Surprise, surprise: Idiopathic, isolated complete atrioventricular block may be heritable

Circulation

Volumn 126, Issue 12, 2012, Pages 1434-1435

  Cannon, Bryan C ^a   Ackerman, Michael J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOMYOPATHY; COMPLETE HEART BLOCK; DISEASE ASSOCIATION; EDITORIAL; ELECTROCARDIOGRAPHY; GENE MUTATION; HEART CONDUCTION; HUMAN; PACEMAKER; PRIORITY JOURNAL; QRS COMPLEX; QT PROLONGATION; TREATMENT INDICATION;

ATRIOVENTRICULAR BLOCK; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MASS SCREENING; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PARENTS; PREGNANCY;

EID: 84866492031     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.130575     Document Type: Editorial

References (8)

1. Baruteau AE, Behaghel A, Fouchard S, Mabo P, Schott JJ, Dina C, Chatel S, Villain E, Thambo JB, Marçon F, Gournay V, Rouault F, Chantepie A, Guillaumont S, Godart F, Martins RP, Delasalle B, Bonnet C, Fraisse A, Schleich JM, Lusson JR, Dulac Y, Daubert JC, Le Marec H, Probst V. Parental electrocardiographic screening identifies a high degree of inheritance for congenital and childhood nonimmune isolated atrioventricular block. Circulation. 2012;126:1469-1477.
2. Michaelsson M, Engle M. Congenital complete heart block: an international study of the natural history. Cardiovasc Clin. 1972;4:85-101.
3. Scott JS, Maddison PJ, Taylor PV, Esscher E, Scott O, Skinner RP. Connective-tissue disease, antibodies to ribonucleoprotein, and congenital heart block. N Engl J Med. 1983;309:209-212. (Pubitemid 13070239)
4. Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, Pradervand S, Evans SM, Clark B, Feramisco JR, Giles W, Ho SY, Benson DW, Silberbach M, Shou W, Chien KR. Nkx2-5 pathways and congenital heart disease: loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell. 2004;117: 373-386. (Pubitemid 38534543)
5. Medeiros-Domingo A, Kaku T, Tester DJ, Iturralde-Torres P, Itty A, Ye B, Valdivia C, Ueda K, Canizales-Quinteros S, Tusié-Luna MT, Makielski JC, Ackerman MJ. SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome. Circulation. 2007;116:134-142. (Pubitemid 47057518)
6. Ackerman MJ. Cardiac channelopathies: it's in the genes. Nat Med. 2004;10:463-464. (Pubitemid 38667902)
7. Epstein AE, Dimarco JP, Ellenbogen KA, Estes NA 3rd, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO; American College of Cardiology; American Heart Association Task Force on Practice Guidelines; American Association for Thoracic Surgery; Society of Thoracic Surgeons. ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities. Heart Rhythm. 2008;5:e1-e62.
8. Ackerman MJ, Priori SG, Willems S, Berul C, Brugada R, Calkins H, Camm AJ, Ellinor PT, Gollob M Hamilton R, Hershberger RE, Judge DP, Le Marec H, McKenna WJ, Schulze-Bahr E, Semsarian C, Towbin JA, Watkins H, Wilde A, Wolpert C, Zipes DP. Heart Rhythm Society; European Heart Rhythm Association. HRS/EHRS expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association. Heart Rhythm. 2011;8:1308-1339.