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EMBO Journal

Volumn 31, Issue 18, 2012, Pages 3647-3649

Down syndrome DSCR1 causes spine pathology via the Fragile X-related protein FMRP

(1) Roselli, Francesco a

a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

COFILIN; DOWN SYNDROME CRITICAL REGION 1 PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; MESSENGER RNA; MICRORNA; PROTEIN; RNA INDUCED SILENCING COMPLEX; SAPA PROTEIN; SCAFFOLD PROTEIN; SHANK PROTEIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; BRAIN FUNCTION; CHROMOSOME 21Q; DOWN REGULATION; DOWN SYNDROME; GENE OVEREXPRESSION; HUMAN; INTELLECTUAL IMPAIRMENT; KNOCKOUT GENE; MEMORY DISORDER; MORPHOGENESIS; NERVE CELL PLASTICITY; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SPINE DISEASE; SYNAPSE;

ANIMALS; DENDRITIC SPINES; FRAGILE X MENTAL RETARDATION PROTEIN; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE PROTEINS;

EID: 84866387953 PISSN: 02614189 EISSN: 14602075 Source Type: Journal
DOI: 10.1038/emboj.2012.239 Document Type: Article

Times cited : (5)

References (10)

1
- 82555196668
- Mutations causing syndromic autism define an axis of synaptic pathophysiology
- Auerbach BD, Osterweil EK, Bear MF (2011) Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature 480: 63-68
- (2011) Nature , vol.480 , pp. 63-68
- Auerbach, B.D.¹ Osterweil, E.K.² Bear, M.F.³

2
- 65349085563
- Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
- Hotulainen P, Llano O, Smirnov S, Tanhuanpää K, Faix J, Rivera C, Lappalainen P (2009) Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol 185: 323-339
- (2009) J Cell Biol , vol.185 , pp. 323-339
- Hotulainen, P.¹ Llano, O.² Smirnov, S.³ Tanhuanpää, K.⁴ Faix, J.⁵ Rivera, C.⁶ Lappalainen, P.⁷

3
- 49149088555
- Reversal of learning deficits in a Tsc2 +-mouse model of tuberous sclerosis
- Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, Silva AJ (2008) Reversal of learning deficits in a Tsc2 +-mouse model of tuberous sclerosis. Nat Med 14: 843-848
- (2008) Nat Med , vol.14 , pp. 843-848
- Ehninger, D.¹ Han, S.² Shilyansky, C.³ Zhou, Y.⁴ Li, W.⁵ Kwiatkowski, D.J.⁶ Ramesh, V.⁷ Silva, A.J.⁸

4
- 84863545043
- Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
- Martin KR, Corlett A, Dubach D, Mustafa T, Coleman HA, Parkington HC, Merson TD, Bourne JA, Porta S, Arbonés ML, Finkelstein DI, Pritchard MA (2012) Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory. Hum Mol Genet 21: 3025-3041
- (2012) Hum Mol Genet , vol.21 , pp. 3025-3041
- Martin, K.R.¹ Corlett, A.² Dubach, D.³ Mustafa, T.⁴ Coleman, H.A.⁵ Parkington, H.C.⁶ Merson, T.D.⁷ Bourne, J.A.⁸ Porta, S.⁹ Arbonés, M.L.¹⁰ Finkelstein, D.I.¹¹ Pritchard, M.A.¹²

5
- 84859628864
- Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice
- Michalon A, Sidorov M, Ballard TM, Ozmen L, Spooren W, Wettstein JG, Jaeschke G, Bear MF, Lindemann L (2012) Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. Neuron 74: 49-56
- (2012) Neuron , vol.74 , pp. 49-56
- Michalon, A.¹ Sidorov, M.² Ballard, T.M.³ Ozmen, L.⁴ Spooren, W.⁵ Wettstein, J.G.⁶ Jaeschke, G.⁷ Bear, M.F.⁸ Lindemann, L.⁹

6
- 79958045841
- Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling
- Muddashetty RS, Nalavadi VC, Gross C, Yao X, Xing L, Laur O, Warren ST, Bassell GJ (2011) Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. Mol Cell 42: 673-688
- (2011) Mol Cell , vol.42 , pp. 673-688
- Muddashetty, R.S.¹ Nalavadi, V.C.² Gross, C.³ Yao, X.⁴ Xing, L.⁵ Laur, O.⁶ Warren, S.T.⁷ Bassell, G.J.⁸

7
- 78449259794
- Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome
- Osterweil EK, Krueger DD, Reinhold K, Bear MF (2010) Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome. J Neurosci 30: 15616-15627
- (2010) J Neurosci , vol.30 , pp. 15616-15627
- Osterweil, E.K.¹ Krueger, D.D.² Reinhold, K.³ Bear, M.F.⁴

8
- 67651124806
- Molecular genetic analysis of Down syndrome
- Patterson D (2009) Molecular genetic analysis of Down syndrome. Hum Genet 126: 195-214
- (2009) Hum Genet , vol.126 , pp. 195-214
- Patterson, D.¹

9
- 84862777306
- Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome
- Ronesi JA, Collins KA, Hays SA, Tsai NP, Guo W, Birnbaum SG, Hu JH, Worley PF, Gibson JR, Huber KM (2012) Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome. Nat Neurosci 15: 431-440
- (2012) Nat Neurosci , vol.15 , pp. 431-440
- Ronesi, J.A.¹ Collins, K.A.² Hays, S.A.³ Tsai, N.P.⁴ Guo, W.⁵ Birnbaum, S.G.⁶ Hu, J.H.⁷ Worley, P.F.⁸ Gibson, J.R.⁹ Huber, K.M.¹⁰

10
- 84866417191
- DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis
- Wang W, Zhu JZ, Chang KT, Min K-T (2012) DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis. EMBO J 31 : 3655-3666
- (2012) EMBO J , vol.31 , pp. 3655-3666
- Wang, W.¹ Zhu, J.Z.² Chang, K.T.³ Min, K.-T.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.