Excessive proinflammatory cytokine and chemokine responses of human monocyte-derived macrophages to enterovirus 71 infection

BMC Infectious Diseases

Volumn 12, Issue , 2012, Pages

  Gong, Xun ^a,b   Zhou, Jianfang ^b   Zhu, Wenfei ^b   Liu, Na ^b   Li, Jinsong ^b   Li, Lili ^b   Jin, Yu ^a,c   Duan, Zhaojun ^b  

^a LANZHOU UNIVERSITY   (China)

^b NATIONAL INSTITUTE FOR VIRAL DISEASE CONTROL AND PREVENTION   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Chemokines; Enterovirus 71; Macrophages; Proinflammatory cytokines; Toll like receptors

Indexed keywords

ALPHA INTERFERON; CHEMOKINE; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1; INTERLEUKIN 24; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; MACROPHAGE; MONOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROGENY; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS CELL INTERACTION; VIRUS INFECTIVITY; VIRUS RELEASE; VIRUS REPLICATION;

ADULT; CELLS, CULTURED; CYTOKINES; DEAD-BOX RNA HELICASES; ENTEROVIRUS A, HUMAN; GENE EXPRESSION PROFILING; HUMANS; MACROPHAGES; REAL-TIME POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTORS; YOUNG ADULT;

EID: 84866494514     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-12-224     Document Type: Article

References (34)

1. Weng KF, Chen LL, Huang PN, Shih SR. Neural pathogenesis of enterovirus 71 infection. Microbes Infect 2010, 12(7):505-510. 10.1016/j.micinf.2010.03.006, 20348010.
2. Lum LC, Wong KT, Lam SK, Chua KB, Goh AY, Lim WL, Ong BB, Paul G, AbuBakar S, Lambert M. Fatal enterovirus 71 encephalomyelitis. J Pediatr 1998, 133(6):795-798. 10.1016/S0022-3476(98)70155-6, 9842048.
3. Ho M, Chen ER, Hsu KH, Twu SJ, Chen KT, Tsai SF, Wang JR, Shih SR. An epidemic of enterovirus 71 infection in Taiwan. Taiwan Enterovirus Epidemic Working Group. N Engl J Med 1999, 341(13):929-935. 10.1056/NEJM199909233411301, 10498487.
4. Kim KH. Enterovirus 71 infection: an experience in Korea, 2009. Korean J Pediatr 2010, 53(5):616-622. 10.3345/kjp.2010.53.5.616, 2994121, 21189926.
5. Yang F, Ren L, Xiong Z, Li J, Xiao Y, Zhao R, He Y, Bu G, Zhou S, Wang J, et al. Enterovirus 71 outbreak in the People's Republic of China in 2008. J Clin Microbiol 2009, 47(7):2351-2352. 10.1128/JCM.00563-09, 2708525, 19439545.
6. Singh S, Chow VT, Phoon MC, Chan KP, Poh CL. Direct detection of enterovirus 71 (EV71) in clinical specimens from a hand, foot, and mouth disease outbreak in Singapore by reverse transcription-PCR with universal enterovirus and EV71-specific primers. J Clin Microbiol 2002, 40(8):2823-2827. 10.1128/JCM.40.8.2823-2827.2002, 120643, 12149336.
7. Shimizu H, Utama A, Yoshii K, Yoshida H, Yoneyama T, Sinniah M, Yusof MA, Okuno Y, Okabe N, Shih SR, et al. Enterovirus 71 from fatal and nonfatal cases of hand, foot and mouth disease epidemics in Malaysia, Japan and Taiwan in 1997-1998. Jpn J Infect Dis 1999, 52(1):12-15.
8. Shih SR, Ho MS, Lin KH, Wu SL, Chen YT, Wu CN, Lin TY, Chang LY, Tsao KC, Ning HC, et al. Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwan, 1998. Virus Res 2000, 68(2):127-136. 10.1016/S0168-1702(00)00162-3, 10958984.
9. Lin TY, Hsia SH, Huang YC, Wu CT, Chang LY. Proinflammatory cytokine reactions in enterovirus 71 infections of the central nervous system. Clin Infect Dis 2003, 36(3):269-274. 10.1086/345905, 12539066.
10. Wang SM, Lei HY, Su LY, Wu JM, Yu CK, Wang JR, Liu CC. Cerebrospinal fluid cytokines in enterovirus 71 brain stem encephalitis and echovirus meningitis infections of varying severity. Clin Microbiol Infect 2007, 13(7):677-682. 10.1111/j.1469-0691.2007.01729.x, 17441979.
11. Wang SM, Lei HY, Yu CK, Wang JR, Su IJ, Liu CC. Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis 2008, 198(7):1002-1006. 10.1086/591462, 18710325.
12. Williams K, Bar-Or A, Ulvestad E, Olivier A, Antel JP, Yong VW. Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J Neuropathol Exp Neurol 1992, 51(5):538-549. 10.1097/00005072-199209000-00009, 1517774.
13. Chen LC, Shyu HW, Chen SH, Lei HY, Yu CK, Yeh TM. Enterovirus 71 infection induces Fas ligand expression and apoptosis of Jurkat cells. J Med Virol 2006, 78(6):780-786. 10.1002/jmv.20623, 16628611.
14. Lin YW, Wang SW, Tung YY, Chen SH. Enterovirus 71 infection of human dendritic cells. Exp Biol Med (Maywood) 2009, 234(10):1166-1173.
15. Wang SM, Chen IC, Su LY, Huang KJ, Lei HY, Liu CC. Enterovirus 71 infection of monocytes with antibody-dependent enhancement. Clin Vaccine Immunol 2010, 17(10):1517-1523. 10.1128/CVI.00108-10, 2953001, 20685937.
16. Triantafilou K, Orthopoulos G, Vakakis E, Ahmed MA, Golenbock DT, Lepper PM, Triantafilou M. Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent. Cell Microbiol 2005, 7(8):1117-1126. 10.1111/j.1462-5822.2005.00537.x, 16008579.
17. Triantafilou K, Vakakis E, Orthopoulos G, Ahmed MA, Schumann C, Lepper PM, Triantafilou M. TLR8 and TLR7 are involved in the host's immune response to human parechovirus 1. Eur J Immunol 2005, 35(8):2416-2423. 10.1002/eji.200526149, 16025564.
18. Triantafilou K, Vakakis E, Richer EA, Evans GL, Villiers JP, Triantafilou M. Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response. Virulence 2011, 2(1):22-29. 10.4161/viru.2.1.13807, 3073236, 21224721.
19. Xu J, Yang Y, Wang C, Jiang B. Rotavirus and coxsackievirus infection activated different profiles of toll-like receptors and chemokines in intestinal epithelial cells. Inflamm Res 2009, 58(9):585-592. 10.1007/s00011-009-0022-x, 19296205.
20. Brown WF. Variance estimation in the reed-muench fifty per cent end-point determination. Am J Hyg 1964, 79:37-46.
21. Strizki JM, Albright AV, Sheng H, O'Connor M, Perrin L, Gonzalez-Scarano F. Infection of primary human microglia and monocyte-derived macrophages with human immunodeficiency virus type 1 isolates: evidence of differential tropism. J Virol 1996, 70(11):7654-7662. 190834, 8892885.
22. Wahid R, Cannon MJ, Chow M. Dendritic cells and macrophages are productively infected by poliovirus. J Virol 2005, 79(1):401-409. 10.1128/JVI.79.1.401-409.2005, 538697, 15596833.
23. Zhou J, Law HK, Cheung CY, Ng IH, Peiris JS, Lau YL. Differential expression of chemokines and their receptors in adult and neonatal macrophages infected with human or avian influenza viruses. J Infect Dis 2006, 194(1):61-70. 10.1086/504690, 16741883.
24. Lin TY, Chang LY, Huang YC, Hsu KH, Chiu CH, Yang KD. Different proinflammatory reactions in fatal and non-fatal enterovirus 71 infections: implications for early recognition and therapy. Acta Paediatr 2002, 91(6):632-635. 10.1111/j.1651-2227.2002.tb03292.x, 12162592.
25. Wang SM, Lei HY, Huang KJ, Wu JM, Wang JR, Yu CK, Su IJ, Liu CC. Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema. J Infect Dis 2003, 188(4):564-570. 10.1086/376998, 12898444.
26. Husseini RH, Sweet C, Collie MH, Smith H. Elevation of nasal viral levels by suppression of fever in ferrets infected with influenza viruses of differing virulence. J Infect Dis 1982, 145(4):520-524. 10.1093/infdis/145.4.520, 7069233.
27. Chen CS, Yao YC, Lin SC, Lee YP, Wang YF, Wang JR, Liu CC, Lei HY, Yu CK. Retrograde axonal transport: a major transmission route of enterovirus 71 in mice. J Virol 2007, 81(17):8996-9003. 10.1128/JVI.00236-07, 1951457, 17567704.
28. Fiala M, Looney DJ, Stins M, Way DD, Zhang L, Gan X, Chiappelli F, Schweitzer ES, Shapshak P, Weinand M, et al. TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier. Mol Med 1997, 3(8):553-564. 2230176, 9307983.
29. Kimura Y. Cytokines and chemokines induced by influenza virus infection. Nihon Rinsho 2006, 64(10):1822-1827.
30. Lei X, Liu X, Ma Y, Sun Z, Yang Y, Jin Q, He B, Wang J. The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses. J Virol 2010, 84(16):8051-8061. 10.1128/JVI.02491-09, 2916543, 20519382.
31. Ostergaard C, Benfield TL, Sellebjerg F, Kronborg G, Lohse N, Lundgren JD. Interleukin-8 in cerebrospinal fluid from patients with septic and aseptic meningitis. Eur J Clin Microbiol Infect Dis 1996, 15(2):166-169. 10.1007/BF01591492, 8801091.
32. Kawai T, Akira S. Innate immune recognition of viral infection. Nat Immunol 2006, 7(2):131-137.
33. Shalekoff S, Gray GE, Tiemessen CT. Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers. Clin Diagn Lab Immunol 2004, 11(1):229-234. 321339, 14715575.
34. Hamaguchi T, Fujisawa H, Sakai K, Okino S, Kurosaki N, Nishimura Y, Shimizu H, Yamada M. Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult. Emerg Infect Dis 2008, 14(5):828-830. 10.3201/eid1405.071121, 2600258, 18439374.