A positively charged surface patch is important for hainantoxin-IV binding to voltage-gated sodium channels

Journal of Peptide Science

Volumn 18, Issue 10, 2012, Pages 643-649

  Liu, Yu ^a,b   Li, Dan ^a   Wu, Zhe ^b   Li, Jing ^a   Nie, Dongsong ^b   Xiang, Yang ^b   Liu, Zhonghua ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

^b HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Hainantoxin IV; Interaction; Mutant; Voltage gated sodium channel

Indexed keywords

AMINO ACID DERIVATIVE; HAINANTOXIN 4 H28D; HAINANTOXIN 4 K32A; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; FEMALE; GANGLIA, SPINAL; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS; SOLID PHASE EXTRACTION; SPIDER VENOMS; SPIDERS; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

ARANEAE; ORNITHOCTONUS HAINANA; RATTUS;

EID: 84866446819     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.2451     Document Type: Article

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