaa AE, Nevine SA. Formulation of a novel tianeptine sodium orodispersible film. AAPS PharmSciTech. 2010; 11: 1018-1024. http://dx.doi.org/10.1208/s12249-010-9464-2.
19. Mashru RC, Sutariya VB, Sankalia MG, Parikh PP. Development and evaluation of fast dissolving film of salbutamol sulphate. Drug Dev Ind Pharm. 2005; 1: 25-34. http://www.ncbi.nlm.nih.gov/pubmed/15704855.
20. Gupta A, Gillard M, Christophe B, Chatelain P, Massingham R, Hammarlund-Udenaes M. Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig. Br J Pharmacol. 2007; 151: 1129-1136. http://dx.doi.org/10.1038/sj.bjp.0707318.
21. Shimoda H, Taniguchi K, Nishimura M, Matsuura K, Tsukioka T, Yamashita H. Preparation of a fast dissolving oral thin film containing dexamethasone: A possible application to antiemesis during cancer chemotherapy. Eur J Pharm Biopharm. 2009; 73: 361-365. http://dx.doi.org/10.1016/j.ejpb.2009.08.010.
22. Dedania Z, Dedania R, Karkhanis V, Sagar GV, Baldania M, Sheth NR. RP-HPLC Method for Simultaneous Estimation of Omeprazole and Ondansetron in combined dosage forms. Asian J Res Chem. 2009; 2: 108-111.
23. Arayne, AS, Sultana N, Nawaz M. Simultaneous quantification of cefpirome and cetirizine or levocetirizine in pharmaceutical formulations and human plasma by RP-HPLC. J Anal Chem. 2008; 63: 881-887. http://dx.doi.org/10.1134/S1061934808090153.
24. Macek J, Ptacek P, Kliima J. Determination of cetirizine in human plasma by high-performance liquid chromatography. J Chromatogr B. 1999; 736: 231-235. http://dx.doi.org/10.1016/S0378-4347(99)00464-8.