Inpatient Enoxaparin and Outpatient Aspirin Chemoprophylaxis Regimen After Primary Hip and Knee Arthroplasty: A Preliminary Study

Journal of Arthroplasty

Volumn 27, Issue 9, 2012, Pages 1594-1598

  Hamilton, Stephen C ^a   Whang, William W ^b   Anderson, Blake J ^a   Bradbury, Thomas L ^a   Erens, Greg A ^a   Roberson, James R ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Gould Medical Foundation   (United States)

Author keywords

Aspirin; Enoxaparin; Primary joint arthroplasty; Thromboprophylaxis

Indexed keywords

ACETYLSALICYLIC ACID; ENOXAPARIN;

ADULT; ARTICLE; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; ERYTHROCYTE TRANSFUSION; FEMALE; HIP ARTHROPLASTY; HOSPITAL CARE; HUMAN; KNEE ARTHROPLASTY; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTPATIENT CARE; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE INFECTION; POSTOPERATIVE THROMBOSIS; RETROSPECTIVE STUDY; THROMBOSIS PREVENTION; TREATMENT DURATION;

ANTICOAGULANTS; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; ASPIRIN; BODY MASS INDEX; ENOXAPARIN; FEMALE; HUMANS; INPATIENTS; LENGTH OF STAY; MALE; MIDDLE AGED; OUTPATIENTS; POSTOPERATIVE COMPLICATIONS; PULMONARY EMBOLISM; RETROSPECTIVE STUDIES; VENOUS THROMBOSIS;

EID: 84866370828     PISSN: 08835403     EISSN: 15328406     Source Type: Journal    
DOI: 10.1016/j.arth.2012.02.006     Document Type: Article

References (43)

1. Markel D.C., York S., Liston M.J., AAHKS Research Committee, et al. Venous Thromboembolism. Management by American Association of Hip and Knee Surgeons. J Arthroplasty 2010, 1:25.
2. Haas S.B., Barrack R.L., Westrich G., et al. Venous thromboembolic disease after total hip and knee arthroplasty. J Bone Joint Surg Am 2008, 90A:2764.
3. Sugano N., Hidenobu M., et al. Clinical efficacy of mechanical thromboprophylaxis without anticoagulant drugs for elective hip surgery in an Asian population. J Arthroplasty 2009, 24:1254.
4. Lachiewicz P.F., Kelley S.S., Haden L.R. Two mechanical devices for prophylaxis of thromboembolism after total knee arthroplasty. A prospective randomized study. J Bone Joint Surg Br 2004, 86:1137.
5. Geerts W.H., Bergqvist D., Pineo G.F., et al. Prevention of thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition). Chest 2008, 133:381S.
6. Johanson N.A., Lachiewicz P.F., Lieberman J.R., et al. Prevention of symptomatic pulmonary embolism in patients undergoing total hip or knee arthroplasty. JAAOS 2009, 17:183.
7. Bhattacharyya T., Freibera A.A., et al. Measuring the report card: the validity of pay-for-performance metrics in orthopedic surgery. Health Aff 2009, 28:526.
8. Upadhyay A., York S., et al. Medical malpractice in hip and knee arthroplasty. J Arthroplasty 2007, 22(suppl 6):2.
9. Leclerc J.R., Gent M., et al. The incidence of symptomatic venous thromboembolism during and after prophylaxis during and after prophylaxis with enoxaparin. Arch Intern Med 1998, 158:873.
10. Skedgel C., Goeree R., et al. The cost-effectiveness of extended-duration antithrombotic prophylaxis after total hip arthroplasty. J Bone Joint Surg Am 2007, 89A:819.
11. Comp P.C., Spiro T.E., et al. Prolonged enoxaparin therapy to prevent venous thromboembolism after primary hip or knee replacement. J Bone Joint Surg Am 2001, 83A:336.
12. Stephen R., Burnett J., et al. Failure of the American College of Chest Physicians-1A protocol for Lovenox in clinical outcomes for thromboembolic prophylaxis. J Arthroplasty 2007, 22:317.
13. Sharrock N.E., Della Valle A.G., et al. Potent anticoagulants are associated with a higher all-cause mortality rate after hip and knee arthroplasty. Clin Orthop Relat Res 2008, 466:714.
14. Bozic K.J., Vail T.P., et al. Does aspirin have a role in venous thromboembolism prophylaxis in total knee arthroplasty patients?. J Arthroplasty 2009, 0:1.
15. Dorr L.D., Gendelman V., et al. Multimodal thromboprophylaxis for total hip and knee arthroplasty based on risk assessment. J Bone Joint Surg Am 2007, 89:2648.
16. Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin. Pulmonary Embolism Prevention (PEP) trial. Lancet 2000, 355:1295.
17. Harris W.H., et al. Aspirin prophylaxis of venous thromboembolism after total hip replacement. N Engl J Med 1977, 297:1246.
18. McKenna R., et al. Prevention of venous thromboembolism after total knee replacement by high dose aspirin or intermittent calf and thigh compression. Br Med J 1980, 280:514.
19. Lotke P.A., Lonner J.H. The benefit of aspirin chemoprophylaxis for thromboembolism after total knee arthroplasty. Clin Orthop Relat Res 2006, 452:175.
20. Lachiewicz P.F., Solieau E.S. Mechanical calf compression and aspirin prophylaxis for total knee arthroplasty. Clin Orthop Relat Res 2007, 464:61.
21. Bratzler D.W. Development of national performance measures on the prevention and treatment of venous thromboembolism. J Thromb Thrombolysis 2010, 29:148.
22. Yoon R.S., Nellans K.W., et al. Patient education before hip or knee arthroplasty lowers length of stay. J Arthroplasty 2010, 25:547.
23. White R.H., Romano P.S., Zhou H., et al. Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty. Arch Intern Med 1998, 158:1525.
24. Gonzalez Della Valle G., Serota A., et al. Venous thromboembolism is rare with a multimodal prophylaxis protocol after total hip arthroplasty. Clin Orthop Relat Res 2006, 444:146.
25. Warwick D., Williams M.H., Bannister G.C. Death and thromboembolic disease after total hip replacement. A series of 1162 cases with no routine chemical prophylaxis. J Bone Joint Surg Am 1995, 77:6.
26. Kim Y.H., Oh S.H., Kim J.S. Incidence and natural history of deep-vein thrombosis after total hip arthroplasty: a prospective and randomized clinical study. J Bone Joint Surg Br 2003, 85:661.
27. Colwell C.W., Froimson M.I., Mont M.A., et al. Thrombosis prevention after total hip arthroplasty. A prospective, randomized trial comparing a mobile compression device with low molecular weight heparin. J Bone Joint Surg Am 2010, 92:527.
28. Colwell C.W., Spiro T.E. Efficacy and safety of enoxaparin to prevent deep vein thrombosis after hip arthroplasty. Clin Orthop Relat Res 1995, 319:219.
29. Fitzgerald R.H., Spiro T.E., Trowbridge A.A., et al. Prevention of venous thromboembolic disease following primary total knee arthroplasty: a randomized multicenter, open label, parallel group comparison of enoxaparin and warfarin. J Bone Joint Surg Am 2001, 83:900.
30. Eikelboom J.W., Karthikeyan G., Fagel N., et al. American Association of Orthopedic Surgeons and American College of Chest Physicians Guidelines for venous thromboembolism prevention in hip and knee arthroplasty differ. What are the implications for clinicians and patients?. Chest 2009, 135:513.
31. Kwong L.M., Happe L.E., Horblyuk R., et al. Decreased venous thromboembolism with injectable vs oral anticoagulation after discharge for major orthopedic surgery. J Arthroplasty 2008, 23:25.
32. Novicoff W.M., Brown T.E., et al. Mandated venous thromboembolism prophylaxis. Possible adverse outcomes. J Arthroplasty 2008, 23:15.
33. Neviaser A.S., Chang C., et al. High incidence of complications from enoxaparin treatment after arthroplasty. Clin Orthop Relat Res 2010, 468:115.
34. Patel V.P., Walsh M., et al. Factors associated with prolonged wound drainage after primary total hip and knee arthroplasty. J Bone Joint Surg Am 2007, 89:33.
35. Eikelboom J.W., Quinlan D.J., Douketis J.D. Extended-duration prophylaxis against venous thromboembolism after total hip or knee replacement: a meta-analysis of the randomized trials. Lancet 2001, 358:9.
36. McAndrew C.M., Fitzgerald S.J., Kray M.J., et al. Incidence of postthrombotic syndrome in patients undergoing primary total knee arthroplasty for osteoarthritis. Clin Orthop Relat Res 2010, 268:178.
37. Jameson S.S., Bottle A., et al. The impact of national guidelines for the prophylaxis of venous thromboembolism on the complications of arthroplasty of the lower limb. J Bone Joint Surg Br 2010, 92:123.
38. Callaghan J.J., Warth L.C., et al. Evaluation of deep venous thrombosis prophylaxis in low risk patients undergoing total knee arthroplasty. J Arthroplasty 2008, 23:20.
39. Brown G.A. Venous thromboembolism prophylaxis after major orthopaedic surgery. A pooled analysis of randomized controlled trials. J Arthroplasty 2009, 24(suppl 6):77.
40. Larsen K., Hansen T.B., et al. Cost-effectiveness of accelerated perioperative care and rehabilitation after total hip and knee arthroplasty. J Bone Joint Surg Am 2009, 91:761.
41. Sarasin F.P., Bounameaux H. Out of hospital antithrombotic prophylaxis after total hip replacement: low-molecular-weight heparin, warfarin, aspirin, or nothing. A cost effectiveness analysis. Thomb Haemost 2002, 87:586.
42. Dhupar S., Iorio R., Healy W.L., et al. A comparison of discharge and two week duplex ultrasound screening protocols for deep venous thrombosis detection following total joint arthroplasty. J Bone Joint Surg Am 2006, 88:2380.
43. American Academy of Orthopaedic Surgeons clinical guideline on prevention of symptomatic pulmonary embolism in patients undergoing total hip or knee arthroplasty 2007, 63. American Academy of Orthopaedic Surgeons (AAOS), Rosemont (IL).