Acute toxicity of chemoradiation for rectal cancer;Akuttoxizitat der simultanen radiochemotherapie des rektumkarzinoms

Strahlentherapie und Onkologie

Volumn 173, Issue 8, 1997, Pages 415-421

  Rodel G ^a,b   Fietkau, R ^a   Keilholz, L ^a   Grabenbauer, G G ^a   Kessler, H ^a   Martus, P ^a   Sauer, R ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

5 Fluorouracil; Acute toxicity; Rectal cancer; Simultaneous chemoradiation

Indexed keywords

FLUOROURACIL;

ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; DIARRHEA; HUMAN; LEUKOPENIA; MAJOR CLINICAL STUDY; POSTOPERATIVE CARE; PREOPERATIVE TREATMENT; RECTUM CANCER; RECTUM SURGERY; SKIN IRRITATION;

EID: 84866470213     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03038317     Document Type: Article

References (20)

1. Etienne, M. C., J. L. Lagrange, O. Dassonville, R. Fleming, A. Thyss, N. Renée, M. Schneider, F. Demard, G. Milano: Population study of dihydropyrimidine dehydrogenase in cancer patients. J. clin. Oncol. 12 (1994), 2248-2253.
2. Gallagher, M. J., H. D. Brereton, R. A. Rostock, J. M. Zero, D. A. Zekosky, L. F. Poyss, M. P. Richter, M. M. Kligerman: A prospective study of treatment techniques to minimize the volume of pelvic small bowel with reduction of acute and late effects associated with pelvic irradiation. Int. J. Radiat. Oncol. Biol. Phys. 12 (1986), 1565-1573.
3. Gastrointestinal Tumor Study Group: Survival after postoperative combination treatments of cancer. New Engl. J. Med. 315 (1986), 1294-1295.
4. Heggie, G. D., J. P. Sommadossi, D. S. Cross, W. J. Huster, R. B. Diasio: Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res. 47 (1987), 2203-2206.
5. Herbert, S. H., W. J. Curran, L. J. Solin, P. M. Stafford, R. M. Lanciano, G. H. Hanks: Decreasing gastrointestinal morbidity with the use of small bowel contrast during treatment planning for pelvic radiation. Int. J. Radiat. Oncol. Biol. Phys. 20 (1991), 835-842.
6. Hombrink, J., A.-C. Voss, D. Fröhlich, M. Gletzel, A. Krau, F. H. Glaser: Therapieansätze zur Prophylaxe der strahleninduzierten Diarrhoe nach Becken- und Abdominalbestrahlung. Strahlenther. Onkol. 171 (1995), 49-53.
7. Krook, J. E., C. G. Moertel, L. L. Gunderson, H. S. Wieand, R. T. Coffins, R. W. Beart, T. P. Kubista, M. A. Poon, W. C. Meyers, J. A. Mailliard, D. L. Twito, R. F. Morton, M. H. Veeder, T. E. Witzig, S. Cha, S. C. Vidyarth: Effective surgical adjuvant therapy for high-risk rectal carcinoma. New Engl. J. Med. 324 (1991), 709-715.
8. Letschert, J. G. J., J.V. Lebesque, B. M. P. Aleman, J. F. Bosset, J. C. Horiot, H. Bertelink, L. Cionini, J. P. Hamers, J. W. H. Leer, M. Van Glabbeke: The volume effect in radiation-related small bowel complications: results of a clinical study of the EORTC Radiotherapy Cooperative Group in patients treated for rectal carcinoma. Radiother. Oncol. 32 (1994), 116-123.
9. Milano, G., M. C. Etiene, E. Cassuto-Viguier, A. Thyss, J. Santini, M. Frenay, N. Renee, M. Schneider, F. Demard: Influence of sex and age on fluorouracil clearance. J. clin. Oncol. 10 (1992), 1171-1175.
10. Minsky, B. D., A. M. Cohen, N. Kemeny, W. E. Enker, D. P. Kelsen, B. Reichmann, L. Saltz, E. R. Sigurdson, J. Frankel: Combined modality therapy of rectal cancer: decreased acute toxicity with the preoperative approach. J. clin. Oncol. 10 (1992), 1218-1224.
11. Minsky, B. D., J. A. Conti, Y. Huang, K. Knopf: Relationship of acute gastrointestinal toxicity and the volume of irradiated small bowel in patients receiving combined modality therapy for rectal cancer. J. clin. Oncol. 13 (1995), 1409-1416.
12. NIH Consensus Conference: Adjuvant therapy for patients with colon and rectal cancer. J. Amer. Med. Ass. 264 (1990), 1444.
13. Philips, T. L.: Tissue toxicity of radiation-drug interactions. In: Sokol, G. H., R. P. Maickel (eds.): Radiation-drug interactions in the treatment of cancer. Wiley, New York 1980, p. 87-94.
14. Port, R. E., B. Daniel, R. W. Ding, R. Hermann: Relative importance of dose, body surface, sex and age for 5-fluorouracil clearance. Oncology 48 (1991), 277-281.
15. Rudat, V., M. Flentje, R. Engenhart, M. Metzger, M. Wannenmacher: Lochbrettechnik zur Dünndarmschonung. Strahlenther. Onkol. 171 (1995), 437-443.
16. Russ, J., G. Smoron, J. Gagnon: Omental transposition flap in colorectal carcinoma: adjunctive use in prevention and treatment of radiation complications. Int. J. Radiat. Oncol. Biol. Phys. 10 (1984), 55-62.
17. Santini, J., G. Milano, A. Thyss, N. Renee, P. Viens, P. Ayela, M. Schneider, F. Demard: 5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer. Brit. J. Cancer 59 (1989), 287-290.
18. Scott, H., L. Solin, J. Hoffmann, D. Schultz, W. Curran, R. Lanciano, N. Rosenblum, M. Hogan, B. Eisenberg, G. Hanks: Volumetric analysis of small bowel displacement for radiation portals with the use of pelvic tissue expander. Int. J. Radiat. Oncol. Biol. Phys. 25 (1993), 885-893.
19. Stein, B. N., N. J. Petrelli, H. O. Douglass, D. L. Driscoll, G. Arcangeli, N. J. Meropol: Age and sex are independent predictors of 5-fluorouracil toxicity. Cancer 75 (1995), 11-17.
20. World Health Organisation: WHO Handbook for reporting results of cancer treatment. Offset Publication No. 48, WHO, Genf 1979.