Stability indicating hptlc method for simultaneous determination of Valsartan and Hydrochlorothiazide In tablets

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 4, Issue SUPPL. 4, 2012, Pages 468-471

  Singh, Sunil ^a   Patel, Kuldeep ^b   Agrawal, Vipin Ku ^a   Chaturvedi, Shashank ^a  

^a Invertis Group of Institutions   (India)

^b NRI Institute of Pharmacy   (India)

Author keywords

HPTLC; Hydrochlorthiazide; Ramipril; Simultaneous estimation; Telmisartan; Validation; Valsartan

Indexed keywords

ACETIC ACID; ACETIC ACID ETHYL ESTER; ALUMINUM; AMLODIPINE PLUS HYDROCHLOROTHIAZIDE PLUS VALSARTAN; CHLOROFORM; UNCLASSIFIED DRUG; VALZAAR H;

ABSORPTION; ANALYTICAL EQUIPMENT; ARTICLE; DENSITOMETRY; DRUG DEGRADATION; DRUG DOSAGE FORM; DRUG HYDROLYSIS; DRUG OXIDATION; DRUG STABILITY; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PHOTOCATALYSIS; PHOTODEGRADATION; QUANTITATIVE ANALYSIS; TABLET FORMULATION; VALIDATION STUDY;

EID: 84866311712     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Budavari S, O'Neil MJ, Smith A, Heckelman PE Ed. The Merck Index. 13th edition, Division of Merck and Co., White house station: Merck Research Lab publisher; NJ, USA; 2001:148.
2. Chiolro A and Burnier M. Expert Opinion on investigational Drugs, 1998, 7: 1915.
3. Siddiqui N, Husain A, Chaudhry L, Alam MS, Mitra M, Bhasin PS Pharmacological and pharmaceutical profile of Valsartan. A review. J. Applied Pharm. Sci. 2011;1(4): 12-19.
4. Tian DF, Tian XL, TianT, Wang ZY, Mo FK Simultaneous determination of valsartan and hydrochlorothiazide in tablets by RP-HPLC. Indian J Pharm Sci. 2008;70(3):372-374.
5. Thanusha G, Babu CJG, Basavaraj KPC, Panditi VR, Sharadha C Validated RP-HPLC method for the quantitative estimation of valsartan in bulk and pharmaceutical dosage forms. Int. J. Chem. Tech Res. 2010;2(2):1194-8.
6. Varghese SJ, Ravi TK Quantitative simultaneous determination of amlodipine, valsartan, and hydrochlorothiazide in "exforge hct" tablets using high performance liquid chromatography and high performance thin-layer chromatography. J. Liq. Chromatogr. Rel. Technol. 2011;34(12):981-994.
7. Goyal A, Singhvi I Spectrophotometric estimation of ethamsylate and mefenamic acid from a binary mixture by dual wavelength and simultaneous equation methods. Indian J. Pharm. Sci. 2008;70(1):108-111.
8. Shukla R, Shivkumar R, Shivan KN Development of a UVspectrophotometric method for the simultaneous determination of tramadol hydrochloride and paracetamol in bulk and marketed product. Bull. Pharm. Res. 2011;1(1):62-66.
9. Anandakumar k, Jayamariappan M Absorption correction method for the simultaneous estimation of amlodipine besylate, Valsartan and hydrochlorothiazide in bulk and in combined tablet dosage form. Int J Pharm Pharm Sci. 2011;3(1):23-27.
10. Reddy R, Kumar P, Krishna A, Reddy V Wasimul Haque S. Stability indicating HPLC method for simultaneous estimation of low level impurities of Telmisartan and hydrochlorothiazide in tablet dosage form. Int J Pharm Pharm Sci. 2012;4(1):497-504.
11. International Conference on Harmonization, ICH Q1 A (R2); Stability Testing of New Drug Substances and Products 2003.
12. ICH/CPMP guidelines Q2A, Text on Validation of Analytical Procedures, 1994.
13. ICH/CPMP Guidelines Q2B, Validation of Analytical Procedures-Methodology, 1996.
14. US FDA, General principles of validation, Rockville, MD, Center for Drug Evaluation and Research (CDER), May 1987.