The clinical determinants of malignant transformation in oral epithelial dysplasia

Oral Oncology

Volumn 48, Issue 10, 2012, Pages 969-976

  Ho, M W ^a   Risk, J M ^b   Woolgar, J A ^c   Field, E A ^d   Field, J K ^b,d   Steele, J C ^d   Rajlawat, B P ^d   Triantafyllou, A ^c   Rogers, S N ^a,e   Lowe, D ^e   Shaw, R J ^a,b  

^a UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^d LIVERPOOL UNIVERSITY DENTAL HOSPITAL   (United Kingdom)

^e EDGE HILL UNIVERSITY   (United Kingdom)

Author keywords

Malignant transformation; Oral dysplasia; Oral squamous cell carcinoma; Smoking

Indexed keywords

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; DISEASE COURSE; DISEASE SEVERITY; EPITHELIUM DYSPLASIA; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; MOUTH CANCER; OBSERVATIONAL STUDY; ORAL EPITHELIAL DYSPLASIA; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; REMISSION; SMOKING;

ALCOHOL DRINKING; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; LEUKOPLAKIA, ORAL; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MOUTH NEOPLASMS; PRECANCEROUS CONDITIONS; RISK FACTORS; SMOKING; TREATMENT OUTCOME;

EID: 84866354303     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2012.04.002     Document Type: Article

References (28)

1. M. Brennan, C.A. Migliorati, P.B. Lockhart, D. Wray, I. Al-Hashimi, and T. Axell Management of oral epithelial dysplasia: a review Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103 Suppl. 2007 e1 e12 S19
2. I. van dW Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management Oral Oncol 45 4-5 2009 317 323
3. M.A. Jaber, S.R. Porter, P. Speight, J.W. Eveson, and C. Scully Oral epithelial dysplasia: clinical characteristics of western European residents Oral Oncol 39 6 2003 589 596
4. L. Barnes, J.W. Eveson, P. Reichart, and D. Sidransky World Health Organization classification of tumours. Pathology and genetics. Head and neck tumours 2005 World Health Organization
5. H. Lumerman, P. Freedman, and S. Kerpel Oral epithelial dysplasia and the development of invasive squamous cell carcinoma Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79 3 1995 321 329
6. H.M. Mehanna, T. Rattay, J. Smith, and C.C. McConkey Treatment and follow-up of oral dysplasia - a systematic review and meta-analysis Head Neck 31 12 2009 1600 1609
7. S. Silverman Jr., M. Gorsky, and F. Lozada Oral leukoplakia and malignant transformation. A follow-up study of 257 patients Cancer 53 3 1984 563 568
8. P.G. Arduino, A. Surace, M. Carbone, A. Elia, G. Massolini, and S. Gandolfo Outcome of oral dysplasia: a retrospective hospital-based study of 207 patients with a long follow-up J Oral Pathol Med 38 6 2009 540 544
9. P.S. Ho, P.L. Chen, S. Warnakulasuriya, T.Y. Shieh, Y.K. Chen, and I.Y. Huang Malignant transformation of oral potentially malignant disorders in males: a retrospective cohort study BMC Cancer 9 2009 260
10. K.P. Schepman, E.H. van der Meij, L.E. Smeele, and I. van dW Malignant transformation of oral leukoplakia: a follow-up study of a hospital-based population of 166 patients with oral leukoplakia from The Netherlands Oral Oncol 34 4 1998 270 275
11. I. van dW, K.P. Schepman, E.H. van der Meij, and L.E. Smeele Oral leukoplakia: a clinicopathological review Oral Oncol 33 5 1997 291 301
12. L. Zhang, C.F. Poh, W.L. Lam, J.B. Epstein, X. Cheng, and X. Zhang Impact of localized treatment in reducing risk of progression of low-grade oral dysplasia: molecular evidence of incomplete resection Oral Oncol 37 6 2001 505 512
13. I.R. Kramer, N. El-Labban, and K.W. Lee The clinical features and risk of malignant transformation in sublingual keratosis Br Dent J 144 6 1978 171 180
14. M.A. Pogrel Sublingual keratosis and malignant transformation J Oral Pathol 8 3 1979 176 178
15. P. Holmstrup, P. Vedtofte, J. Reibel, and K. Stoltze Long-term treatment outcome of oral premalignant lesions Oral Oncol 42 5 2006 461 474
16. S.S. Napier, C.G. Cowan, T.A. Gregg, M. Stevenson, P.J. Lamey, and P.G. Toner Potentially malignant oral lesions in Northern Ireland: size (extent) matters Oral Dis 9 3 2003 129 137
17. W. Liu, Z.X. Bao, L.J. Shi, G.Y. Tang, and Z.T. Zhou Malignant transformation of oral epithelial dysplasia: clinicopathological risk factors and outcome analysis in a retrospective cohort of 138 cases Histopathology 59 4 2011 733 740
18. L.S. Hansen, J.A. Olson, and S. Silverman Jr. Proliferative verrucous leukoplakia. A long-term study of thirty patients Oral Surg Oral Med Oral Pathol 60 3 1985 285 298
19. R.J. Cabay, T.H. Morton Jr., and J.B. Epstein Proliferative verrucous leukoplakia and its progression to oral carcinoma: a review of the literature J Oral Pathol Med 36 5 2007 255 261
20. O. Hamadah, M.L. Goodson, and P.J. Thomson Clinicopathological behaviour of multiple oral dysplastic lesions compared with that of single lesions Br J Oral Maxillofac Surg 48 7 2010 503 506
21. J.J. Marley, C.G. Cowan, P.J. Lamey, G.J. Linden, N.W. Johnson, and K.A. Warnakulasuriya Management of potentially malignant oral mucosal lesions by consultant UK oral and maxillofacial surgeons Br J Oral Maxillofac Surg 34 1 1996 28 36
22. G. Lodi, A. Sardella, C. Bez, F. Demarosi, and A. Carrassi Interventions for treating oral leukoplakia Cochrane Database Syst Rev 4 2006 CD001829
23. S. Silverman, K. Bhargava, L.W. Smith, and A.M. Malaowalla Malignant transformation and natural history of oral leukoplakia in 57,518 industrial workers of Gujarat, India Cancer 38 4 1976 1790 1795
24. O. Kujan, R.J. Oliver, A. Khattab, S.A. Roberts, N. Thakker, and P. Sloan Evaluation of a new binary system of grading oral epithelial dysplasia for prediction of malignant transformation Oral Oncol 42 10 2006 987 993
25. J.J. Lee, W.K. Hong, W.N. Hittelman, L. Mao, R. Lotan, and D.M. Shin Predicting cancer development in oral leukoplakia: ten years of translational research Clin Cancer Res 6 5 2000 1702 1710
26. C.F. Poh, Y. Zhu, E. Chen, K.W. Berean, L. Wu, and L. Zhang Unique FISH patterns associated with cancer progression of oral dysplasia J Dent Res 91 1 2012 52 57
27. N.K. Cervigne, P.P. Reis, J. Machado, B. Sadikovic, G. Bradley, and N.N. Galloni Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma Hum Mol Genet 18 24 2009 4818 4829
28. G.L. Hall, R.J. Shaw, E.A. Field, S.N. Rogers, D.N. Sutton, and J.A. Woolgar P16 Promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia Cancer Epidemiol Biomarkers Prev 17 8 2008 2174 2179