In vitro characterization of multivalent adhesion molecule 7-based inhibition of multidrug-resistant bacteria isolated from wounded military personnel

Virulence

Volumn 3, Issue 4, 2012, Pages 389-399

  Krachler, Anne Marie ^a   Mende, Katrin ^b,c   Murray, Clinton ^c   Orth, Kim ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c SAN ANTONIO MILITARY MEDICAL CENTER   (United States)

Author keywords

Acinetobacter; Adhesin; Anti adhesion treatment; Bacterial attachment; Klebsiella; MAM7; Multidrug resistance; Pseudomonas; Wound infections

Indexed keywords

ADHESIN; AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; CEFALOTIN; CEFAZOLIN; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CIPROFLOXACIN; COTRIMOXAZOLE; ERTAPENEM; GATIFLOXACIN; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; MULTIVALENT ADHESION MOLECULE 7; NITROFURANTOIN; PIPERACILLIN; SULTAMICILLIN; TAZOBACTAM; TETRACYCLINE; TOBRAMYCIN; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ACINETOBACTER CALCOACETICUS; ANTIBIOTIC SENSITIVITY; ARMY; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BACTERIUM ISOLATION; BATTLE INJURY; BIOFILM; CLINICAL ARTICLE; CYTOTOXICITY; DISEASE TRANSMISSION; ESCHERICHIA COLI; GENETIC VARIABILITY; HOSPITAL INFECTION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MULTIDRUG RESISTANCE; NONHUMAN; PSEUDOMONAS AERUGINOSA; WOUND INFECTION;

ACINETOBACTER; ACINETOBACTER BAUMANNII; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; KLEBSIELLA; KLEBSIELLA PNEUMONIAE; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 84866492320     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: 10.4161/viru.20816     Document Type: Article

References (39)

1. Hospenthal DR, Green AD, Crouch HK, English JF, Pool J, Yun HC, et al. Prevention of Combat-Related Infections Guidelines Panel. Infection prevention and control in deployed military medical treatment facilities. J Trauma 2011; 71(Suppl 2):S290-8. PMID:21814095; http://dx.doi.org/10.1097/TA.0b013e318227add8
2. Murray CK, Roop SA, Hospenthal DR, Dooley DP, Wenner K, Hammock J, et al. Bacteriology of war wounds at the time of injury. Mil Med 2006; 171:826-9. PMID:17036599
3. Yun HC, Murray CK, Roop SA, Hospenthal DR, Gourdine E, Dooley DP. Bacteria recovered from patients admitted to a deployed U.S. military hospital in Baghdad, Iraq. Mil Med 2006; 171:821-5. PMID: 17036598
4. O'Shea MK. Acinetobacter in modern warfare. Int J Antimicrob Agents 2012; 39:363-75. PMID:22459899; http://dx.doi.org/10.1016/j.ijantimicag.2012.01.018
5. Masini BD, Waterman SM, Wenke JC, Owens BD, Hsu JR, Ficke JR. Resource utilization and disability outcome assessment of combat casualties from Operation Iraqi Freedom and Operation Enduring Freedom. J Orthop Trauma 2009; 23:261-6. PMID:19318869; http://dx.doi.org/10.1097/BOT.0b013e31819dfa04
6. Calhoun JH, Murray CK, Manring MM. Multidrugresistant organisms in military wounds from Iraq and Afghanistan. Clin Orthop Relat Res 2008; 466: 1356-62. PMID:18347888; http://dx.doi.org/10.1007/s11999-008-0212-9
7. Antimicrobial Resistance. Issues and Options. In: Harrison PF, Lederberg J, eds. Forum on Emerging Infections. Washington, DC: National Academy Press, 1998:8-74.
8. Murray CK, Hospenthal DR, Kotwal RS, Butler FK. Efficacy of point-of-injury combat antimicrobials. J Trauma 2011; 71(Suppl 2):S307-13. PMID:21814097;http://dx.doi.org/10.1097/TA.0b013e318227af79
9. Krachler AM, Ham H, Orth K. Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gramnegative pathogens. Proc Natl Acad Sci U S A 2011; 108:11614-9. PMID:21709226; http://dx.doi.org/10.1073/pnas.1102360108
10. Krachler AM, Orth K. Functional characterization of the interaction between bacterial adhesin multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands. J Biol Chem 2011; 286:38939-47. PMID: 21937438; http://dx.doi.org/10.1074/jbc.M111.291377
11. Krachler AM, Ham H, Orth K. Turnabout is fair play: use of the bacterial Multivalent Adhesion Molecule 7 as an antimicrobial agent. Virulence 2012; 3:68-71. PMID:22086133; http://dx.doi.org/10.4161/viru.3.1.18172
12. Murray CK, Yun HC, Griffith ME, Thompson B, Crouch HK, Monson LS, et al. Recovery of multidrugresistant bacteria from combat personnel evacuated from Iraq and Afghanistan at a single military treatment facility. Mil Med 2009; 174:598-604. PMID:19585772
13. Tribble DR, Conger NG, Fraser S, Gleeson TD, Wilkins K, Antonille T, et al. Infection-associated clinical outcomes in hospitalized medical evacuees after traumatic injury: trauma infectious disease outcome study. J Trauma 2011; 71(Suppl):S33-42.PMID:21795875; http://dx.doi.org/10.1097/TA.0b013e318221162e
14. Firon N, Ashkenazi S, Mirelman D, Ofek I, Sharon N. Aromatic alpha-glycosides of mannose are powerful inhibitors of the adherence of type 1 fimbriated Escherichia coli to yeast and intestinal epithelial cells. Infect Immun 1987; 55:472-6. PMID:3542836
15. Joosten JA, Loimaranta V, Appeldoorn CC, Haataja S, El Maate FA, Liskamp RM, et al. Inhibition of Streptococcus suis adhesion by dendritic galabiose compounds at low nanomolar concentration. J Med Chem 2004; 47:6499-508. PMID:15588085; http://dx.doi.org/10.1021/jm049476+
16. Salminen A, Loimaranta V, Joosten JA, Khan AS, Hacker J, Pieters RJ, et al. Inhibition of P-fimbriated Escherichia coli adhesion by multivalent galabiose derivatives studied by a live-bacteria application of surface plasmon resonance. J Antimicrob Chemother 2007; 60:495-501. PMID:17623698; http://dx.doi.org/10.1093/jac/dkm251
17. Thomas RJ. Receptor mimicry as novel therapeutic treatment for biothreat agents. Bioeng Bugs 2010; 1:17-30. PMID:21327124; http://dx.doi.org/10.4161/bbug.1.1.10049
18. Hawley JS, Murray CK, Griffith ME, McElmeel ML, Fulcher LC, Hospenthal DR, et al. Susceptibility of acinetobacter strains isolated from deployed U.S. military personnel. Antimicrob Agents Chemother 2007; 51:376-8. PMID:17043112; http://dx.doi.org/10.1128/AAC.00858-06
19. Dallo SF, Weitao T. Insights into acinetobacter warwound infections, biofilms, and control. Adv SkinWound Care 2010; 23:169-74. PMID:20299843; http://dx.doi.org/10.1097/01.ASW.0000363527.08501.a3
20. Schierle CF, De la Garza M, Mustoe TA, Galiano RD. Staphylococcal biofilms impair wound healing by delaying reepithelialization in a murine cutaneous wound model. Wound Repair Regen 2009; 17:354-9. PMID:19660043; http://dx.doi.org/10.1111/j.1524-475X.2009.00489.x
21. Davis SC, Ricotti C, Cazzaniga A, Welsh E, Eaglstein WH, Mertz PM. Microscopic and physiologic evidence for biofilm-associated wound colonization in vivo. Wound Repair Regen 2008; 16:23-9. PMID:18211576; http://dx.doi.org/10.1111/j.1524-475X.2007.00303.x
22. Vance RE, Rietsch A, Mekalanos JJ. Role of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivo. Infect Immun 2005; 73:1706-13. PMID:15731071; http://dx.doi.org/10.1128/IAI.73.3.1706-1713.2005
23. Matsuda S, Kodama T, Okada N, Okayama K, Honda T, Iida T. Association of Vibrio parahaemolyticus thermostable direct hemolysin with lipid rafts is essential for cytotoxicity but not hemolytic activity. Infect Immun 2010; 78:603-10. PMID:19933828; http://dx.doi.org/10.1128/IAI.00946-09
24. Kim YR, Lee SE, Kook H, Yeom JA, Na HS, Kim SY, et al. Vibrio vulnificus RTX toxin kills host cells only after contact of the bacteria with host cells. Cell Microbiol 2008; 10:848-62. PMID:18005241; http://dx.doi.org/10.1111/j.1462-5822.2007.01088.x
25. Zrimi J, Ng Ling A, Giri-Rachman Arifin E, Feverati G, Lesieur C. Cholera toxin B subunits assemble into pentamers-proposition of a fly-casting mechanism. PLoS One 2010; 5:e15347. PMID:21203571; http://dx.doi.org/10.1371/journal.pone.0015347
26. Cambronne ED, Roy CR. Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems. Traffic 2006; 7:929-39. PMID:16734660; http://dx.doi.org/10.1111/j.1600-0854.2006.00446.x
27. Filloux A, Hachani A, Bleves S. The bacterial type VI secretion machine: yet another player for protein transport across membranes. Microbiology 2008;154:1570-83. PMID:18524912; http://dx.doi.org/10.1099/mic.0.2008/016840-0
28. Winnen B, Schlumberger MC, Sturm A, Schüpbach K, Siebenmann S, Jenny P, et al. Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system. PLoS One 2008; 3: e2178. PMID:18478101; http://dx.doi.org/10.1371/journal.pone.0002178
29. Bomberger JM, Maceachran DP, Coutermarsh BA, Ye S, O'Toole GA, Stanton BA. Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. PLoS Pathog 2009; 5: e1000382. PMID:19360133; http://dx.doi.org/10.1371/journal.ppat.1000382
30. Haurat MF, Aduse-Opoku J, Rangarajan M, Dorobantu L, Gray MR, Curtis MA, et al. Selective sorting of cargo proteins into bacterial membrane vesicles. J Biol Chem 2011; 286:1269-76. PMID:21056982; http://dx.doi.org/10.1074/jbc.M110.185744
31. Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, et al. Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Proteomics 2011; 11:3424-9. PMID:21751344; http://dx.doi.org/10.1002/pmic.201000212
32. Kulp A, Kuehn MJ. Biological functions and biogenesis of secreted bacterial outer membrane vesicles. Annu Rev Microbiol 2010; 64:163-84. PMID:20825345; http://dx.doi.org/10.1146/annurev.micro.091208.073413
33. Jin JS, Kwon SO, Moon DC, Gurung M, Lee JH, Kim SI, et al. Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. PLoS One 2011; 6:e17027. PMID:21386968; http://dx.doi.org/10.1371/journal.pone.0017027
34. Parker H, Chitcholtan K, Hampton MB, Keenan JI. Uptake of Helicobacter pylori outer membrane vesicles by gastric epithelial cells. Infect Immun 2010; 78:5054-61. PMID:20876296; http://dx.doi.org/10.1128/IAI.00299-10
35. Akers KS, Mende K, Yun HC, Hospenthal DR, Beckius ML, Yu X, et al. Tetracycline susceptibility testing and resistance genes in isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus complex from a U.S. military hospital. Antimicrob Agents Chemother 2009; 53:2693-5. PMID:19307365; http://dx.doi.org/10.1128/AAC.01405-08
36. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, et al. Interpreting chromosomal DNA restriction patterns produced by pulsedfield gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33:2233-9. PMID:7494007
37. El-Shazly S, Ahmad S, Mustafa AS, Al-Attiyah R, Krajci D. Internalization by HeLa cells of latex beads coated with mammalian cell entry (Mce) proteins encoded by the mce3 operon of Mycobacterium tuberculosis. J Med Microbiol 2007; 56:1145-51. PMID:17761475; http://dx.doi.org/10.1099/jmm.0.47095-0
38. Cockerill FR, Wikler MA, Alder J, Dudley MN, Eliopoulos GM, Ferraro MJ, et al. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Infromational Supplement. Clinical and Laboratory Standards Institute, 2012.
39. Percival SL, Hill KE, Malic S, Thomas DW, Williams DW. Antimicrobial tolerance and the significance of persister cells in recalcitrant chronic wound biofilms. Wound Repair Regen 2011; 19:1-9. PMID:21235682; http://dx.doi.org/10.1111/j.1524-475X.2010.00651.x