Blockade of astrocytic glutamate uptake in the prefrontal cortex induces anhedonia

Neuropsychopharmacology

Volumn 37, Issue 11, 2012, Pages 2467-2475

  John, Catherine S ^a   Smith, Karen L ^a   Van'T Veer, Ashlee ^a   Gompf, Heinrich S ^a   Carlezon, William A ^a   Cohen, Bruce M ^a   Ngür, Dost ^a   Bechtholt Gompf, Anita J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

anhedonia; astrocytes; dihydrokainic acid; GLT 1; glutamate; prefrontal cortex

Indexed keywords

DIHYDROKAINIC ACID; VESICULAR GLUTAMATE TRANSPORTER 1;

ANHEDONIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DEPRESSION; ELECTROENCEPHALOGRAM; LATENT PERIOD; LOCOMOTION; MALE; MICROINJECTION; MOOD; MOTOR DYSFUNCTION; NONHUMAN; PHENOTYPE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SEIZURE; SELF STIMULATION; SUGAR INTAKE; SYMPTOM;

ANALYSIS OF VARIANCE; ANHEDONIA; ANIMALS; ASTROCYTES; BRAIN WAVES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; EXCITATORY AMINO ACID AGONISTS; FOOD PREFERENCES; GLUTAMIC ACID; KAINIC ACID; MALE; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; SELF STIMULATION; SUCROSE;

EID: 84866401401     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.105     Document Type: Article

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