Sleep disturbance among spontaneously hypertensive rats is mediated by an α1-adrenergic mechanism

American Journal of Hypertension

Volumn 25, Issue 10, 2012, Pages 1110-1117

  Kuo, Terry B J ^a,b,c   Chen, Chun Yu ^a   Lai, Chun Ting ^a   Chuan, Tsai Yu ^a   Wu, Wen Yi ^a   Tsai, Shih Chih ^b   Yang, Cheryl C H ^a,b,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI CITY HOSPITAL   (Taiwan)

^c NATIONAL CENTRAL UNIVERSITY   (Taiwan)

Author keywords

adrenergic antagonist; adrenergic antagonist; blood pressure; hypertension; sleep; spontaneously hypertensive rat; sympathetic activity; telemetry

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ATENOLOL; BETA ADRENERGIC RECEPTOR; HYDRALAZINE; PHENTOLAMINE; PRAZOSIN; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE THERAPY; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE VARIABILITY; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; HEART RATE VARIABILITY; MALE; NONHUMAN; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RAT; SLEEP DISORDER; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC TONE; TELEMETRY;

ANIMALS; ATENOLOL; BLOOD PRESSURE; MALE; PRAZOSIN; PROPRANOLOL; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA-1; SLEEP; SLEEP DISORDERS;

EID: 84866354289     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1038/ajh.2012.93     Document Type: Article

References (50)

1. Egan BM. Sleep and hypertension: burning the candle at both ends really is hazardous to your health. Hypertension 2006; 47:816-817. (Pubitemid 44297546)
2. Calhoun DA, Harding SM. Sleep and hypertension. Chest 2010; 138:434-443.
3. Kim J, Jo I. Age-dependent association between sleep duration and hypertension in the adult Korean population. Am J Hypertens 2010; 23:1286-1291.
4. Fang J, Wheaton AG, Keenan NL, Greenlund KJ, Perry GS, Croft JB. Association of sleep duration and hypertension among US adults varies by age and sex. Am J Hypertens 2012; 25:335-341.
5. Alebiosu OC, Ogunsemi OO, Familoni OB, Adebayo PB, Ayodele OE. Quality of sleep among hypertensive patients in a semi-urban Nigerian community: a prospective study. Postgrad Med 2009; 121:166-172.
6. Houyez F, Degoulet P, Cittee J, Fouriaud C, Jacquinet-Salord MC, Lang T, Aimé F. [Sleep and hypertension. An epidemiologic study in 7,901 workers]. Arch Mal Coeur Vaiss 1990; 83:1085-1088. (Pubitemid 20225340)
7. Prejbisz A, Kabat M, Januszewicz A, Szelenberger W, Piotrowska AJ, Piotrowski W, Piwonski J, Makowiecka-Ciesla M, Widecka K, Patera B, Bieniaszewski L, Narkiewicz K, Tykarski A, Piejko A, Grodzicki T, Czerwienska B, Wiecek A. Characterization of insomnia in patients with essential hypertension. Blood Press 2006; 15:213-219.
8. Pedullà M, Silvestri R, Lasco A, Mento G, Lanuzza B, Sofia L, Frisina N. Sleep structure in essential hypertensive patients: differences between dippers and non-dippers. Blood Press 1995; 4:232-237.
9. Sherwood A, Routledge FS, Wohlgemuth WK, Hinderliter AL, Kuhn CM, Blumenthal JA. Blood pressure dipping: ethnicity, sleep quality, and sympathetic nervous system activity. Am J Hypertens 2011; 24:982-988.
10. Friedman O, Shukla Y, Logan AG. Relationship between self-reported sleep duration and changes in circadian blood pressure. Am J Hypertens 2009; 22:1205-1211.
11. Kuo TB, Shaw FZ, Lai CJ, Lai CW, Yang CC. Changes in sleep patterns in spontaneously hypertensive rats. Sleep 2004; 27:406-412. (Pubitemid 44138800)
12. Lake CR, Gullner HG, Polinsky RJ, Ebert MH, Ziegler MG, Bartter FC. Essential hypertension: central and peripheral norepinephrine. Science 1981; 211:955-957. (Pubitemid 11141463)
13. Grassi G, Seravalle G, Quarti-Trevano F. The 'neuroadrenergic hypothesis' in hypertension: current evidence. Exp Physiol 2010; 95:581-586.
14. Uchida T, Nishimura Y, Suzuki A. Age-related changes in cerebral and peripheral monoamine contents in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol Suppl 1995; 22:S80-S82. (Pubitemid 26062049)
15. Kasparov S, Teschemacher AG. Altered central catecholaminergic transmission and cardiovascular disease. Exp Physiol 2008; 93:725-740. (Pubitemid 351678598)
16. Howes LG, Rowe PR, Summers RJ, Louis WJ. Age related changes of catecholamines and their metabolites in central nervous system regions of spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats. Clin Exp Hypertens A 1984; 6:2263-2277. (Pubitemid 15116124)
17. Nakamura K, Nakamura K. Role of brainstem and spinal noradrenergic and adrenergic neurons in the development and maintenance of hypertension in spontaneously hypertensive rats. Naunyn Schmiedebergs Arch Pharmacol 1978; 305:127-133. (Pubitemid 9098915)
18. Mäkelä JP, Hilakivi IT. Effect of alpha-adrenoceptor blockade on sleep and wakefulness in the rat. Pharmacol Biochem Behav 1986; 24:613-616. (Pubitemid 16145201)
19. Kleinlogel H. Effects of the selective alpha 1-adrenoceptor blocker prazosin on EEG sleep and waking stages in the rat. Neuropsychobiology 1989; 21:100-103. (Pubitemid 20005891)
20. Pellejero T, Monti JM, Baglietto J, Jantos H, Pazos S, Cichevski V, Hawkins M. Effects of methoxamine and alpha-adrenoceptor antagonists, prazosin and yohimbine, on the sleep-wake cycle of the rat. Sleep 1984; 7:365-372. (Pubitemid 15223517)
21. Mendelson WB, Gillin JC, Dawson SD, Lewy AJ, Wyatt RJ. Effects of melatonin and propranolol on sleep of the rat. Brain Res 1980; 201:240-244. (Pubitemid 10015168)
22. Hilakivi I, Mäkelä J, Leppävuori A, Putkonen PT. Effects of two adrenergic betareceptor blockers on the sleep cycle of the cat. Med Biol 1978; 56:138-143. (Pubitemid 8373116)
23. Malliani A, Pagani M, Lombardi F, Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation 1991; 84:482-492.
24. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation 1996; 93:1043-1065.
25. Kuo TB, Yang CC. Sleep-related changes in cardiovascular neural regulation in spontaneously hypertensive rats. Circulation 2005; 112:849-854. (Pubitemid 41170071)
26. Kuo TB, Yang CC. Scatterplot analysis of EEG slow-wave magnitude and heart rate variability: an integrative exploration of cerebral cortical and autonomic functions. Sleep 2004; 27:648-656. (Pubitemid 38823361)
27. Ongini E, Milani S, Marzanatti M, Trampus M, Monopoli A. Effects of selected beta-adrenergic blocking agents on sleep stages in spontaneously hypertensive rats. J Pharmacol Exp Ther 1991; 257:114-119.
28. Russell V, Allie S, Wiggins T. Increased noradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder-the spontaneously hypertensive rat. Behav Brain Res 2000; 117:69-74.
29. Chen CY, Yang CC, Lin YY, Kuo TB. Locomotion-induced hippocampal theta is independent of visual information in rats during movement through a pipe. Behav Brain Res 2011; 216:699-704.
30. Li JY, Kuo TB, Hsieh SS, Yang CC. Changes in electroencephalogram and heart rate during treadmill exercise in the rat. Neurosci Lett 2008; 434:175-178.
31. Kuo TB, Yien HW, Hseu SS, Yang CC, Lin YY, Lee LC, Chan SH. Diminished vasomotor component of systemic arterial pressure signals and baroreflex in brain death. Am J Physiol 1997; 273:H1291-H1298.
32. Kuo TB, Lai CJ, Huang YT, Yang CC. Regression analysis between heart rate variability and baroreflex-related vagus nerve activity in rats. J Cardiovasc Electrophysiol 2005; 16:864-869. (Pubitemid 41623777)
33. Kuo TB, Lin T, Yang CC, Li CL, Chen CF, Chou P. Effect of aging on gender differences in neural control of heart rate. Am J Physiol 1999; 277:H2233-H2239. (Pubitemid 30048142)
34. Berne RM, Levy MN, Koeppen BM, Stanton BA. Physiology. Mosby, 2003, pp. 212-213.
35. Fewell JE, Johnson P. Acute increases in blood pressure cause arousal from sleep in lambs. Brain Res 1984; 311:259-265. (Pubitemid 14023377)
36. Horne RS, Berger PJ, Bowes G, Walker AM. Effect of sinoaortic denervation on arousal responses to hypotension in newborn lambs. Am J Physiol 1989; 256:H434-H440.
37. Ramos A, Mellerin Y, Mormède P, Chaouloff F. A genetic and multifactorial analysis of anxiety-related behaviours in Lewis and SHR intercrosses. Behav Brain Res 1998; 96:195-205. (Pubitemid 28494137)
38. Seidel WF, Maze M, Dement WC, Edgar DM. Alpha-2 adrenergic modulation of sleep: time-of-day-dependent pharmacodynamic profiles of dexmedetomidine and clonidine in the rat. J Pharmacol Exp Ther 1995; 275:263-273.
39. Kleinlogel H, Scholtysik G, Sayers AC. Effects of clonidine and BS 100-141 on the EEG sleep pattern in rats. Eur J Pharmacol 1975; 33:159-163.
40. Lanfumey L, Dugovic C, Adrien J. Beta 1 and beta 2 adrenergic receptors: their role in the regulation of paradoxical sleep in the rat. Electroencephalogr Clin Neurophysiol 1985; 60:558-567. (Pubitemid 15022814)
41. Saper CB, Scammell TE, Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005; 437:1257-1263. (Pubitemid 41568665)
42. Mitchell HA, Weinshenker D. Good night and good luck: norepinephrine in sleep pharmacology. Biochem Pharmacol 2010; 79:801-809.
43. De Sarro GB, Ascioti C, Froio F, Libri V, Nisticò G. Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1-and alpha 2-adrenoceptors affect sleep and arousal mechanisms. Br J Pharmacol 1987; 90:675-685. (Pubitemid 17099401)
44. Roach AG, Gomeni R, Mitchard M, Nicolas JP, Cavero I. The blood pressure lowering effects of intravenous versus intracerebroventricular prazosin in anaesthetised cats. Eur J Pharmacol 1978; 49:271-278. (Pubitemid 9201882)
45. Berridge CW. Neural substrates of psychostimulant-induced arousal. Neuropsychopharmacology 2006; 31:2332-2340. (Pubitemid 44607049)
46. Berridge CW. Noradrenergic modulation of arousal. Brain Res Rev 2008; 58:1-17.
47. Hernandez Peon R, Chavez Ibarra G, Aguilar Figueroa E. Somatic evoked potentials in one case of hysterical anaesthesia. Electroencephalogr Clin Neurophysiol 1963; 15:889-892.
48. Qualy JM, Westfall TC. Overflow of endogenous norepinephrine from PVH nucleus of DOCA-salt hypertensive rats. Am J Physiol 1995; 268:H1549-H1554.
49. Gangwisch JE, Heymsfield SB, Boden-Albala B, Buijs RM, Kreier F, Pickering TG, Rundle AG, Zammit GK, Malaspina D. Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination Survey. Hypertension 2006; 47:833-839. (Pubitemid 44297552)
50. Vgontzas AN, Liao D, Bixler EO, Chrousos GP, Vela-Bueno A. Insomnia with objective short sleep duration is associated with a high risk for hypertension. Sleep 2009; 32:491-497.