Escape from adaptive conflict follows from weak functional trade-offs and mutational robustness

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 37, 2012, Pages 14888-14893

  Sikosek, Tobias ^a   Chan, HueSun ^b   Bornberg Bauer, Erich ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Evolvability; Neutral network; Protein stability

Indexed keywords

PROTEIN;

ARTICLE; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; GENE DOSAGE; GENE DUPLICATION; GENETIC VARIABILITY; MOLECULAR EVOLUTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE;

ADAPTATION, BIOLOGICAL; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; GENE DUPLICATION; GENETIC FITNESS; MODELS, BIOLOGICAL; MUTATION; PROTEINS; SELECTION, GENETIC;

EID: 84866267075     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115620109     Document Type: Article

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