Distinct Pattern of Immunophenotypic Features of Innate and Adaptive Immunity as a Putative Signature of Clinical and Laboratorial Status of Patients with Localized Cutaneous Leishmaniasis

Scandinavian Journal of Immunology

Volumn 76, Issue 4, 2012, Pages 421-432

  Freitas Teixeira, P M ^a   Silveira Lemos, D ^b,c   Giunchetti, R C ^b,c   Baratta Masini, A ^a   Mayrink, W ^c   Peruhype Magalhaes V ^a   Rocha, R D R ^a   Campi Azevedo, A C ^a   Teixeira Carvalho, A ^a   Martins Filho, O A ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; IMMUNOGLOBULIN G; NITRATE; NITROGEN DIOXIDE;

ADAPTIVE IMMUNITY; ADOLESCENT; ADULT; AGED; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; DISEASE DURATION; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOPHENOTYPING; INNATE IMMUNITY; LEISHMANIN SKIN TEST; LOCALIZED CUTANEOUS LEISHMANIASIS; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NEUTROPHIL COUNT; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SKIN LEISHMANIASIS;

ADAPTIVE IMMUNITY; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; B-LYMPHOCYTES; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; FEMALE; HLA-DR ANTIGENS; HUMANS; IMMUNITY, INNATE; IMMUNOPHENOTYPING; INFANT; LEISHMANIA BRAZILIENSIS; LEISHMANIASIS, CUTANEOUS; MALE; MIDDLE AGED; NEUTROPHILS; NITRATES; NITRITES; SKIN; T-LYMPHOCYTES;

EID: 84866280632     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2012.02748.x     Document Type: Article

References (58)

1. Basano AS, Camargo LMA. Leishmaniose tegumentar americana: histórico, epidemiologia e perspectivas de controle. Rev Bras Epidemiol 2004;7:1-10.
2. Baptista C, Schubach AO, Madeira MF et al. Leishmania (Viannia) braziliensis genotypes identified in lesions of patients with atypical or typical manifestations of tegumentary leishmaniasis: evaluation by two molecular markers. Exp Parasitol 2009;121:317-22.
3. Oliveira CC, Lacerda HG, Martins DRM et al. Changing epidemiology of American cutaneous leishmaniasis (ACL) in Brazil: a disease of the urban-rural interface. Acta Trop 2004;90:155-62.
4. Oliveira-Neto MP, Mattos MS, Perez MA et al. American tegumentary leishmaniasis (ATL) in Rio de Janeiro state, Brazil: main clinical and epidemiological characteristics. Int J Dermatol 2000;39:506-14.
5. Marsden PD. Personal experience with diagnostic and therapeutic aspects of human Leishmania (Viannia) braziliensis in Três Braços. Mem Inst Oswaldo Cruz 1994;89:485-7.
6. Passos VM, Barreto SM, Romanha AJ et al. Cutaneous leishmaniasis in the Metropolitan Region of Belo Horizonte: clinical, laboratory, therapeutic and prognostic features (1989-95). Rev Soc Bras Med Trop 2001;34:5-12.
7. Romero GA, Guerra MVF, Paes MG et al. Comparison of cutaneous leishmaniasis due to Leishmania (Viannia) braziliensis and L. (V.) guyanensis in Brazil: clinical findings and diagnostic approach. Clin Infect Dis 2001;32:1304-12.
8. Falqueto A, Sessa PA, Ferreira AL et al. Epidemiological and clinical features of Leishmania (Viannia) braziliensis American cutaneous and mucocutaneous leishmaniasis in the State of Espírito Santo, Brazil. Mem Inst Oswaldo Cruz 2003;98:1003-10.
9. Andrade MS, Brito MEF, Silva TS et al. American tegumentary leishmaniasis caused by Leishmania (Viannia) braziliensis in military training area of Zona da Mata in Pernambuco. Ver Soc Bras Med Trop 2005;38:229-33.
10. Boaventura VS, Café V, Costa J et al. Concomitant early mucosal and cutaneous leishmaniasis in Brazil. Am J Trop Med Hyg 2006;75:267-9.
11. Dorval MEMC, Oshiro ET, Cupollilo E et al. Occurrence of American tegumentary leishmaniasis in the Mato Grosso do Sul State associated to the infection for Leishmania (Leishmania) amazonensis. Rev Soc Bras Med Trop 2006;39:43-6.
12. + T cell immune responses of immunocompetent and immunocompromised (AIDS) patients with American tegumentary leishmaniasis. Mem Inst Oswaldo Cruz 1996;91:381-4.
13. Toledo VP, Mayrink W, Gollob KJ et al. Immunochemotherapy in American cutaneous leishmaniasis: immunological aspects before and after treatment. Mem Inst Oswaldo Cruz 2001;96:89-98.
14. + T cells associated with cure of human cutaneous leishmaniasis. Infect Immun 1994;62:2614-8.
15. Conceição-Silva F, Dórea RC, Pirmez C et al. Quantitative study of Leishmania braziliensis braziliensis reactive T cells in peripheral blood and in the lesions of patients with American mucocutaneous leishmaniasis. Clin Exp Immunol 1990;79:221-6.
16. Pirmez C, Cooper C, Paes-Oliveira M et al. Immunologic responsiveness in American cutaneous leishmaniasis lesions. J Immunol 1990;145:3100-4.
17. Ribeiro-de-Jesus A, Almeida RP, Lessa H et al. Cytokine profile and pathology in human leishmaniasis. Braz J Med Biol Res 1998;31:143-8.
18. Barral-Netto M, Brodskyn C, Carvalho EM et al. Human leishmaniasis/cytokines.bahia.br. Braz J Med Biol Res 1998;31:149-55.
19. Da-Cruz AM, Bertho AL, Oliveira-Neto MP et al. Flow cytometric analysis of cellular infiltrate from American tegumentary leishmaniasis lesions. Br J Dermatol 2005;153:537-43.
20. Barral A, Jesus AR, Almeida RP et al. Evaluation of T-cell subsets in the lesion infiltrates of human cutaneous and mucocutaneous leishmaniasis. Parasite Immunol 1987;9:487-97.
21. Lima HC, Vasconcelos AW, David JR et al. American cutaneous leishmaniasis: in situ characterization of the cellular immune response with time. Am J Trop Med Hyg 1994;50:743-7.
22. Diaz NL, Zerpa O, Ponce LV et al. Intermediate or chronic cutaneous leishmaniasis: leukocyte immunophenotypes and cytokine characterization of the lesion. Exp Dermatol 2002;11:34-41.
23. Vieira MG, Oliveira F, Arruda S et al. B-cell infiltration and frequency of cytokine producing cells differ between localized and disseminated human cutaneous leishmaniasis. Mem Inst Oswaldo Cruz 2002;97:979-83.
24. Amato VS, de Andrade HF, Duarte MI. Mucosal leishmaniasis: in situ characterization of the host inflammatory response, before and after treatment. Acta Trop 2003;85:39-49.
25. Ber Rahman S, Ul Bari A. Cellular immune host response in acute cutaneous leishmaniasis. J Coll Physicians Surg Pak 2005;15:463-6.
26. Rocha PN, Almeida RP, Bacellar O et al. Down-regulation of Th1 type of response in early human American cutaneous leishmaniasis J. Infect Dis 1999;180:1731-4.
27. Castes M, Agnelli A, Verde O et al. Characterization of the cellular immune response in American cutaneous leishmaniasis. Clin Immunol Immunopathol 1983;27:176-86.
28. Saravia NG, Valderrama L, Labrada M et al. The relationship of Leishmania braziliensis subspecies and immune response to disease expression in New World leishmaniasis. J Infect Dis 1989;159:725-35.
29. Da-Cruz AM, Bittar R, Mattos M et al. T-cell-mediated immune responses in patients with cutaneous or mucosal leishmaniasis: long-term evaluation after therapy. Clin Diagn Lab Immunol 2002;9:251-6.
30. Rocha RD, Gontijo CM, Santos SM et al. Performance analysis of the research of IgG antibodies alive promastigote anti-forms of Leishmania (V.) braziliensis (AAPV-IgG), for flow cytometry in the diagnosis of the leishmaniasis American tegumentar. Rev Soc Bras Med Trop 2003;2:15-8.
31. Camargo ME. Fluorescent antibody test for the serodiagnosis of American trypanosomiasis. Technical modification employing preserved culture forms of Trypanosoma cruzi in a slide test. Rev Inst Med Trop Sao Paulo 1966;8:227-35.
32. Gontijo CM, da Silva ES, de Fuccio MB et al. Epidemiological studies of an outbreak of cutaneous leishmaniasis in the Rio Jequitinhonha Valley, Minas Gerais, Brazil. Acta Trop 2002;81:143-50.
33. da Costa CA, de Toledo VP, Enaro O et al. Montenegro skin test-evaluation of the composition and stability of the antigen preparation. Mem Inst Oswaldo Cruz 1996;91:193-4.
34. Green LC, Wagner DA, Glogowski J et al. Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal Biochem 1982;126:131-8.
35. Carvalho EM, Johnson WD, Barreto E et al. Cell mediated immunity in American cutaneous and mucosal leishmaniasis. J Immunol 1985;135:4144-8.
36. Baratta-Masini A, Teixeira-Carvalho A, Malaquias LC, Mayrink W, Martins-Filho OA, Correa-Oliveira R. Mixed cytokine profile during active cutaneous leishmaniasis and in natural resistance. Front Biosci 2007;12:839-49.
37. Guarín N, Palma GI, Pirmez C, Valderrama L, Tovar R, Saravia NG. Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis. Biomédica 2006;26:38-48.
38. Ceyhan AM, Yildirim M, Basak PY, Akkaya VB, Erturan I. A case of erysipeloid cutaneous leishmaniasis: atypical and unusual clinical variant. Am J Trop Med Hyg 2008;78:406-8.
39. Gosselin EJ, Wardwell K, Rigby WF et al. Induction of MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-gamma and IL-3. J Immunol 1993;151:1482-90.
40. Fanger NA, Liu C, Guyre PM et al. Activation of human T cells by major histocompatibility complex class II expressing neutrophils: proliferation in the presence of superantigens, but not tetanus toxoid. Blood 1997;89:4128-35.
41. Fossati G, Moots RJ, Bucknall RC et al. Differential role of neutrophil Fc-gamma receptor IIIB (CD16) in phagocytosis, bacterial killing, and responses to immune complexes. Arthritis Rheum 2002;46:1351-61.
42. Write CD, Mülsch A, Busse R et al. Generation of nitric oxide by human neutrophils. Biochem Biophys Res Commun 1989;160:813-9.
43. Evans TJ, Buttery LD, Carpenter A et al. Cytokine treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc Natl Acad Sci USA 1996;93:9553-8.
44. Vella A, Bellavite P, Adami A et al. Expression of FCepsilonII/CD23 on human neutrophils isolated from rheumatoid arthritis patients. Inflammation 1999;23:471-9.
45. Dugas B, Mossalayi MD, Damais C, Kolb JP. Nitric oxide production by human monocytes: evidence for a role of CD23. Immunol Today 1995;16:574-80.
46. Mudde CG, Hansel TT, von Reusen FC, Osterhoff BF, Bruijnzeelkoomen CA. IgE: an immunoglobulin specialized in antigen capture? Immunol Today 1990;11:440-3.
47. Bonnefoy JY, Guillot O, Spits H, Blanchard D, Ishizaka K, Banchereau J. The low-affinity receptor for IgE (CD23) on B lymphocytes is spatially associated with HLA-DR antigens. J Exp Med 1988;167:57-72.
48. Pirmez C, Yamamura M, Uyemura K, Paes-Oliveira M, Conceição-Silva F, Modlin RL. Cytokine patterns in the pathogenesis of human leishmaniasis. J Clin Invest 1993;91:1390-5.
49. Mendonça SC, Souza WJ, Nunes MP et al. Indirect immunofluorescence test in New World leishmaniasis: serological and clinical relationship. Mem Inst Oswaldo Cruz 1988;83:347-55.
50. Al-Jaser MH. Treatment trends of cutaneous leishmaniasis in Saudi Arabia. Saudi Med J 2005;26:1220-4.
51. Filardy AA, Pires DR, Dos Reis GA. Macrophages and neutrophils cooperate in immune responses to Leishmania infection. Cell Mol Life Sci 2011;68:1863-70.
52. Venuprasad K, Parab P, Prasad DV et al. Immunobiology of CD28 expression on human neutrophils. I. CD28 regulates neutrophil migration by modulating CXCR-1 expression. Eur J Immunol 2001;31:1536-43.
53. Venuprasad K, Banerjee PP, Chattopadhyay S et al. Human neutrophil-expressed CD28 interacts with macrophage B7 to induce phosphatidylinositol 3-kinase-dependent IFN-gamma secretion and restriction of Leishmania growth. J Immunol 2002;169:920-8.
54. Peters NC, Egen JG, Secundino N et al. In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies. Science 2008;321:970-4.
55. John B, Hunter CA. Neutrophil soldiers or Trojan horses? Science 2008;321:917-8.
56. Silveira FT, Lainson R, De Castro Gomes CM, Laurenti MD, Corbett CE. Immunopathogenic competences of Leishmania (V.) braziliensis and L. (L.) amazonensis in American cutaneous leishmaniasis. Parasite Immunol 2009;1:423-31.
57. Mossalayi MD, Vouldoukis I, Mamani-Matsuda M et al. CD23 mediates antimycobacterial activity of human macrophages. Infect Immun 2009;77:5537-42.
58. Vouldoukis I, Riveros-Moreno V, Dugas B et al. The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen. Proc Natl Acad Sci USA 1995;92:7804-8.