Development of Transgenic Mice Containing an Introduced Stop Codon on the Human Methylmalonyl-CoA Mutase Locus

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Buck, Nicole E ^a   Dashnow, Harriet ^a   Pitt, James J ^a,b   Wood, Leonie R ^a   Peters, Heidi L ^a,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLMALONIC ACID; METHYLMALONYL COENZYME A MUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL CHROMOSOME; CHROMOSOME 3; CONTROLLED STUDY; DEATH; FEMALE; GENE; GENE DUPLICATION; GENE LOCUS; GENE MUTATION; GENOTYPE; HEMIZYGOTE; HETEROZYGOTE; KNOCKOUT MOUSE; MALE; METHYLMALONIC ACID TISSUE LEVEL; METHYLMALONIC ACIDEMIA; METHYLMALONIC ACIDURIA; METHYLMALONYL COA MUTASE GENE; MOUSE; NONHUMAN; PHENOTYPE; STOP CODON; TISSUE LEVEL; TRANSGENE; TRANSGENIC MOUSE;

AMINO ACID METABOLISM, INBORN ERRORS; ANIMALS; BREEDING; CODON, NONSENSE; DISEASE MODELS, ANIMAL; FEMALE; GENE ORDER; GENE TARGETING; HOMOLOGOUS RECOMBINATION; HUMANS; MALE; METHYLMALONIC ACID; METHYLMALONYL-COA MUTASE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROINJECTIONS; TRANSGENES;

BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS;

EID: 84866418623     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044974     Document Type: Article

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