Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis

Diabetologia

Volumn 55, Issue 8, 2012, Pages 2193-2204

  Islam, M ^a   Jafar, T H ^a,b   Wood, A R ^c   De Silva, N M G ^c   Caulfield, M ^d   Chaturvedi, N ^e   Frayling, T M ^c  

^a AGA KHAN UNIVERSITY   (Pakistan)

^b AGA KHAN UNIVERSITY HOSPITAL   (Pakistan)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^e NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Fasting glucose; Genetic risk scores; Instrumental variable analysis; Mendelian randomisation; Triacylglycerol; Type 2 diabetes

Indexed keywords

GLUCOSE; TRIACYLGLYCEROL;

ADULT; ALLELE; ASIAN; BODY MASS; CAUCASIAN; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ETHNIC DIFFERENCE; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENDELIAN RANDOMIZATION ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PAKISTAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SCORING SYSTEM; SYSTOLIC BLOOD PRESSURE;

ANALYSIS OF VARIANCE; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FASTING; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HUMANS; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MIDDLE AGED; PAKISTAN; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TRIGLYCERIDES;

EID: 84866360528     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2560-y     Document Type: Review

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