Measles virus transmission from dendritic cells to T cells: Formation of synapse-like interfaces concentrating viral and cellular components

Journal of Virology

Volumn 86, Issue 18, 2012, Pages 9773-9781

  Koethe, Susanne ^a   Avota, Elita ^a   Schneider Schaulies, Sibylle ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CD209 ANTIGEN; CD81 ANTIGEN; EZRIN; GLYCOPROTEIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MOESIN; RADIXIN;

ARTICLE; BIOACCUMULATION; CELL SEPARATION; CONTROLLED STUDY; DENDRITIC CELL; FILOPODIUM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; MEASLES VIRUS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SYNAPSE; T LYMPHOCYTE ACTIVATION; VIRUS CELL INTERACTION; VIRUS ENTRY; VIRUS TRANSMISSION;

ANTIGENS, CD; CELL ADHESION MOLECULES; DENDRITIC CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOLOGICAL SYNAPSES; LECTINS, C-TYPE; MEASLES; MEASLES VIRUS; RECEPTORS, CELL SURFACE; RECEPTORS, VIRUS; T-LYMPHOCYTES; VIRAL PROTEINS;

MEASLES VIRUS;

EID: 84866179283     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00458-12     Document Type: Article

References (50)

1. Albrecht P, Shabo AL, Burns GR, Tauraso NM. 1972. Experimental measles encephalitis in normal and cyclophosphamide-treated rhesus monkeys. J. Infect. Dis. 126: 154-161.
2. Avota E, Gulbins E, Schneider-Schaulies S. 2011. DC-SIGN-mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells. PLoS Pathog. 7: e1001290. doi:10.1371/journal.ppat.1001290.
3. Barrero-Villar M, et al. 2009. Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion, and viral infection in lymphocytes. J. Cell Sci. 122: 103-113.
4. Condack C, Grivel JC, Devaux P, Margolis L, Cattaneo R. 2007. Measles virus vaccine attenuation: suboptimal infection of lymphatic tissue and tropism alteration. J. Infect. Dis. 196: 541-549.
5. + lymphocytes and dendritic cells during measles virus infection of macaques. PLoS Pathog. 3: e178. doi:10.1371/journal.ppat.0030178.
6. de Vries RD, et al. 2010. In vivo tropism of attenuated and pathogenic measles virus expressing green fluorescent protein in macaques. J. Virol. 84: 4714-4724.
7. de Witte L, Abt M, Schneider-Schaulies S, van Kooyk Y, Geijtenbeek TB. 2006. Measles virus targets DC-SIGN to enhance dendritic cell infection. J. Virol. 80: 3477-3486.
8. de Witte L, et al. 2008. DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes. PLoS Pathog. 4: e1000049. doi:10.1371/journal.ppat.1000049.
9. Dunster LM, et al. 1995. Moesin, and not the murine functional homologue (Crry/p65) of human membrane cofactor protein (CD46), is involved in the entry of measles virus (strain Edmonston) into susceptible murine cell lines. J. Gen. Virol. 76(Pt 8): 2085-2089.
10. Dunster LM, et al. 1994. Moesin: a cell membrane protein linked with susceptibility to measles virus infection. Virology 198: 265-274.
11. Eugenin EA, Gaskill PJ, Berman JW. 2009. Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: a potential mechanism for intercellular HIV trafficking. Cell. Immunol. 254: 142-148.
12. Felts RL, et al. 2010. 3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proc. Natl. Acad. Sci. U. S. A. 107: 13336-13341.
13. Ferreira CS, et al. 2010. Measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (SLAM, CD150). J. Virol. 84: 3033-3042.
14. Gassert E, et al. 2009. Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression. PLoS Pathog. 5: e1000623. doi:10.1371/journal.ppat.1000623.
15. Griffin DE. 2010. Measles virus-induced suppression of immune responses. Immunol. Rev. 236: 176-189.
16. + T cells. J. Exp. Med. 186: 801-812.
17. Hahm B, Arbour N, Oldstone MB. 2004. Measles virus interacts with human SLAM receptor on dendritic cells to cause immunosuppression. Virology 323: 292-302.
18. Haller C, Fackler OT. 2008. HIV-1 at the immunological and T-lymphocytic virological synapse. Biol. Chem. 389: 1253-1260.
19. Harrowe G, Mitsuhashi M, Payan DG. 1990. Measles virus-substance P receptor interactions: possible novel mechanism of viral fusion. J. Clin. Invest. 85: 1324-1327.
20. Harrowe G, Sudduth-Klinger J, Payan DG. 1992. Measles virussubstance P receptor interaction: Jurkat lymphocytes transfected with substance P receptor cDNA enhance measles virus fusion and replication. Cell. Mol. Neurobiol. 12: 397-409.
21. Hashiguchi T, et al. 2011. Structure of the measles virus hemagglutinin bound to its cellular receptor SLAM. Nat. Struct. Mol. Biol. 18: 135-141.
22. Iyengar S, Hildreth JE, Schwartz DH. 1998. Actin-dependent receptor colocalization required for human immunodeficiency virus entry into host cells. J. Virol. 72: 5251-5255.
23. Jimenez-Baranda S, et al. 2007. Filamin-A regulates actin-dependent clustering of HIV receptors. Nat. Cell Biol. 9: 838-846.
24. Jolly C, Mitar I, Sattentau QJ. 2007. Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells. J. Virol. 81: 13916-13921.
25. Jolly C, Sattentau QJ. 2004. Retroviral spread by induction of virological synapses. Traffic 5: 643-650.
26. Kerdiles YM, Sellin CI, Druelle J, Horvat B. 2006. Immunosuppression caused by measles virus: role of viral proteins. Rev. Med. Virol. 16: 49-63.
27. Kobune F, et al. 1996. Nonhuman primate models of measles. Lab. Anim. Sci. 46: 315-320.
28. Lehmann M, Nikolic DS, Piguet V. 2011. How HIV-1 takes advantage of the cytoskeleton during replication and cell-to-cell transmission. Viruses 3: 1757-1776.
29. Lemon K, et al. 2011. Early target cells of measles virus after aerosol infection of non-human primates. PLoS Pathog. 7: e1001263. doi:10.1371/journal.ppat.1001263.
30. Makhortova NR, et al. 2007. Neurokinin-1 enables measles virus transsynaptic spread in neurons. Virology 362: 235-244.
31. McChesney MB, Fujinami RS, Lerche NW, Marx PA, Oldstone MB. 1989. Virus-induced immunosuppression: infection of peripheral blood mononuclear cells and suppression of immunoglobulin synthesis during natural measles virus infection of rhesus monkeys. J. Infect. Dis. 159: 757-760.
32. McDonald D, et al. 2003. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science 300: 1295-1297.
33. Muller N, et al. 2006. Measles virus contact with T cells impedes cytoskeletal remodeling associated with spreading, polarization, and CD3 clustering. Traffic 7: 849-858.
34. Nikolic DS, et al. 2011. HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation. Blood 118: 4841-4852.
35. Ohno S, et al. 2007. Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection. J. Virol. 81: 1650-1659.
36. Okada H, et al. 2000. Extensive lymphopenia due to apoptosis of uninfected lymphocytes in acute measles patients. Arch. Virol. 145: 905-920.
37. Pohl C, Shishkova J, Schneider-Schaulies S. 2007. Viruses and dendritic cells: enemy mine. Cell Microbiol. 9: 279-289.
38. Schneider-Schaulies J, Dunster LM, Schwartz-Albiez R, Krohne G, ter Meulen V. 1995. Physical association of moesin and CD46 as a receptor complex for measles virus. J. Virol. 69: 2248-2256.
39. Schneider-Schaulies S, Schneider-Schaulies J. 2009. Measles virusinduced immunosuppression. Curr. Top. Microbiol. Immunol. 330: 243-269.
40. Servet-Delprat C, et al. 2000. Measles virus induces abnormal differentiation of CD40 ligand-activated human dendritic cells. J. Immunol. 164: 1753-1760.
41. Servet-Delprat C, Vidalain PO, Valentin H, Rabourdin-Combe C. 2003. Measles virus and dendritic cell functions: how specific response cohabits with immunosuppression. Curr. Top. Microbiol. Immunol. 276: 103-123.
42. Shishkova Y, Harms H, Krohne G, Avota E, Schneider-Schaulies S. 2007. Immune synapses formed with measles virus-infected dendritic cells are unstable and fail to sustain T cell activation. Cell Microbiol. 9: 1974-1986.
43. Sowinski S, Alakoskela JM, Jolly C, Davis DM. 2011. Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1. Methods 53: 27-33.
44. Steffens CM, Hope TJ. 2003. Localization of CD4 and CCR5 in living cells. J. Virol. 77: 4985-4991.
45. Stolp B, Fackler OT. 2011. How HIV takes advantage of the cytoskeleton in entry and replication. Viruses 3: 293-311.
46. Tran-Van H, Avota E, Bortlein C, Mueller N, Schneider-Schaulies S. 2011. Measles virus modulates dendritic cell/T-cell communication at the level of plexinA1/neuropilin-1 recruitment and activity. Eur. J. Immunol. 41: 151-163.
47. van Binnendijk RS, Poelen MC, van Amerongen G, de Vries P, Osterhaus AD. 1997. Protective immunity in macaques vaccinated with live attenuated, recombinant, and subunit measles vaccines in the presence of passively acquired antibodies. J. Infect. Dis. 175: 524-532.
48. van der Vlist M, et al. 2011. Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4 T cells but are incapable of cross-presentation. Eur. J. Immunol. 41: 2619-2631.
49. + T cells. Virology 381: 143-154.
50. Yanagi Y, Takeda M, Ohno S. 2006. Measles virus: cellular receptors, tropism and pathogenesis. J. Gen. Virol. 87: 2767-2779.