Targeted analyte detection by standard addition improves detection limits in matrix-assisted laser desorption/ionization mass spectrometry

Analytical Chemistry

Volumn 84, Issue 18, 2012, Pages 7626-7632

  Toghi Eshghi, Shadi ^a   Li, Xingde ^a   Zhang, Hui ^b  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTE CONCENTRATION; ANALYTE DETECTION; ANALYTES; CHEMICAL NOISE; CLINICAL SAMPLES; COMPLEX BACKGROUND; COMPLEX SAMPLES; DETECTION LIMITS; DETECTOR SENSITIVITY; EFFECTIVE TOOL; HARDWARE MODIFICATIONS; LIMIT OF DETECTION; MATRIX ASSISTED LASER DESORPTION/IONIZATION; MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY; NOISE LEVELS; OPTIMUM CONCENTRATION; QUANTITATIVE METHOD; STANDARD ADDITION; TARGET ANALYTES;

CHEMICAL DETECTION; MASS SPECTROMETRY; MOLECULES; PEPTIDES;

DETECTORS;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 15); AMYLOID BETA-PROTEIN (1-15); ANGIOTENSIN I; ANGIOTENSIN II; PEPTIDE; PEPTIDE FRAGMENT;

ARTICLE; LIMIT OF DETECTION; MASS SPECTROMETRY; STANDARD;

AMYLOID BETA-PEPTIDES; ANGIOTENSIN I; ANGIOTENSIN II; LIMIT OF DETECTION; PEPTIDE FRAGMENTS; PEPTIDES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84866434185     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac301423f     Document Type: Article

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