Degradation kinetics of an aspartyl-tripeptide-derived diketopiperazine under forced conditions

Journal of Pharmaceutical Sciences

Volumn 101, Issue 11, 2012, Pages 4178-4190

  Brückner, Christin ^a   Fahr, Alfred ^a   Imhof, Diana ^b   Scriba, Gerhard K E ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Analytical chemistry; Aspartic acid; Capillary electrophoresis; Diketopiperazine; Enantiomerization; Isoaspartic acid; Isomerization; Kinetics; Peptides; Stability

Indexed keywords

ASPARTIC ACID; ASPARTYL DIKETOPIPERAZINE DERIVATIVE; PIPERAZINEDIONE; SUCCINIMIDE; TRIPEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CAPILLARY ELECTROPHORESIS; DEGRADATION KINETICS; DIASTEREOISOMER; DRUG STABILITY; ENANTIOMER; EPIMERIZATION; HYDROLYSIS; ISOMERIZATION; PH;

EID: 84866360424     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23272     Document Type: Article

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