Interleukin-1α induces immunosuppression by mesenchymal stem cells promoting the growth of prostate cancer cells

Molecular Medicine Reports

Volumn 6, Issue 5, 2012, Pages 955-960

  Cheng, Jiwen ^a   Li, Ling ^a   Liu, Yan ^a   Wang, Zhirou ^a   Zhu, Xiaodong ^a   Bai, Xianzhong ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Interleukin 1 ; Mesenchymal stem cells; Prostate cancer cell; Transforming growth factor

Indexed keywords

RECOMBINANT INTERLEUKIN 1ALPHA; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL GROWTH; CONTROLLED STUDY; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOSURVEILLANCE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PROSTATE CANCER; TUMOR MICROENVIRONMENT; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; IMMUNOSUPPRESSION; INTERLEUKIN-1ALPHA; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; PROSTATIC NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HOMOLOGOUS; UP-REGULATION;

EID: 84866438376     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1019     Document Type: Article

References (24)

1. Deans RJ and Moseley AB: Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 28: 875-884, 2000.
2. Bianco P and Gehron Robey P: Marrow stromal stem cells. J Clin Invest 105: 1663-1668, 2000. (Pubitemid 30421745)
3. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S and Marshak DR: Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147, 1999. (Pubitemid 29282067)
4. Barry FP and Murphy JM: Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol 36: 568-584, 2004. (Pubitemid 38324589)
5. Bianco P, Robey PG and Simmons PJ: Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell 2: 313-319, 2008. (Pubitemid 351467394)
6. Anjos-Afonso F and Bonnet D: Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment. Blood 109: 1298-1306, 2007. (Pubitemid 46220683)
7. In 't Anker PS, Scherjon SA, Kleijburg-van der Keur C, de Groot-Swings GM, Claas FH, Fibbe WE and Kanhai HH: Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells 22: 1338-1345, 2004. (Pubitemid 39636409)
8. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP and Hedrick MH: Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7: 211-228, 2001. (Pubitemid 32295155)
9. Sato K, Ozaki K, Oh I, Meguro A, Hatanaka K, Nagai T, Muroi K and Ozawa K: Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 109: 228-234, 2007. (Pubitemid 46053063)
10. Rasmusson I, Ringdén O, Sundberg B and Le Blanc K: Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms. Exp Cell Res 305: 33-41, 2005. (Pubitemid 40380651)
11. Krampera M, Glennie S, Dyson J, Scott D, Laylor R, Simpson E and Dazzi F: Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 101: 3722-3729, 2003. (Pubitemid 36857965)
12. Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, Grisanti S and Gianni AM: Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99: 3838-3843, 2002. (Pubitemid 34534559)
13. Koç ON, Day J, Nieder M, Gerson SL, Lazarus HM and Krivit W: Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH). Bone Marrow Transplant 30: 215-222, 2002. (Pubitemid 35023593)
14. Djouad F, Fritz V, Apparailly F, Louis-Plence P, Bony C, Sany J, Jorgensen C and Noël D: Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum 52: 1595-1603, 2005.
15. Zappia E, Casazza S, Pedemonte E, Benvenuto F, Bonanni I, Gerdoni E, Giunti D, Ceravolo A, Cazzanti F, Frassoni F, et al: Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood 106: 1755-1761, 2005. (Pubitemid 41208591)
16. Nakamizo A, Marini F, Amano T, Khan A, Studeny M, Gumin J, Chen J, Hentschel S, Vecil G, Dembinski J, et al: Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 65: 3307-3318, 2005. (Pubitemid 40524615)
17. Hall BM, Fortney JE, Taylor L, Wood H, Wang L, Adams S, Davis S and Gibson LF: Stromal cells expressing elevated VCAM-1 enhance survival of B lineage tumor cells. Cancer Lett 207: 229-239, 2004. (Pubitemid 38457045)
18. Djouad F, Plence P, Bony C, Tropel P, Apparailly F, Sany J, Noël D and Jorgensen C: Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 102: 3837-3844, 2003. (Pubitemid 37409409)
19. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide D, Combs CA, Hall G, et al: Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med 203: 1235-1247, 2006. (Pubitemid 43736593)
20. Xu W, Zhang X, Qian H, Zhu W, Sun X, Hu J, Zhou H and Chen Y: Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro. Exp Biol Med (Maywood) 229: 623-631, 2004. (Pubitemid 38878907)
21. D'Agostino B, Sullo N, Siniscalco D, De Angelis A and Rossi F: Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease. Expert Opin Biol Ther 10: 681-687, 2010.
22. Mazzini L, Ferrero I, Luparello V, Rustichelli D, Gunetti M, Mareschi K, Testa L, Stecco A, Tarletti R, Miglioretti M, et al: Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: a phase I clinical trial. Exp Neurol 223: 229-237, 2010.
23. Loebinger MR, Eddaoudi A, Davies D and Janes SM: Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. Cancer Res 69: 4134-4142, 2009.
24. Liu Y, Han ZP, Zhang SS, Jing YY, Bu XX, Wang CY, Sun K, Jiang GC, Zhao X, Li R, et al: Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer. J Biol Chem 286: 25007-25015, 2011.