Clues to Occult Cancer in Patients with Ischemic Stroke

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Kim, Suk Jae ^a   Park, Jae Hyun ^a   Lee, Mi Ji ^a   Park, Yun Gyoung ^a   Ahn, Myung Ju ^a   Bang, Oh Young ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; D DIMER;

ADULT; AGED; ARTICLE; BRAIN BLOOD VESSEL; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DISEASE ACTIVITY; DISEASE ASSOCIATION; FEMALE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; OCCULT CANCER; ONSET AGE; PROTEIN BLOOD LEVEL; STROKE PATIENT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; DIAGNOSIS, DIFFERENTIAL; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASMS; RETROSPECTIVE STUDIES; ROC CURVE; STROKE; YOUNG ADULT;

EID: 84866316312     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044959     Document Type: Article

References (25)

1. Graus F, Rogers LR, Posner JB, (1985) Cerebrovascular complications in patients with cancer. Medicine (Baltimore) 64: 16-35.
2. Bang OY, Seok JM, Kim SG, Hong JM, Kim HY, et al. (2011) Ischemic stroke and cancer: stroke severely impacts cancer patients, while cancer increases the number of strokes. J Clin Neurol 7: 53-59.
3. Seok JM, Kim SG, Kim JW, Chung CS, Kim GM, et al. (2010) Coagulopathy and embolic signal in cancer patients with ischemic stroke. Ann Neurol 68: 213-219.
4. Kim SG, Hong JM, Kim HY, Lee J, Chung PW, et al. (2010) Ischemic stroke in cancer patients with and without conventional mechanisms: a multicenter study in Korea. Stroke 41: 798-801.
5. Greenberg E, Divertie MB, Woolner LB, (1964) A Review of Unusual Systemic Manifestations Associated with Carcinoma. Am J Med 36: 106-120.
6. Monreal M, Lensing AW, Prins MH, Bonet M, Fernandez-Llamazares J, et al. (2004) Screening for occult cancer in patients with acute deep vein thrombosis or pulmonary embolism. J Thromb Haemost 2: 876-881.
7. Monreal M, Casals A, Boix J, Olazabal A, Montserrat E, et al. (1993) Occult cancer in patients with acute pulmonary embolism. A prospective study. Chest 103: 816-819.
8. Gore JM, Appelbaum JS, Greene HL, Dexter L, Dalen JE, (1982) Occult cancer in patients with acute pulmonary embolism. Ann Intern Med 96: 556-560.
9. Ay H, Furie KL, Singhal A, Smith WS, Sorensen AG, et al. (2005) An evidence-based causative classification system for acute ischemic stroke. Ann Neurol 58: 688-697.
10. Lee AY, Levine MN, Baker RI, Bowden C, Kakkar AK, et al. (2003) Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 349: 146-153.
11. Guercini F, Acciarresi M, Agnelli G, Paciaroni M, (2008) Cryptogenic stroke: time to determine aetiology. J Thromb Haemost 6: 549-554.
12. Kang DW, Chalela JA, Ezzeddine MA, Warach S, (2003) Association of ischemic lesion patterns on early diffusion-weighted imaging with TOAST stroke subtypes. Arch Neurol 60: 1730-1734.
13. Baird AE, Lovblad KO, Schlaug G, Edelman RR, Warach S, (2000) Multiple acute stroke syndrome: marker of embolic disease? Neurology 54: 674-678.
14. Hong CT, Tsai LK, Jeng JS, (2009) Patterns of acute cerebral infarcts in patients with active malignancy using diffusion-weighted imaging. Cerebrovasc Dis 28: 411-416.
15. Fujimoto S, Toyoda K, Jinnouchi J, Yasaka M, Kitazono T, et al. (2011) Differences in diffusion-weighted image and transesophageal echocardiographical findings in cardiogenic, paradoxical and aortogenic brain embolism. Cerebrovasc Dis 32: 148-154.
16. Grisold W, Oberndorfer S, Struhal W, (2009) Stroke and cancer: a review. Acta Neurol Scand 119: 1-16.
17. Kono T, Ohtsuki T, Hosomi N, Takeda I, Aoki S, et al. (2012) Cancer-associated ischemic stroke is associated with elevated d-dimer and fibrin degradation product levels in acute ischemic stroke with advanced cancer. Geriatr Gerontol Int 12: 468-474.
18. Tesselaar ME, Romijn FP, Van Der Linden IK, Prins FA, Bertina RM, et al. (2007) Microparticle-associated tissue factor activity: a link between cancer and thrombosis? J Thromb Haemost 5: 520-527.
19. Zwicker JI, Liebman HA, Neuberg D, Lacroix R, Bauer KA, et al. (2009) Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res 15: 6830-6840.
20. Prandoni P, Lensing AW, Buller HR, Cogo A, Prins MH, et al. (1992) Deep-vein thrombosis and the incidence of subsequent symptomatic cancer. N Engl J Med 327: 1128-1133.
21. Bura A, Cailleux N, Bienvenu B, Leger P, Bissery A, et al. (2004) Incidence and prognosis of cancer associated with bilateral venous thrombosis: a prospective study of 103 patients. J Thromb Haemost 2: 441-444.
22. Kwon HM, Kang BS, Yoon BW, (2007) Stroke as the first manifestation of concealed cancer. J Neurol Sci 258: 80-83.
23. Sorensen HT, Mellemkjaer L, Olsen JH, Baron JA, (2000) Prognosis of cancers associated with venous thromboembolism. N Engl J Med 343: 1846-1850.
24. Blom JW, Osanto S, Rosendaal FR, (2004) The risk of a venous thrombotic event in lung cancer patients: higher risk for adenocarcinoma than squamous cell carcinoma. J Thromb Haemost 2: 1760-1765.
25. Lee AY, Levine MN, (2003) Venous thromboembolism and cancer: risks and outcomes. Circulation 107: I17-21.