Effect of permeation enhancers on the penetration mechanism of transfersomal gel of ketoconazole

Journal of Advanced Pharmaceutical Technology and Research

Volumn 3, Issue 2, 2012, Pages 112-116

  Rajan, Reshmy ^a   Vasudevan, Deepa T ^a  

^a AMRITA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Edge activator; Ketoconazole; Lecithin; Permeation enhancers; Transfersomes

Indexed keywords

DRUG CARRIER; ESSENTIAL OIL; EUCALYPTUS OIL; KETOCONAZOLE; PENETRATION ENHANCING AGENT; PEPPERMINT OIL; TRANSFERSOME; TURPENTINE OIL; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; GEL; PRIORITY JOURNAL; SKIN PENETRATION; TRANSDERMAL DRUG ADMINISTRATION;

EID: 84866374031     PISSN: 22314040     EISSN: 09762094     Source Type: Journal    
DOI: 10.4103/2231-4040.97286     Document Type: Article

References (18)

1. Ketoconazole: Drug Information Provided by Lexi Comp: Merck manual Professional. (available from: http://Lexi-Comp. com [Last cited on 2012 Feb 18]).
2. Drug Information Online, available from: Http://www. Drugs. com [Last accessed on 2011 Nov 24]
3. Langer R. Transdermal drug delivery: Past progress, current status and future prospects. Adv Drug Deliv Rev 2004;56:557-8 (Pubitemid 38326932)
4. Cooper ER. Euro Pat. Appl. Penetrating Topical Pharmaceutical Compositions Containing N-(2 hydroxyethyl) pyrrolidone. EP 129285 A2, 27 Dec 1984; Appl. 84/200823, 12 Jun 1984: US Appl. 506273, 21 Jun 1983
5. Aqil M, Ahad A, Sulthana Y, Ali A. status of terpenes as skin Penetration enhancers. Drug Discov Today 2007;12:1061-7 (Pubitemid 350180560)
6. Biruss B, Khaliq H, Valenta C. Evaluation of an Eucalyptus oil containing topical drug delivery system for selected steroid hormones. Int J Pharm 2007;328:142-51 (Pubitemid 44880573)
7. Femenia-Font A, Balaguer-Fernandez C, Merino V, Rodilla V, Lopez-Castellano A. Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate. Eur JPharmBiopharm2005;61:50-5 (Pubitemid 41096688)
8. Narishetty ST, Panchagnula R. Effect of L Menthol and 1,8-cineole on Phase behaviour andmolecular organization of SC lipids and skin permeation of Zidovdine. J Control Release 2005;102:59-70 (Pubitemid 40093776)
9. Yamane MA, Williams AC, Barry BW. Effects of terpenes and oleic acids as skin penetration enhancers towards 5-Flurouracil as assessed with time;permeation, partitioning and differential scanning calorimetry. Int J Pharm 1995;116:237-51
10. Jain CP, Vyas SP, Dixit VK. Niosomal system for delivery of Rifampicin to lymphatics. Indian J Pharm Sci 2006;68:575-8 (Pubitemid 46087763)
11. Elsayed MM, Abdallah OY, Nagar VF. Deformable liposomes and ethosomes: mechanism of enhanced skin delivery. Int J Pharm 2006;332:60-6 (Pubitemid 44348860)
12. Dodov MG, Simonoska M, Goracinova K. Formulation and characterisation of 5-fluorouracil loaded liposomes. Bull Chem Technol Macedonia; 2005;24:59-65
13. Liberman HA, Rieger MM, Banker GS. Pharmaceutical Dosage Form, Disperse Systems. Vol. 3. New York: Marcel Dekker; 1989. p. 594
14. Deepa TV, Kavitha RD, Gopalakrishnan S, Ravikumar KG, Sundaram KR. Development and validation of spectrophotometric method for chrysophanol in gel formulations. Int J Drug Dev Res 2010;2:2
15. Suwantong O, Opanasopit P, Ruktanonchai U, Supaphol P. Electrospun cellulose acetate fiber mats containing curcumin and release characteristic of the herbal substance. Polymer 2007;48:7546-57 (Pubitemid 350199671)
16. Siddaramaiah, Kumar P, Divya K, Mhemavathi B, Manjula D. Chitosan/HPMC polymer blends for developing transdermal drug delivery systems. J MacromSci Part A- Pure Appl Chem 2006;43:601-7
17. Mei Z, Chen H, Wang T, Yang Y, Yang X. Solid lipid nanoparticle and microemulsion for topical delivery of triptolide. Eur J Pharm Biopharm 2003;56:189-96 (Pubitemid 37072102)
18. Shah KA, Date AA, Joshi MD, Patravale VB. Solid lipid nanoparticles (SLN) of tretinoin: Potential in topical delivery. Int J Pharm 2007;345:163-71. (Pubitemid 350087549)