Competitive incorporation of homologous gene segments of influenza A virus into virions

Journal of Virology

Volumn 86, Issue 18, 2012, Pages 10200-10202

  Inagaki, Arisa ^a   Goto, Hideo ^a   Kakugawa, Satoshi ^a   Ozawa, Makoto ^b   Kawaoka, Yoshihiro ^a,c,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN; VIRUS RNA;

5' UNTRANSLATED REGION; ARTICLE; BINDING COMPETITION; GENE CASSETTE; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; INFLUENZA VIRUS A; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; REPORTER GENE; RNA REPLICATION; RNA SEQUENCE; RNA TRANSCRIPTION; VIRION; VIRUS GENE; VIRUS PLAQUE; VIRUS RECOMBINANT; VIRUS REPLICATION;

ANIMALS; CELL LINE; DOGS; GENES, REPORTER; GENES, VIRAL; HUMANS; INFLUENZA A VIRUS; NEURAMINIDASE; PLASMIDS; RECOMBINANT PROTEINS; RNA REPLICASE; RNA, VIRAL; TRANSFECTION; VIRAL PROTEINS; VIRION; VIRUS ASSEMBLY;

INFLUENZA A VIRUS;

EID: 84866161296     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01204-12     Document Type: Article

References (18)

1. Dos Santos Afonso E, Escriou N, Leclercq I, van der Werf S, Naffakh N. 2005. The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5' end of the PB2 segment. Virology 341:34-46.
2. Fournier E, et al. 2012. A supramolecular assembly formed by influenza A virus genomic RNA segments. Nucleic Acids Res. 40:2197-2209.
3. Fujii K, et al. 2005. Importance of both the coding and the segment-specific noncoding regions of the influenza A virus NS segment for its efficient incorporation into virions. J. Virol. 79:3766-3774.
4. Fujii Y, Goto H, Watanabe T, Yoshida T, Kawaoka Y. 2003. Selective incorporation of influenza virus RNA segments into virions. Proc. Natl. Acad. Sci. U. S. A. 100:2002-2007.
5. Gog JR, et al. 2007. Codon conservation in the influenza A virus genome defines RNA packaging signals. Nucleic Acids Res. 35:1897-1907.
6. Liang Y, Hong Y, Parslow TG. 2005. cis-Acting packaging signals in the influenza virus PB1, PB2, and PA genomic RNA segments. J. Virol. 79: 10348-10355.
7. Liang Y, Huang T, Ly H, Parslow TG, Liang Y. 2008. Mutational analyses of packaging signals in influenza virus PA, PB1, and PB2 genomic RNA segments. J. Virol. 82:229-236.
8. Marsh GA, Hatami R, Palese P. 2007. Specific residues of the influenza A virus hemagglutinin viral RNA are important for efficient packaging into budding virions. J. Virol. 81:9727-9736.
9. Marsh GA, Rabadan R, Levine AJ, Palese P. 2008. Highly conserved regions of influenza a virus polymerase gene segments are critical for efficient viral RNA packaging. J. Virol. 82:2295-2304.
10. Muramoto Y, et al. 2006. Hierarchy among viral RNA (vRNA) segments in their role in vRNA incorporation into influenza A virions. J. Virol. 80:2318-2325.
11. Neumann G, et al. 1999. Generation of influenza A viruses entirely from cloned cDNAs. Proc. Natl. Acad. Sci. U. S. A. 96:9345-9350.
12. Noda T, et al. 2006. Architecture of ribonucleoprotein complexes in influenza A virus particles. Nature 439:490-492.
13. Noda T, et al. 2012. Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus. Nat. Commun. 3:639.
14. Ozawa M, et al. 2007. Contributions of two nuclear localization signals of influenza A virus nucleoprotein to viral replication. J. Virol. 81:30-41.
15. Ozawa M, et al. 2009. Nucleotide sequence requirements at the 5' end of the influenza A virus M RNA segment for efficient virus replication. J. Virol. 83:3384-3388.
16. Ozawa M, et al. 2011. Replication-incompetent influenza A viruses that stably express a foreign gene. J. Gen. Virol. 92:2879-2888.
17. Palese P, Schulman JL. 1976. Differences in RNA patterns of influenza A viruses. J. Virol. 17:876-884.
18. Palese P, Shaw ML. 2007. Orthomyxoviridae: the viruses and their replication, p 1647-1689. In Knipe DM, HowleyPM(ed), Fields virology, 5th ed. Lippincott-Raven Publishers, Philadelphia, PA.