-
1
-
-
0037380873
-
A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system
-
Laur'en J, Airaksinen MS, Saarma M, Timmusk TT (2003) A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system. Genomics 81, 411-421.
-
(2003)
Genomics
, vol.81
, pp. 411-421
-
-
Laur'En, J.1
Airaksinen, M.S.2
Saarma, M.3
Timmusk, T.T.4
-
2
-
-
61549142067
-
An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers
-
Linhoff MW, Laur'en J, Cassidy RM, Dobie FA, Takahashi H, Nygaard HB, Airaksinen MS, Strittmatter SM, Craig AM (2009) An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers. Neuron 61, 734-749.
-
(2009)
Neuron
, vol.61
, pp. 734-749
-
-
Linhoff, M.W.1
Laur'En, J.2
Cassidy, R.M.3
Dobie, F.A.4
Takahashi, H.5
Nygaard, H.B.6
Airaksinen, M.S.7
Strittmatter, S.M.8
Craig, A.M.9
-
3
-
-
72449202226
-
LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation
-
de Wit J, Sylwestrak E, O'Sullivan ML, Otto S, Tiglio K, Savas JN, Yates JR 3rd, Comoletti D, Taylor P, Ghosh A (2009) LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation. Neuron 64, 799-806.
-
(2009)
Neuron
, vol.64
, pp. 799-806
-
-
De Wit, J.1
Sylwestrak, E.2
O'Sullivan, M.L.3
Otto, S.4
Tiglio, K.5
Savas, J.N.6
Yates III, J.R.7
Comoletti, D.8
Taylor, P.9
Ghosh, A.10
-
4
-
-
72149130256
-
LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation
-
Ko J, FuccilloMV,Malenka RC, Sudhof TC (2009) LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation. Neuron 64, 791-798.
-
(2009)
Neuron
, vol.64
, pp. 791-798
-
-
Ko, J.1
Fuccillo, M.V.2
Malenka, R.C.3
Sudhof, T.C.4
-
5
-
-
77953206739
-
LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development
-
Siddiqui TJ, Pancaroglu R, KangY, Rooyakkers A, CraigAM (2010) LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development. J Neurosci 30, 7495-7506.
-
(2010)
J Neurosci
, vol.30
, pp. 7495-7506
-
-
Siddiqui, T.J.1
Pancaroglu, R.2
Kang, Y.3
Rooyakkers, A.4
Craig, A.M.5
-
7
-
-
18244389436
-
The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease
-
Gandy S (2005) The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease. J Clin Invest 115, 1121-1129.
-
(2005)
J Clin Invest
, vol.115
, pp. 1121-1129
-
-
Gandy, S.1
-
8
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
Bertram L, Blacker D, Mullin K, Keeney D, Jones J, Basu S, Yhu S, McInnis MG, Go RC, Vekrellis K, Selkoe DJ, Saunders AJ, Tanzi RE (2000) Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290, 2302-2303.
-
(2000)
Science
, vol.290
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
-
9
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, Lillystone S, Kehoe P, Rudrasingham V, Jones L, Lovestone S, Perez-Tur J, Williams J, Owen MJ, Hardy J, Goate AM (2000) Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290, 2304-2305.
-
(2000)
Science
, vol.290
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshall, H.3
Kwon, J.4
Meyer, D.5
Ramic, D.6
Shears, S.7
Booth, J.8
Devrieze, F.W.9
Crook, R.10
Hamshere, M.11
Abraham, R.12
Tunstall, N.13
Rice, F.14
Carty, S.15
Lillystone, S.16
Kehoe, P.17
Rudrasingham, V.18
Jones, L.19
Lovestone, S.20
Perez-Tur, J.21
Williams, J.22
Owen, M.J.23
Hardy, J.24
Goate, A.M.25
more..
-
10
-
-
0034703979
-
Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG (2000) Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science 290, 2303-2304.
-
(2000)
Science
, vol.290
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
Eckman, C.4
Baker, M.5
Adamson, J.6
Ronald, J.7
Blangero, J.8
Hutton, M.9
Younkin, S.G.10
-
11
-
-
33845202373
-
LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for lateonset Alzheimer's disease
-
Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ (2006) LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for lateonset Alzheimer's disease. Proc Natl Acad Sci U S A 103, 17967-17972.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17967-17972
-
-
Majercak, J.1
Ray, W.J.2
Espeseth, A.3
Simon, A.4
Shi, X.P.5
Wolffe, C.6
Getty, K.7
Marine, S.8
Stec, E.9
Ferrer, M.10
Strulovici, B.11
Bartz, S.12
Gates, A.13
Xu, M.14
Huang, Q.15
Ma, L.16
Shughrue, P.17
Burchard, J.18
Colussi, D.19
Pietrak, B.20
Kahana, J.21
Beher, D.22
Rosahl, T.23
Shearman, M.24
Hazuda, D.25
Sachs, A.B.26
Koblan, K.S.27
Seabrook, G.R.28
Stone, D.J.29
more..
-
12
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: Evidence for augmentation of a 42-specific gamma secretase
-
Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, Copeland NG, Lee MK, Younkin LH, Wagner SL, Younkin SG, Borchelt DR (2004) Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: Evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 13, 159-170.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
Younkin, S.G.11
Borchelt, D.R.12
-
13
-
-
0033574625
-
Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system
-
Rodriguez I, Feinstein P, Mombaerts P (1999) Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system. Cell 97, 199-208.
-
(1999)
Cell
, vol.97
, pp. 199-208
-
-
Rodriguez, I.1
Feinstein, P.2
Mombaerts, P.3
-
14
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid beta protein in the Tg2576 transgenic mouse model of Alzheimer's disease
-
Kawarabayashi T, Younkin L, Saido T, Shoji M, Ashe K, Younkin S (2001) Age-dependent changes in brain, CSF, and plasma amyloid beta protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci 21, 372-381.
-
(2001)
J Neurosci
, vol.21
, pp. 372-381
-
-
Kawarabayashi, T.1
Younkin, L.2
Saido, T.3
Shoji, M.4
Ashe, K.5
Younkin, S.6
-
15
-
-
33750455150
-
Control of peripheral nerve myelination by the betasecretase BACE1
-
Willem M, Garratt AN, Novak B, Citron M, Kaufmann S, Rittger A, DeStrooper B, Saftig P, Birchmeier C, Haass C (2006) Control of peripheral nerve myelination by the betasecretase BACE1. Science 314, 664-666.
-
(2006)
Science
, vol.314
, pp. 664-666
-
-
Willem, M.1
Garratt, A.N.2
Novak, B.3
Citron, M.4
Kaufmann, S.5
Rittger, A.6
Destrooper, B.7
Saftig, P.8
Birchmeier, C.9
Haass, C.10
-
16
-
-
30444440132
-
BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions
-
Laird FM, Cai H, SavonenkoAV, Farah MH,HeK, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC (2005) BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. J Neurosci 25, 11693-11709.
-
(2005)
J Neurosci
, vol.25
, pp. 11693-11709
-
-
Laird, F.M.1
Cai, H.2
Farah Mhhek, S.3
Melnikova, T.4
Wen, H.5
Chiang, H.C.6
Xu, G.7
Koliatsos, V.E.8
Borchelt, D.R.9
Price, D.L.10
Lee, H.K.11
Wong, P.C.12
-
17
-
-
41549107577
-
The basic biology of BACE1: A key therapeutic target for Alzheimer's disease
-
Cole SL, Vassar R (2007) The basic biology of BACE1: a key therapeutic target for Alzheimer's disease. Curr Genomics 8, 509-530.
-
(2007)
Curr Genomics
, vol.8
, pp. 509-530
-
-
Cole, S.L.1
Vassar, R.2
-
18
-
-
34249745769
-
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
-
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Heward CB, Ravid R, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Kukull W, Papassotiropoulos A, Stephan DA (2007) GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron 54, 713-720.
-
(2007)
Neuron
, vol.54
, pp. 713-720
-
-
Reiman, E.M.1
Webster, J.A.2
Myers, A.J.3
Hardy, J.4
Dunckley, T.5
Zismann, V.L.6
Joshipura, K.D.7
Pearson, J.V.8
Hu-Lince, D.9
Huentelman, M.J.10
Craig, D.W.11
Coon, K.D.12
Liang, W.S.13
Herbert, R.H.14
Beach, T.15
Rohrer, K.C.16
Zhao, A.S.17
Leung, D.18
Bryden, L.19
Marlowe, L.20
Kaleem, M.21
Mastroeni, D.22
Grover, A.23
Heward, C.B.24
Ravid, R.25
Rogers, J.26
Hutton, M.L.27
Melquist, S.28
Petersen, R.C.29
Alexander, G.E.30
Caselli, R.J.31
Kukull, W.32
Papassotiropoulos, A.33
Stephan, D.A.34
more..
-
19
-
-
26944473203
-
Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease
-
Martin ER, Bronson PG, Li YJ, Wall N, Chung RH, Schmechel DE, Small G, Xu PT, Bartlett J, Schnetz-Boutaud N, Haines JL, Gilbert JR, Pericak-Vance MA (2005) Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. J Med Genet 42, 787-792.
-
(2005)
J Med Genet
, vol.42
, pp. 787-792
-
-
Martin, E.R.1
Bronson, P.G.2
Li, Y.J.3
Wall, N.4
Chung, R.H.5
Schmechel, D.E.6
Small, G.7
Xu, P.T.8
Bartlett, J.9
Schnetz-Boutaud, N.10
Haines, J.L.11
Gilbert, J.R.12
Pericak-Vance, M.A.13
-
20
-
-
38349038412
-
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
-
Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR, Briley JD, Borrie M, Coletta N, Delisle R, Dhalla D, Ehm MG, Feldman HH, Fornazzari L, Gauthier S, Goodgame N, Guzman D, Hammond S, Hollingworth P, Hsiung GY, Johnson J, Kelly DD, Keren R, Kertesz A, King KS, Lovestone S, Loy-English I, Matthews PM, Owen MJ, Plumpton M, Pryse-Phillips W, Prinjha RK, Richardson JC, Saunders A, Slater AJ, St George-Hyslop PH, Stinnett SW, Swartz JE, Taylor RL, Wherrett J, Williams J, Yarnall DP, Gibson RA, Irizarry MC, Middleton LT, Roses AD (2008) Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol 65, 45-53.
-
(2008)
Arch Neurol
, vol.65
, pp. 45-53
-
-
Li, H.1
Wetten, S.2
Li, L.3
St Jean, P.L.4
Upmanyu, R.5
Surh, L.6
Hosford, D.7
Barnes, M.R.8
Briley, J.D.9
Borrie, M.10
Coletta, N.11
Delisle, R.12
Dhalla, D.13
Ehm, M.G.14
Feldman, H.H.15
Fornazzari, L.16
Gauthier, S.17
Goodgame, N.18
Guzman, D.19
Hammond, S.20
Hollingworth, P.21
Hsiung, G.Y.22
Johnson, J.23
Kelly, D.D.24
Keren, R.25
Kertesz, A.26
King, K.S.27
Lovestone, S.28
Loy-English, I.29
Matthews, P.M.30
Owen, M.J.31
Plumpton, M.32
Pryse-Phillips, W.33
Prinjha, R.K.34
Richardson, J.C.35
Saunders, A.36
Slater, A.J.37
St George-Hyslop, P.H.38
Stinnett, S.W.39
Swartz, J.E.40
Taylor, R.L.41
Wherrett, J.42
Williams, J.43
Yarnall, D.P.44
Gibson, R.A.45
Irizarry, M.C.46
Middleton, L.T.47
Roses, A.D.48
more..
-
21
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE (2007) Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database. Nat Genet 39, 17-23.
-
(2007)
Nat Genet
, vol.39
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
|