An evaluation of barrier repair foam on the molecular concentration profiles of intrinsic skin constituents utilizing confocal raman spectroscopy

Journal of Clinical and Aesthetic Dermatology

Volumn 5, Issue 8, 2012, Pages 14-17

  Cash, Kimberly ^b   High, Whitney ^a   De Sterke, Johanna ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; DODECYL SULFATE SODIUM; HYALURONIC ACID; HYLATOPICPLUS; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; FOAM; HUMAN; HUMAN EXPERIMENT; HYDRATION; IN VIVO STUDY; RAMAN SPECTROMETRY; SKIN DEFECT; STRATUM CORNEUM;

EID: 84866248032     PISSN: 19412789     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Del Rosso JQ, Levin J. The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin. J Clin Aesthet Dermatol. 2011;4(9):22-42.
2. Chilcott RP, Dalton CH, Emmanuel AJ, Allen CE, Bradley ST. Transepidermal water loss does not correlate with skin barrier function in vitro. J Invest Dermatol. 2002;118(5):871-875. doi: 10.1046/j.1523-1747.2002.01760.x. (Pubitemid 34526552)
3. Caspers PJ, Lucassen GW, Carter EA, Bruining HA, Puppels GJ. In vivo confocal Raman microspectroscopy of the skin: noninvasive determination of molecular concentration profiles. J Invest Dermatol. 2001;116(3):434-442. doi: 10.1046/j.1523-1747.2001.01258.x. (Pubitemid 32202909)
4. Elias P, Ahn S, Brown B, Crumrine D, Feingold KR. Origin of the epidermal calcium gradient: regulation by barrier status and role of active vs. passive mechanisms. J Invest Dermatol. 2002;119(6):1269-1274. (Pubitemid 36005608)
5. Trumbore M, Gurge R. A hyaluronic acid-ceramide based prescription emollient foam provides significant improvement of skin barrier function and skin hydration. Poster presented at Fall Clinical Dermatology Meeting. October 2010; Las Vegas, Nevada.
6. Frankel A, Sohn A, Patel RV, Lebwohl, M. Bilateral comparison study of pimecrolimus cream 1% and a ceramide-hyaluronic acid emollient foam in the treatment of patients with atopic dermatitis. J Drugs Dermatol. 2011;10(6):666-672.
7. Park KY, Kim DH, Jeong MS, Li K, Seo SJ. Changes of antimicrobial peptides and transepidermal water loss after topical application of tacrolimus and ceramide-dominant emollient in patients with atopic dermatitis. J Korean Med Sci. 2010;25(5):766-771. doi: 10.3346/jkms.2010.25.5.766.