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Volumn 22, Issue 10, 2012, Pages 741-749

Genotypes of the MTHFR C677T and MTRR A66G genes act independently to reduce migraine disability in response to vitamin supplementation

Author keywords

gene; migraine; vitamin supplementation

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; METHIONINE SYNTHASE REDUCTASE; PLACEBO; PYRIDOXINE;

EID: 84866324187     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283576b6b     Document Type: Article
Times cited : (60)

References (38)
  • 1
    • 79958048554 scopus 로고    scopus 로고
    • A new horizon into the pathobiology, etiology and treatment of migraine
    • Dhillon KS, Singh J, Lyall JS. A new horizon into the pathobiology, etiology and treatment of migraine. Med Hypotheses 2011; 77:147-151.
    • (2011) Med Hypotheses , vol.77 , pp. 147-151
    • Dhillon, K.S.1    Singh, J.2    Lyall, J.S.3
  • 2
    • 70149101206 scopus 로고    scopus 로고
    • The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability
    • Lea R, Colson N, Quinlan S, Macmillan J, Griffiths L. The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability. Pharmacogenet Genomics 2009; 19:422-428.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 422-428
    • Lea, R.1    Colson, N.2    Quinlan, S.3    MacMillan, J.4    Griffiths, L.5
  • 3
    • 0035864635 scopus 로고    scopus 로고
    • Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction
    • DOI 10.1016/S0021-9150(00)00469-X, PII S002191500000469X
    • Chen J, Stampfer MJ, Ma J, Selhub J, Malinow MR, Hennekens CH, Hunter DJ. Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction. Atherosclerosis 2001; 154:667-672. (Pubitemid 32232164)
    • (2001) Atherosclerosis , vol.154 , Issue.3 , pp. 667-672
    • Chen, J.1    Stampfer, M.J.2    Ma, J.3    Selhub, J.4    Malinow M.Rene5    Hennekens, C.H.6    Hunter, D.J.7
  • 4
    • 0037302967 scopus 로고    scopus 로고
    • The neuronal versus vascular hypothesis of migraine and cortical spreading depression
    • DOI 10.1016/S1471-4892(02)00016-4, PII S1471489202000164
    • Parsons AA, Strijbos PJ. The neuronal versus vascular hypothesis of migraine and cortical spreading depression. Curr Opin Pharmacol 2003; 3:73-77. (Pubitemid 36131330)
    • (2003) Current Opinion in Pharmacology , vol.3 , Issue.1 , pp. 73-77
    • Parsons, A.A.1    Strijbos, P.J.L.M.2
  • 5
    • 0031441447 scopus 로고    scopus 로고
    • Microiontophoretic application of serotonin (5HT)(1B/1D) agonists inhibits trigeminal cell firing in the cat
    • DOI 10.1093/brain/120.12.2171
    • Storer RJ, Goadsby PJ. Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat. Brain 1997; 120 (Pt 12):2171-2177. (Pubitemid 28014593)
    • (1997) Brain , vol.120 , Issue.12 , pp. 2171-2177
    • Storer, R.J.1    Goadsby, P.J.2
  • 6
    • 4243070837 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura
    • Lea RA, Ovcaric M, Sundholm J, MacMillan J, Griffiths LR. The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura. BMC Med 2004; 2:3.
    • (2004) BMC Med , vol.2 , pp. 3
    • Lea, R.A.1    Ovcaric, M.2    Sundholm, J.3    MacMillan, J.4    Griffiths, L.R.5
  • 7
    • 0034785119 scopus 로고    scopus 로고
    • Polymorphisms of key enzymes in homocysteine metabolism affect diet responsiveness of plasma homocysteine in healthy women
    • Silaste ML, Rantala M, Sampi M, Alfthan G, Aro A, Kesaniemi YA. Polymorphisms of key enzymes in homocysteine metabolism affect diet responsiveness of plasma homocysteine in healthy women. J Nutr 2001; 131:2643-2647. (Pubitemid 32947789)
    • (2001) Journal of Nutrition , vol.131 , Issue.10 , pp. 2643-2647
    • Silaste, M.-L.1    Rantala, M.2    Sampi, M.3    Alfthan, G.4    Aro, A.5    Kesaniemi, Y.A.6
  • 8
    • 0031904465 scopus 로고    scopus 로고
    • Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)
    • DOI 10.1007/s003359900838
    • Goyette P, Pai A, Milos R, Frosst P, Tran P, Chen Z, et al. Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR). Mamm Genome 1998; 9:652-656. (Pubitemid 28355328)
    • (1998) Mammalian Genome , vol.9 , Issue.8 , pp. 652-656
    • Goyette, P.1    Pai, A.2    Milos, R.3    Frosst, P.4    Tran, P.5    Chen, Z.6    Chan, M.7    Rozen, R.8
  • 9
    • 0028487161 scopus 로고
    • Human methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
    • DOI 10.1038/ng0694-195
    • Goyette P, Sumner JS, Milos R, Duncan AM, Rosenblatt DS, Matthews RG, Rozen R. Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nat Genet 1994; 7: 195-200. (Pubitemid 24174661)
    • (1994) Nature Genetics , vol.7 , Issue.2 , pp. 195-200
    • Goyette, P.1    Sumner, J.S.2    Milos, R.3    Duncan, A.M.V.4    Rosenblatt, D.S.5    Matthews, R.G.6    Rozen, R.7
  • 11
    • 0347296358 scopus 로고    scopus 로고
    • Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk
    • DOI 10.1016/S0169-328X(02)00672-1
    • Kara I, Sazci A, Ergul E, Kaya G, Kilic G. Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk. Brain Res Mol Brain Res 2003; 111: 84-90. (Pubitemid 36332332)
    • (2003) Molecular Brain Research , vol.111 , Issue.1-2 , pp. 84-90
    • Kara, I.1    Sazci, A.2    Ergul, E.3    Kaya, G.4    Kilic, G.5
  • 12
    • 0034606262 scopus 로고    scopus 로고
    • The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine
    • Kowa H, Yasui K, Takeshima T, Urakami K, Sakai F, Nakashima K. The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine. Am J Med Genet 2000; 96: 762-764.
    • (2000) Am J Med Genet , vol.96 , pp. 762-764
    • Kowa, H.1    Yasui, K.2    Takeshima, T.3    Urakami, K.4    Sakai, F.5    Nakashima, K.6
  • 14
    • 36549042000 scopus 로고    scopus 로고
    • The 677 C/T MTHFR Polymorphism is Associated with Essential Hypertension, Coronary Artery Disease, and Higher Homocysteine Levels
    • DOI 10.1016/j.arcmed.2007.07.009, PII S0188440907003025
    • Ilhan N, Kucuksu M, Kaman D, Ilhan N, Ozbay Y. The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels. Arch Med Res 2008; 39: 125-130. (Pubitemid 350192019)
    • (2008) Archives of Medical Research , vol.39 , Issue.1 , pp. 125-130
    • Ilhan, N.1    Kucuksu, M.2    Kaman, D.3    Ilhan, N.4    Ozbay, Y.5
  • 15
    • 67650311784 scopus 로고    scopus 로고
    • Association of the C677T polymorphism in the MTHFR gene with migraine: A metaanalysis
    • Rubino E, Ferrero M, Rainero I, Binello E, Vaula G, Pinessi L. Association of the C677T polymorphism in the MTHFR gene with migraine: a metaanalysis. Cephalalgia 2009; 29:818-825.
    • (2009) Cephalalgia , vol.29 , pp. 818-825
    • Rubino, E.1    Ferrero, M.2    Rainero, I.3    Binello, E.4    Vaula, G.5    Pinessi, L.6
  • 17
    • 0034904708 scopus 로고    scopus 로고
    • The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations
    • DOI 10.1016/S0021-9150(00)00739-5, PII S0021915000007395
    • Gaughan DJ, Kluijtmans LA, Barbaux S, McMaster D, Young IS, Yarnell JW, et al. The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations. Atherosclerosis 2001; 157:451-456. (Pubitemid 32710025)
    • (2001) Atherosclerosis , vol.157 , Issue.2 , pp. 451-456
    • Gaughan, D.J.1    Kluijtmans, L.A.J.2    Barbaux, S.3    McMaster, D.4    Young, I.S.5    Yarnell, J.W.G.6    Evans, A.7    Whitehead, A.S.8
  • 20
    • 0033029228 scopus 로고    scopus 로고
    • Validity of an illness severity measure for headache in a population sample of migraine sufferers
    • DOI 10.1016/S0304-3959(98)00181-X, PII S030439599800181X
    • Stewart WF, Lipton RB, Simon D, Liberman J, Von Korff M. Validity of an illness severity measure for headache in a population sample of migraine sufferers. Pain 1999; 79:291-301. (Pubitemid 29076764)
    • (1999) Pain , vol.79 , Issue.2-3 , pp. 291-301
    • Stewart, W.F.1    Lipton, R.B.2    Simon, D.3    Liberman, J.4    Von Korff, M.5
  • 21
    • 0032902554 scopus 로고    scopus 로고
    • Reliability of the migraine disability assessment score in a population- based sample of headache sufferers
    • DOI 10.1046/j.1468-2982.1999.019002107.x
    • Stewart WF, Lipton RB, Kolodner K, Liberman J, Sawyer J. Reliability of the migraine disability assessment score in a population-based sample of headache sufferers. Cephalalgia 1999; 19:107-114, discussion 74. (Pubitemid 29170106)
    • (1999) Cephalalgia , vol.19 , Issue.2 , pp. 107-114
    • Stewart, W.F.1    Lipton, R.2    Kolodner, K.3    Liberman, J.4    Sawyer, J.5
  • 22
    • 30544454938 scopus 로고    scopus 로고
    • The global burden of migraine: Measuring disability in headache disorders with WHO's Classification of Functioning, Disability and Health (ICF)
    • DOI 10.1007/s10194-005-0252-4
    • Leonardi M, Steiner TJ, Scher AT, Lipton RB. The global burden of migraine: measuring disability in headache disorders with WHO's Classification of Functioning, Disability and Health (ICF). J Headache Pain 2005; 6: 429-440. (Pubitemid 43078769)
    • (2005) Journal of Headache and Pain , vol.6 , Issue.6 , pp. 429-440
    • Leonardi, M.1    Steiner, T.J.2    Scher, A.T.3    Lipton, R.B.4
  • 23
    • 79960121183 scopus 로고    scopus 로고
    • New frontiers in headache therapy
    • Rapoport A. New frontiers in headache therapy. Neurol Sci 2011; 32 (Suppl 1):S105-S109.
    • (2011) Neurol Sci , vol.32 , Issue.SUPPL. 1
    • Rapoport, A.1
  • 24
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002; 325:1202.
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 26
    • 0030903291 scopus 로고    scopus 로고
    • Association between migraine and stroke in a large-scale epidemiological study of the United States
    • Merikangas KR, Fenton BT, Cheng SH, Stolar MJ, Risch N. Association between migraine and stroke in a large-scale epidemiological study of the United States. Arch Neurol 1997; 54:362-368. (Pubitemid 27172854)
    • (1997) Archives of Neurology , vol.54 , Issue.4 , pp. 362-368
    • Merikangas, K.R.1    Fenton, B.T.2    Cheng, S.H.3    Stolar, M.J.4    Risch, N.5
  • 27
    • 0035933077 scopus 로고    scopus 로고
    • Association between migraine and endothelin type A receptor (ETA -231 A/G) gene polymorphism
    • Tzourio C, El Amrani M, Poirier O, Nicaud V, Bousser MG, Alperovitch A. Association between migraine and endothelin type A receptor (ETA-231A/G) gene polymorphism. Neurology 2001; 56:1273-1277. (Pubitemid 32455282)
    • (2001) Neurology , vol.56 , Issue.10 , pp. 1273-1277
    • Tzourio, C.1    El Amrani, M.2    Poirier, O.3    Nicaud, V.4    Bousser, M.-G.5    Alperovitch, A.6
  • 29
    • 0035655150 scopus 로고    scopus 로고
    • Shared mechanisms and comorbidities in neurologic and psychiatric disorders
    • Silberstein SD. Shared mechanisms and comorbidities in neurologic and psychiatric disorders. Headache 2001; 41 (Suppl 1):S11-S17.
    • (2001) Headache , vol.41 , Issue.SUPPL. 1
    • Silberstein, S.D.1
  • 32
    • 2242477014 scopus 로고    scopus 로고
    • Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials
    • Homocysteine Lowering Trialists Collaboration.
    • Homocysteine Lowering Trialists Collaboration. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. BMJ 1998; 316:894-898.
    • (1998) BMJ , vol.316 , pp. 894-898
  • 33
    • 27744603884 scopus 로고    scopus 로고
    • Dose-dependent effects of folic acid on blood concentrations of homocysteine: A meta-analysis of the randomized trials
    • Homocysteine Lowering Trialists Collaboration.
    • Homocysteine Lowering Trialists Collaboration. Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials. Am J Clin Nutr 2005; 82:806-812.
    • (2005) Am J Clin Nutr , vol.82 , pp. 806-812
  • 35
    • 0037069353 scopus 로고    scopus 로고
    • Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase
    • DOI 10.1021/bi020536s
    • Olteanu H, Munson T, Banerjee R. Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase. Biochemistry 2002; 41:13378-13385. (Pubitemid 35303896)
    • (2002) Biochemistry , vol.41 , Issue.45 , pp. 13378-13385
    • Olteanu, H.1    Munson, T.2    Banerjee, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.