메뉴 건너뛰기




Volumn 24, Issue 4, 2012, Pages 221-225

Extreme hypothyroidism associated with sunitinib treatment for metastatic renal cancer

Author keywords

Extreme hypothyroidism; Sunitinib; Symptoms

Indexed keywords

BEVACIZUMAB; FUMARATE HYDRATASE; HEMOGLOBIN; LEVOTHYROXINE; SUNITINIB; THYROTROPIN; TREBANANIB;

EID: 84866240086     PISSN: 1120009X     EISSN: 19739478     Source Type: Journal    
DOI: 10.1179/1973947812Y.0000000022     Document Type: Article
Times cited : (11)

References (34)
  • 1
    • 78249244171 scopus 로고    scopus 로고
    • Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia
    • Kim TD, Schwarz M, Nogai H, Grille P, Westermann J, Plockinger U, et al. Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia. Thyroid. 2010; 11:1209-14.
    • (2010) Thyroid , vol.11 , pp. 1209-1214
    • Kim, T.D.1    Schwarz, M.2    Nogai, H.3    Grille, P.4    Westermann, J.5    Plockinger, U.6
  • 2
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
    • Sternberg CN, Davis ID, Mardiak J. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol. 2010;28(6):1061-8.
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3
  • 3
    • 77956290435 scopus 로고    scopus 로고
    • Abnormalities of thyroid function in Japanese patients with metastatic renal cell carcinoma treated with sorafenib: A prospective evaluation
    • Miyake H, Kurahashi T, Yamanaka K, Kondo Y, Muramaki M, Takenaka A, et al. Abnormalities of thyroid function in Japanese patients with metastatic renal cell carcinoma treated with sorafenib: a prospective evaluation. Urol Oncol. 2010;5:515-9.
    • (2010) Urol Oncol , vol.5 , pp. 515-519
    • Miyake, H.1    Kurahashi, T.2    Yamanaka, K.3    Kondo, Y.4    Muramaki, M.5    Takenaka, A.6
  • 4
    • 78751579135 scopus 로고    scopus 로고
    • The incidence and mechanism of sunitinib-induced thyroid atrophy in patients with metastatic renal cell carcinoma
    • Shinohara N, Takahashi M, Kamishima T, Ikushima H, Otsuka N, Ishizu A, et al. The incidence and mechanism of sunitinib-induced thyroid atrophy in patients with metastatic renal cell carcinoma. Br J Cancer. 2011;104:241-7.
    • (2011) Br J Cancer , vol.104 , pp. 241-247
    • Shinohara, N.1    Takahashi, M.2    Kamishima, T.3    Ikushima, H.4    Otsuka, N.5    Ishizu, A.6
  • 5
    • 77649291310 scopus 로고    scopus 로고
    • Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: A potential marker of irreversible thyroid dysfunction?
    • Rogiers A, Wolter P, de Beeck K, Thijs M, Decallonne B, Schoffski P. Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: a potential marker of irreversible thyroid dysfunction? Thyroid. 2010;20:317-22.
    • (2010) Thyroid , vol.20 , pp. 317-322
    • Rogiers, A.1    Wolter, P.2    de Beeck, K.3    Thijs, M.4    Decallonne, B.5    Schoffski, P.6
  • 6
    • 67650357388 scopus 로고    scopus 로고
    • Is hypothyroidism a clinically relevant toxicity of tyrosine kinase inhibitors?
    • Torino F, Corsello SM, Longo R, Barnabei A, Gasparini G. Is hypothyroidism a clinically relevant toxicity of tyrosine kinase inhibitors? Thyroid. 2009;19:539-40.
    • (2009) Thyroid , vol.19 , pp. 539-540
    • Torino, F.1    Corsello, S.M.2    Longo, R.3    Barnabei, A.4    Gasparini, G.5
  • 7
    • 77649310826 scopus 로고    scopus 로고
    • Sunitinib induces hypothyroidism with a markedly reduced vascularity
    • Makita N, Miyakawa M, Fujita T, Iiri T. Sunitinib induces hypothyroidism with a markedly reduced vascularity. Thyroid. 2010;20:323-6.
    • (2010) Thyroid , vol.20 , pp. 323-326
    • Makita, N.1    Miyakawa, M.2    Fujita, T.3    Iiri, T.4
  • 8
    • 34548764576 scopus 로고    scopus 로고
    • A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake
    • Mannavola D, Coco P, Vannucchi G, Bertuelli R, Carletto M, Casali PG, et al. A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. J Clin Endocrinol Metab. 2007;92:3531-4.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3531-3534
    • Mannavola, D.1    Coco, P.2    Vannucchi, G.3    Bertuelli, R.4    Carletto, M.5    Casali, P.G.6
  • 9
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol. 1999;17(8):2530-40.
    • (1999) J Clin Oncol , vol.17 , Issue.8 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3    Berg, W.4    Amsterdam, A.5    Ferrara, J.6
  • 10
    • 79958108040 scopus 로고    scopus 로고
    • Hereditary leiomyomatosis and renal cell cancer: Update on clinical and molecular characteristics
    • Lehtonen HJ. Hereditary leiomyomatosis and renal cell cancer: update on clinical and molecular characteristics. Fam Cancer. 2011;10(2):397-411.
    • (2011) Fam Cancer , vol.10 , Issue.2 , pp. 397-411
    • Lehtonen, H.J.1
  • 11
    • 70249114453 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors
    • Herbst RS, Hong D, Chap L, Kurzrock R, Jackson E, Silverman JM, et al. Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors. J Clin Oncol. 2009;27:3557-65.
    • (2009) J Clin Oncol , vol.27 , pp. 3557-3565
    • Herbst, R.S.1    Hong, D.2    Chap, L.3    Kurzrock, R.4    Jackson, E.5    Silverman, J.M.6
  • 13
    • 67650173972 scopus 로고    scopus 로고
    • Hypothyroidism related to tyrosine kinase inhibitors: An emerging toxic effect of targeted therapy
    • Torino F, Corsello SM, Longo R, Barnabei A, Gasparini G. Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. Nat Rev Clin Oncol. 2009;6:219-28.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 219-228
    • Torino, F.1    Corsello, S.M.2    Longo, R.3    Barnabei, A.4    Gasparini, G.5
  • 14
    • 84855999342 scopus 로고    scopus 로고
    • Severe clinical toxicities are correlated with survival in patients with advanced renal cell carcinoma treated with sunitinib and sorafenib
    • Di Fiore F, Rigal O, Ménager C, Michel P, Pfister C. Severe clinical toxicities are correlated with survival in patients with advanced renal cell carcinoma treated with sunitinib and sorafenib. Br J Cancer. 2011;105(12):1811-3.
    • (2011) Br J Cancer , vol.105 , Issue.12 , pp. 1811-1813
    • Di Fiore, F.1    Rigal, O.2    Ménager, C.3    Michel, P.4    Pfister, C.5
  • 15
    • 48349122489 scopus 로고    scopus 로고
    • The clinical implications of sunitinib-induced hypothyroidism: A prospective evaluation
    • Wolter P, Stefan C, Decallonne B, Dumez H, Bex M, Carmeliet P, et al. The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. Br J Cancer. 2008;99:448-54.
    • (2008) Br J Cancer , vol.99 , pp. 448-454
    • Wolter, P.1    Stefan, C.2    Decallonne, B.3    Dumez, H.4    Bex, M.5    Carmeliet, P.6
  • 16
    • 33750961647 scopus 로고    scopus 로고
    • Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors
    • Desai J, Yassa L, Marqusee E, George S, Frates MC, Chen MH, et al. Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Ann Intern Med. 2006;145:660-4.
    • (2006) Ann Intern Med , vol.145 , pp. 660-664
    • Desai, J.1    Yassa, L.2    Marqusee, E.3    George, S.4    Frates, M.C.5    Chen, M.H.6
  • 18
    • 79551543816 scopus 로고    scopus 로고
    • The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: A prospective single-center study
    • Sep 28. [Epub ahead of print]
    • Baldazzi V, Tassi R, Lapini A, Santomaggio C, Carini M, Mazzanti R. The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: A prospective single-center study. Urol Oncol. 2010. Sep 28. [Epub ahead of print].
    • (2010) Urol Oncol
    • Baldazzi, V.1    Tassi, R.2    Lapini, A.3    Santomaggio, C.4    Carini, M.5    Mazzanti, R.6
  • 19
    • 33846978108 scopus 로고    scopus 로고
    • Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib
    • Rini BI, Tamaskar I, Shaheen P, Salas R, Garcia J, Wood L, et al. Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst. 2007;99:81-3.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 81-83
    • Rini, B.I.1    Tamaskar, I.2    Shaheen, P.3    Salas, R.4    Garcia, J.5    Wood, L.6
  • 21
    • 78649360968 scopus 로고    scopus 로고
    • Clinical characteristics of thyroid abnormalities induced by sunitinib treatment in Japanese patients with renal cell carcinoma
    • Sato S, Muraishi K, Tani J, Sasaki Y, Tokubuchi I, Tajiri Y, et al. Clinical characteristics of thyroid abnormalities induced by sunitinib treatment in Japanese patients with renal cell carcinoma. Endocr J. 2010;57:873-80.
    • (2010) Endocr J , vol.57 , pp. 873-880
    • Sato, S.1    Muraishi, K.2    Tani, J.3    Sasaki, Y.4    Tokubuchi, I.5    Tajiri, Y.6
  • 22
    • 34248632840 scopus 로고    scopus 로고
    • Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity
    • Wong E, Rosen LS, Mulay M, Vanvugt A, Dinolfo M, Tomoda C, et al. Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity. Thyroid. 2007;17:351-5.
    • (2007) Thyroid , vol.17 , pp. 351-355
    • Wong, E.1    Rosen, L.S.2    Mulay, M.3    Vanvugt, A.4    Dinolfo, M.5    Tomoda, C.6
  • 25
    • 68949108390 scopus 로고    scopus 로고
    • Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer
    • Schlumberger MJ, Elisei R, Bastholt L, Wirth LJ, Martins RG, Locati LD, et al. Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer. J Clin Oncol. 2009;27:3794-801.
    • (2009) J Clin Oncol , vol.27 , pp. 3794-3801
    • Schlumberger, M.J.1    Elisei, R.2    Bastholt, L.3    Wirth, L.J.4    Martins, R.G.5    Locati, L.D.6
  • 26
    • 55549092771 scopus 로고    scopus 로고
    • Documentation of thyroid function in clinical studies with sunitinib: Why does it matter?
    • Garfield DH, Wolter P, Schoffski P, Hercbergs A, Davis P. Documentation of thyroid function in clinical studies with sunitinib: why does it matter? J Clin Oncol. 2008;26:5131-2.
    • (2008) J Clin Oncol , vol.26 , pp. 5131-5132
    • Garfield, D.H.1    Wolter, P.2    Schoffski, P.3    Hercbergs, A.4    Davis, P.5
  • 27
    • 78651361788 scopus 로고    scopus 로고
    • Hypothyroidism in patients with renal cell carcinoma: Blessing or curse?
    • Schmidinger M, Vogl UM, Bojic M, Lamm W, Heinzl H, Haitel A, et al. Hypothyroidism in patients with renal cell carcinoma: blessing or curse? Cancer. 2011;117:534-44.
    • (2011) Cancer , vol.117 , pp. 534-544
    • Schmidinger, M.1    Vogl, U.M.2    Bojic, M.3    Lamm, W.4    Heinzl, H.5    Haitel, A.6
  • 28
    • 81855163405 scopus 로고    scopus 로고
    • Hypothyroidism correlates with a better prognosis in metastatic renal cancer patients treated with sorafenib or sunitinib
    • Riesenbeck LM, Bierer S, Hoffmeister I, Kopke T, Papavassilis P, Hertle L, et al. Hypothyroidism correlates with a better prognosis in metastatic renal cancer patients treated with sorafenib or sunitinib. World J Urol. 2011;29(6):807-13.
    • (2011) World J Urol , vol.29 , Issue.6 , pp. 807-813
    • Riesenbeck, L.M.1    Bierer, S.2    Hoffmeister, I.3    Kopke, T.4    Papavassilis, P.5    Hertle, L.6
  • 29
    • 33750162642 scopus 로고    scopus 로고
    • Association between development of hypothyroidism and improved survival in patients with head and neck cancer
    • Nelson M, Hercbergs A, Rybicki L, Strome M. Association between development of hypothyroidism and improved survival in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg. 2006;132:1041-6.
    • (2006) Arch Otolaryngol Head Neck Surg , vol.132 , pp. 1041-1046
    • Nelson, M.1    Hercbergs, A.2    Rybicki, L.3    Strome, M.4
  • 30
    • 61649115441 scopus 로고    scopus 로고
    • The clinical implications of the genetics of renal cell carcinoma
    • Rosner I, Bratslavsky G, Pinto PA, Linehan WM. The clinical implications of the genetics of renal cell carcinoma. Urol Oncol. 2009;27:131-6.
    • (2009) Urol Oncol , vol.27 , pp. 131-136
    • Rosner, I.1    Bratslavsky, G.2    Pinto, P.A.3    Linehan, W.M.4
  • 31
    • 77955347059 scopus 로고    scopus 로고
    • AMG-386, a selective angiopoietin-1/-2-neutralizing peptibody for the potential treatment of cancer
    • Neal J, Wakelee H. AMG-386, a selective angiopoietin-1/-2-neutralizing peptibody for the potential treatment of cancer. Curr Opin Mol Ther. 2010;12:487-95.
    • (2010) Curr Opin Mol Ther , vol.12 , pp. 487-495
    • Neal, J.1    Wakelee, H.2
  • 32
    • 71949113638 scopus 로고    scopus 로고
    • Interim results from a phase 1b study of safety, pharmacokinetics (PK) and tumor response of the angiopoietin 1/2-neutralizing peptibody AMG 386 in combinations with AMG 706, bevacizumab (B) or sorafenib (S) in advanced solid tumors
    • Hong D, Gordon M, Appleman L, Kurzrock R, Sun Y, Rasmussen E, et al. Interim results from a phase 1b study of safety, pharmacokinetics (PK) and tumor response of the angiopoietin 1/2-neutralizing peptibody AMG 386 in combinations with AMG 706, bevacizumab (B) or sorafenib (S) in advanced solid tumors. Ann Oncol. 2008;19:154.
    • (2008) Ann Oncol , vol.19 , pp. 154
    • Hong, D.1    Gordon, M.2    Appleman, L.3    Kurzrock, R.4    Sun, Y.5    Rasmussen, E.6
  • 33
    • 33751565698 scopus 로고    scopus 로고
    • Treatment outcome for metastatic papillary renal cell carcinoma patients
    • Ronnen EA, Kondagunta GV, Ishill N, Spodek L, Russo P, Reuter V, et al. Treatment outcome for metastatic papillary renal cell carcinoma patients. Cancer. 2006;107(11):2617-21.
    • (2006) Cancer , vol.107 , Issue.11 , pp. 2617-2621
    • Ronnen, E.A.1    Kondagunta, G.V.2    Ishill, N.3    Spodek, L.4    Russo, P.5    Reuter, V.6
  • 34
    • 37849001813 scopus 로고    scopus 로고
    • Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma
    • Choueiri TK, Plantade A, Elson P, Negrier S, Ravaud A, Oudard S, et al. Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. J Clin Oncol. 2008;26(1):127-31.
    • (2008) J Clin Oncol , vol.26 , Issue.1 , pp. 127-131
    • Choueiri, T.K.1    Plantade, A.2    Elson, P.3    Negrier, S.4    Ravaud, A.5    Oudard, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.