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Volumn 3, Issue 3, 2012, Pages 130-135

Strengthening of antioxidant defense by Azadirachta indica in alloxan-diabetic rat tissues

Author keywords

Azadirachta indica; glutathione peroxidase; oxidative stress; superoxide dismutase

Indexed keywords

AZADIRACHTA INDICA EXTRACT; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INSULIN; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

EID: 84866241546     PISSN: 09759476     EISSN: 09762809     Source Type: Journal    
DOI: 10.4103/0975-9476.100174     Document Type: Article
Times cited : (30)

References (34)
  • 1
    • 0036325318 scopus 로고    scopus 로고
    • Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: Effect of vanadate and fenugreek (Trigonella foenum graecum)
    • DOI 10.1023/A:1016103131408
    • Genet S, Kale RK, Baquer NZ. Alteration in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: Effect of vanadate and fenugreek (Trigonella foenum graecum). Mol Cell Biochem 2002;236:7-12. (Pubitemid 34851222)
    • (2002) Molecular and Cellular Biochemistry , vol.236 , Issue.1-2 , pp. 7-12
    • Genet, S.1    Kale, R.K.2    Baquer, N.Z.3
  • 2
    • 0030048496 scopus 로고    scopus 로고
    • Oxidative stress and diabetic vascular complications
    • Giugliana D, Ceriello A, Paolisso G. Oxidative stress and diabetic vascular complications. Diabetes Care 1996;19:257-67. (Pubitemid 26070354)
    • (1996) Diabetes Care , vol.19 , Issue.3 , pp. 257-267
    • Giugliano, D.1    Ceriello, A.2    Paolisso, G.3
  • 3
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications of diabetes
    • Baynes JW. Role of oxidative stress in development of complications of diabetes. Diabetes 1991;40:405-12.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 4
    • 0020427486 scopus 로고
    • Biology of disease. Free radicals and tissue injury
    • Freeman BA, Crapo JD. Biology of diseases free radicals and injury. Lab Invest 1982;47:412-26. (Pubitemid 13229679)
    • (1982) Laboratory Investigation , vol.47 , Issue.5 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 5
    • 0023576328 scopus 로고
    • Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment
    • Wohaieb SA, Godin DV. Alterations in free radicals tissue defence mechanisms in streptozotocin-induced diabetes in rats: Effects of insulin treatment. Diabetes 1987;36:1014-8. (Pubitemid 18088387)
    • (1987) Diabetes , vol.36 , Issue.9 , pp. 1014-1018
    • Wohaieb, S.A.1    Godin, D.V.2
  • 6
    • 0025096104 scopus 로고
    • Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose
    • Hunt JV, Smith CT, Wolff SP. Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modifi cation by glucose. Diabetes 1990;39:1420-4. (Pubitemid 20372232)
    • (1990) Diabetes , vol.39 , Issue.11 , pp. 1420-1424
    • Hunt, J.V.1    Smith, C.C.T.2    Wolff, S.P.3
  • 7
    • 0026562860 scopus 로고
    • New insights on non-enzymatic glycosylation may lead to therapeutic approaches for the prevention of diabetic complications
    • Ceriello A, Quatraro A, Giugliano D. New insights on non-enzymatic glycosylation may lead to therapeutic approaches for the prevention of diabetic complications. Diabet Med 1992;9:297-9.
    • (1992) Diabet Med , vol.9 , pp. 297-299
    • Ceriello, A.1    Quatraro, A.2    Giugliano, D.3
  • 8
    • 0027428582 scopus 로고
    • The role of antioxidative treatment in diabetes mellitus
    • Packer L. The role of antioxidative treatment in diabetes mellitus. Diabetologia 1993;36:1212-3.
    • (1993) Diabetologia , vol.36 , pp. 1212-1213
    • Packer, L.1
  • 12
    • 0025113742 scopus 로고
    • Biochemical studies on hypoglycemic agents (1) Effect of Azadirachta indica leaf extract
    • El-Hawary ZM, Kholeif TS. Biochemical studies on hypoglycemic agents (1) Effect of Azadirachta indica leaf extract. Arch Phytother Res 1990;13:108-12.
    • (1990) Arch Phytother Res , vol.13 , pp. 108-112
    • El-Hawary, Z.M.1    Kholeif, T.S.2
  • 13
    • 0032888354 scopus 로고
    • Possible mechanism of antihyperglycemic effect of Azadirachta Indica leaf extract
    • Chattopadhyaya RR. Possible mechanism of antihyperglycemic effect of Azadirachta Indica leaf extract. J Ethnopharmacol 1990;67:373-6.
    • (1990) J Ethnopharmacol , vol.67 , pp. 373-376
    • Chattopadhyaya, R.R.1
  • 14
    • 0002575615 scopus 로고
    • Glucose over and under utilization in diabetes: Comparative studies on changes in activities of enzymes of glucose metabolism in rat kidney and liver
    • Sochor M, Baquer NZ, Mclean P. Glucose over and under utilization in diabetes: Comparative studies on changes in activities of enzymes of glucose metabolism in rat kidney and liver. Mol Physiol 1985;7:51-68.
    • (1985) Mol Physiol , vol.7 , pp. 51-68
    • Sochor, M.1    Baquer, N.Z.2    McLean, P.3
  • 15
    • 84874531668 scopus 로고    scopus 로고
    • Long term effect of Azadirachta indica on hyperglycemia, associated hyperlipidemia and tissue glycogen content in alloxan induced diabetic rats
    • Shailey S, Basir SF. Long term effect of Azadirachta indica on hyperglycemia, associated hyperlipidemia and tissue glycogen content in alloxan induced diabetic rats. J Pharm Res 2011;4:3.
    • (2011) J Pharm Res , vol.4 , pp. 3
    • Shailey, S.1    Basir, S.F.2
  • 16
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Maklund S, Maklund G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Bichem 1974;47:469-74.
    • (1974) Eur J Bichem , vol.47 , pp. 469-474
    • Maklund, S.1    Maklund, G.2
  • 18
    • 0017067418 scopus 로고
    • Gutathione peroxidase activity in selenium defi cient rat liver
    • Lawrence RA, Burk RF. Gutathione peroxidase activity in selenium defi cient rat liver. Biochem Biophys Res Commun 1976;71:1161-5.
    • (1976) Biochem Biophys Res Commun , vol.71 , pp. 1161-1165
    • Lawrence, R.A.1    Burk, R.F.2
  • 19
    • 0021276559 scopus 로고
    • Changes of reduced glutathion, glutathion reductase, and glutathione peroxidase after radiation in guinea pigs
    • Erden M, Bor NM. Changes in reduced glutathione, glutathione reductase and glutathione peroxidase after radiation in guinea pigs. Biochem Med 1984;31:217-27. (Pubitemid 14133780)
    • (1984) Biochemical Medicine , vol.31 , Issue.2 , pp. 217-227
    • Erden, M.1    Bor, N.M.2
  • 20
    • 0016411064 scopus 로고
    • Glucose-6-phosphate dehydrogenase from human erythrocytes
    • Colowick SP, Kaplan NO, editors New York: Academic Press
    • Cohen P, Rosemeyer MA. Glucose-6-phosphate dehydrogenase from human erythrocytes. In: Colowick SP, Kaplan NO, editors. Methods in Enzymology. Vol. 41. New York: Academic Press; 1975. p. 208-16.
    • (1975) Methods in Enzymology , vol.41 , pp. 208-216
    • Cohen, P.1    Rosemeyer, M.A.2
  • 21
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 23
    • 0028068186 scopus 로고
    • Free radicals, antioxidants and human diseases: Cause or consequence?
    • Halliwel B. Free radicals, antioxidants and human diseases: Cause or consequence? Lancet 1994;344:721-4.
    • (1994) Lancet , vol.344 , pp. 721-724
    • Halliwel, B.1
  • 24
    • 0037219409 scopus 로고    scopus 로고
    • Are oxidative stress - Activated signaling pathways mediators of insulin resistance and β-cell dysfunction?
    • DOI 10.2337/diabetes.52.1.1
    • Evans JL, Goldfi ne ID, Maddux BA, Grodsky GM. Are oxidative stress mediated signaling pathways mediators of insulin resistance and beta-cell dysfunction? Diabetes 2003;52:1-8. (Pubitemid 36042100)
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 1-8
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 25
    • 0033994409 scopus 로고    scopus 로고
    • Radicals and oxidative stress in diabetes
    • DOI 10.1046/j.1464-5491.2000.00259.x
    • West IC. Radicals and oxidative stress in diabetes. Diabet Med 2000;17:171-80. (Pubitemid 30212288)
    • (2000) Diabetic Medicine , vol.17 , Issue.3 , pp. 171-180
    • West, I.C.1
  • 26
    • 0029831258 scopus 로고    scopus 로고
    • Alterations in tissue glutathione antioxidant system in streptozotocin-induced diabetic rats
    • Mak DH, Ip SP, Li PC, Poon MK, Ko KM. Alterations in tissue glutathione antioxidant system in streptozotocin-induced diabetic rats. Mol Cell Biochem 1996;162:153-8. (Pubitemid 26394685)
    • (1996) Molecular and Cellular Biochemistry , vol.162 , Issue.2 , pp. 153-158
    • Mak, D.H.F.1    Ip, S.P.2    Li, P.C.3    Poon, M.K.T.4    Ko, K.M.5
  • 27
    • 0037104655 scopus 로고    scopus 로고
    • Kinetic studies on the hydrogen peroxide elimination by cultured PC12 cells: Rate limitation by glucose-6-phosphate dehydrogenase
    • DOI 10.1016/S0304-4165(02)00282-9, PII S0304416502002829
    • Hashida K, Sakakura Y, Makino N. Kinetic studies on the hydrogen peroxide elimination by cultured PC12 cells: Rate limitation by glucose-6-phosphate dehydrogenase. Biochim Biophys Acta 2002;1572:85-90. (Pubitemid 35223059)
    • (2002) Biochimica et Biophysica Acta - General Subjects , vol.1572 , Issue.1 , pp. 85-90
    • Hashida, K.1    Sakakura, Y.2    Makino, N.3
  • 28
    • 0037342685 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide
    • DOI 10.1161/01.ATV.0000056744.26901.BA
    • Leopold JA, Zhang YY, Scribner AW, Stanton RC, Loscalzo J. Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide. Arteriosceler Thromb Vasc Biol 2003;23:411-7. (Pubitemid 36337216)
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , Issue.3 , pp. 411-417
    • Leopold, J.A.1    Zhang, Y.-Y.2    Scribner, A.W.3    Stanton, R.C.4    Loscalzo, J.5
  • 29
    • 0037438878 scopus 로고    scopus 로고
    • a encoding glucose 6-phosphate dehydrogenase
    • DOI 10.1016/S0891-5849(02)01243-1, PII S0891584902012431
    • Felix K, Rockwood CD, Pretsch W, Bornkamm GW, Janz S. Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose-6-phosphate dehydrogenase. Free Radic Biol Med 2003;34:226-32. (Pubitemid 36090122)
    • (2003) Free Radical Biology and Medicine , vol.34 , Issue.2 , pp. 226-232
    • Felix, K.1    Rockwood, L.D.2    Pretsch, W.3    Bornkamm, G.-W.4    Janz, S.5
  • 30
    • 1942453606 scopus 로고    scopus 로고
    • The pentose phosphate pathway and other pathway of hexose metabolism
    • Murray RK, Granner DK, Mayes VW, editors USA: McGraw-Hill
    • Mayes PA. The pentose phosphate pathway and other pathway of hexose metabolism. In: Murray RK, Granner DK, Mayes VW, editors. Herper's Biochemistry. USA: McGraw-Hill; 2000. p. 219-37.
    • (2000) Herper's Biochemistry , pp. 219-237
    • Mayes, P.A.1
  • 31
    • 0033765672 scopus 로고    scopus 로고
    • High glucose level and free fatty acids stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
    • Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, et al. High glucose level and free fatty acids stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 2000;49:1939-45.
    • (2000) Diabetes , vol.49 , pp. 1939-1945
    • Inoguchi, T.1    Li, P.2    Umeda, F.3    Yu, H.Y.4    Kakimoto, M.5    Imamura, M.6
  • 32
    • 0028858064 scopus 로고
    • Lipid peroxidation and activity of antioxidant enzymes in diabetic rats
    • Kakkar R, Kalra J, Mantha SV, Prasad K. Lipid peroxidation and activity of antioxidant enzymes in diabetic rats. Mol Cell Biochem 1995;151:113-9.
    • (1995) Mol Cell Biochem , vol.151 , pp. 113-119
    • Kakkar, R.1    Kalra, J.2    Mantha, S.V.3    Prasad, K.4
  • 33
    • 1542709593 scopus 로고    scopus 로고
    • Lower doses of vanadate in combination with trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats
    • DOI 10.1016/j.cccn.2003.12.005, PII S0009898103005746
    • Mohamad S, Taha A, Bamezai RN, Basir SF, Baquer NZ. Lower doses of vanadate in combination with Trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats. Clin Chim Acta 2004;342:105-14. (Pubitemid 38352919)
    • (2004) Clinica Chimica Acta , vol.342 , Issue.1-2 , pp. 105-114
    • Mohamad, S.1    Taha, A.2    Bamezai, R.N.K.3    Basir, S.F.4    Baquer, N.Z.5


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