Improvement of the prediction power of the CoMFA and CoMSIA models on histamine H3 antagonists by different variable selection methods

Scientia Pharmaceutica

Volumn 80, Issue 3, 2012, Pages 547-566

  Ghasemi, Jahan B ^a   Tavakoli, Hossein ^a  

^a K N TOOSI UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

Enhanced replacement method; Genetic algorithm; Histamine H3 antagonists; Stepwise multiple linear regression; Successive projection algorithm

Indexed keywords

HISTAMINE H3 RECEPTOR ANTAGONIST;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG ACTIVITY; DRUG STRUCTURE; GENETIC ALGORITHM; HYDROGEN BOND; IC 50; MULTIPLE LINEAR REGRESSION ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATIC ELECTRICITY;

EID: 84866486769     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.1204-19     Document Type: Article

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